Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ngin Cin Khai"'
Autor:
Hisayoshi Fujiwara, Ken-ichiro Kosai, Kazuko Goto, Takako Fujiwara, Kentaro Yuge, Ngin Cin Khai, Tomoyuki Takahashi
Publikováno v:
International Journal of Molecular Medicine
Inflammatory bowel disease (IBD) severely affects the quality of life of patients. At present, there is no clinical solution for this condition; therefore, there is a need for innovative therapies for IBD. Hepatocyte growth factor (HGF) exerts variou
Autor:
Hiroto Terasaki, Ngin Cin Khai, Taiji Sakamoto, Ken-ichiro Kosai, Saori Tokushige, Y. J. Wang, Taro Kamisasanuki
Publikováno v:
Biochemical and Biophysical Research Communications. 413:128-135
The precise roles of tetraspanin CD9 are unclear. Here we show that CD9 plays a stimulus-independent role in angiogenesis and that inhibiting CD9 expression or function is a potential antiangiogenic therapy. Knocking down CD9 expression significantly
Autor:
Xue-Hai Chen, Kentaro Yuge, Tomoyuki Takahashi, Rumi Maruyama, Hiroaki Ushikoshi, Ngin Cin Khai, Shinya Minatoguchi, Kazuko Goto, Takao Kawai, Takako Fujiwara, Satoshi Nagano, Masayasu Esaki, Genzou Takemura, Ken-ichiro Kosai, Hisayoshi Fujiwara, Yoshiteru Murofushi
Publikováno v:
Laboratory Investigation. 85:862-873
Insulin-like growth factor (IGF), hepatocyte growth factor (HGF), and heparin-binding epidermal growth factor-like growth factor (HB-EGF) are cardiogenic and cardiohypertrophic growth factors. Although the therapeutic effects of IGF and HGF have been
Publikováno v:
Hepatology Research. 41:594-596
Autor:
Hisayoshi Fujiwara, Atsushi Ogino, Hiromitsu Kanamori, Rumi Maruyama, Shinya Minatoguchi, Shusaku Miyata, Longhu Li, Genzou Takemura, Yiwen Li, Ngin Cin Khai, Masayasu Esaki, Hideshi Okada, Takako Fujiwara
Publikováno v:
Circulation. 113(4)
Background— Doxorubicin is a highly effective antineoplastic drug, but its clinical use is limited by its adverse side effects on the heart. We investigated possible protective effects of erythropoietin against doxorubicin-induced cardiomyopathy. M
Autor:
Satoshi Nagano, Yasuhiro Terazaki, Ngin Cin Khai, Hisayoshi Fujiwara, Takao Kawai, Ken-ichiro Kosai, Kentaro Yuge, Hiroaki Ushikoshi, Tomoyuki Takahashi, Toshikazu Nakamura, Yoshiteru Murofushi
Publikováno v:
International journal of oncology. 27(1)
Hepatocyte growth factor (HGF) gene therapy may have potential for treating chronic hepatitis (CH) and liver cirrhosis (LC). However, the lack of an HGF gene therapy study on hepatomas that are often associated with CH or LC, together with the stimul
Autor:
Takao Kawai, Takako Fujiwara, Kazuko Goto, Ngin Cin Khai, Ken-ichiro Kosai, Satoshi Nagano, Hisayoshi Fujiwara, Kentaro Yuge, Masayasu Esaki, Tomoyuki Takahashi, Hiroaki Ushikoshi, Yoshiteru Murofushi
Publikováno v:
Journal of hepatology. 44(6)
Background/Aims It is unknown whether heparin-binding EGF-like growth factor (HB-EGF) can be a therapeutic agent, although previous studies suggested that HB-EGF might be a hepatotrophic factor. This study explores the potential of hepatic HB-EGF gen
Autor:
Ken-ichiro Kosai, Tomoyuki Takahashi, Yiwen Li, Kentaro Yuge, Ngin Cin Khai, Shusaku Miyata, Rumi Maruyama, Satoshi Nagano, Takako Fujiwara, Atsushi Mikami, Hisayoshi Fujiwara, Masayasu Esaki, Shinya Minatoguchi, Kazuko Goto, Hideshi Okada, Genzou Takemura
Publikováno v:
Circulation research. 95(6)
In myocardial infarction (MI), granulation tissue cells disappear via apoptosis to complete a final scarring with scanty cells. Blockade of this apoptosis was reported to improve post-MI ventricular remodeling and heart failure. However, the molecula
Autor:
KOUICHI SAKAMOTO, NGIN CIN KHAI, YUQING WANG, RIE IRIE, HIDEO TAKAMATSU, HIROSHI MATSUFUJI, KEN-ICHIRO KOSAI
Publikováno v:
International Journal of Molecular Medicine; 2016, Vol. 38 Issue 6, p1673-1682, 10p