Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Nghiemphu PL"'
Autor:
Harris, RJ, Yao, J, Chakhoyan, A, Raymond, C, Leu, K, Liau, LM, Nghiemphu, PL, Lai, A, Salamon, N, Pope, WB, Cloughesy, TF, Ellingson, BM
Publikováno v:
Magnetic resonance in medicine, vol 80, iss 5
Harris, RJ; Yao, J; Chakhoyan, A; Raymond, C; Leu, K; Liau, LM; et al.(2018). Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI). MAGNETIC RESONANCE IN MEDICINE, 80(5), 1962-1978. doi: 10.1002/mrm.27204. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5wn372jw
Harris, RJ; Yao, J; Chakhoyan, A; Raymond, C; Leu, K; Liau, LM; et al.(2018). Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI). MAGNETIC RESONANCE IN MEDICINE, 80(5), 1962-1978. doi: 10.1002/mrm.27204. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5wn372jw
PURPOSE:To introduce a new pH-sensitive and oxygen-sensitive MRI technique using amine proton CEST echo spin-and-gradient echo (SAGE) EPI (CEST-SAGE-EPI). METHODS:pH-weighting was obtained using CEST estimations of magnetization transfer ratio asymme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::36b86b28e5f1fa64164c3ccd92018148
https://escholarship.org/uc/item/5wn372jw
https://escholarship.org/uc/item/5wn372jw
Publikováno v:
NMR in biomedicine, vol 29, iss 11
Harris, RJ; Cloughesy, TF; Liau, LM; Nghiemphu, PL; Lai, A; Pope, WB; et al.(2016). Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3T. NMR IN BIOMEDICINE, 29(11), 1563-1576. doi: 10.1002/nbm.3611. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4rx0p2g9
Harris, RJ; Cloughesy, TF; Liau, LM; Nghiemphu, PL; Lai, A; Pope, WB; et al.(2016). Simulation, phantom validation, and clinical evaluation of fast pH-weighted molecular imaging using amine chemical exchange saturation transfer echo planar imaging (CEST-EPI) in glioma at 3T. NMR IN BIOMEDICINE, 29(11), 1563-1576. doi: 10.1002/nbm.3611. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4rx0p2g9
Acidity within the extracellular milieu is a hallmark of cancer. There is a current need for fast, high spatial resolution pH imaging techniques for clinical evaluation of cancers, including gliomas. Chemical exchange saturation transfer (CEST) MRI t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::393ae921762109689b30367b01bfd3f7
https://escholarship.org/uc/item/4rx0p2g9
https://escholarship.org/uc/item/4rx0p2g9
Publikováno v:
Journal of magnetic resonance imaging : JMRI, vol 44, iss 5
Leu, K; Boxerman, JL; Lai, A; Nghiemphu, PL; Pope, WB; Cloughesy, TF; et al.(2016). Bidirectional Contrast agent leakage correction of dynamic susceptibility contrast (DSC)-MRI improves cerebral blood volume estimation and survival prediction in recurrent glioblastoma treated with bevacizumab. JOURNAL OF MAGNETIC RESONANCE IMAGING, 44(5), 1229-1237. doi: 10.1002/jmri.25227. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4c23w0fb
Leu, K; Boxerman, JL; Lai, A; Nghiemphu, PL; Pope, WB; Cloughesy, TF; et al.(2016). Bidirectional Contrast agent leakage correction of dynamic susceptibility contrast (DSC)-MRI improves cerebral blood volume estimation and survival prediction in recurrent glioblastoma treated with bevacizumab. JOURNAL OF MAGNETIC RESONANCE IMAGING, 44(5), 1229-1237. doi: 10.1002/jmri.25227. UCLA: Retrieved from: http://www.escholarship.org/uc/item/4c23w0fb
PurposeTo evaluate a leakage correction algorithm for T1 and T2* artifacts arising from contrast agent extravasation in dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) that accounts for bidirectional contrast agent flux and compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4602775386f54e83ba7328218a7e6003
https://escholarship.org/uc/item/4c23w0fb
https://escholarship.org/uc/item/4c23w0fb
Autor:
Ellingson, BM, Nguyen, HN, Lai, A, Nechifor, RE, Zaw, O, Pope, WB, Yong, WH, Nghiemphu, PL, Liau, LM, Cloughesy, TF
Publikováno v:
Cancer, vol 122, iss 11
Ellingson, BM; Nguyen, HN; Lai, A; Nechifor, RE; Zaw, O; Pope, WB; et al.(2016). Contrast-Enhancing Tumor Growth Dynamics of Preoperative, Treatment-Naive Human Glioblastoma. CANCER, 122(11), 1718-1727. doi: 10.1002/cncr.29957. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1bt317dx
Ellingson, BM; Nguyen, HN; Lai, A; Nechifor, RE; Zaw, O; Pope, WB; et al.(2016). Contrast-Enhancing Tumor Growth Dynamics of Preoperative, Treatment-Naive Human Glioblastoma. CANCER, 122(11), 1718-1727. doi: 10.1002/cncr.29957. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1bt317dx
BackgroundLittle is known about the natural growth characteristics of untreated glioblastoma before surgical or therapeutic intervention, because patients are rapidly treated after preliminary radiographic diagnosis. Understanding the growth characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::193b2899bbe1b10937c7f5518143028c
https://escholarship.org/uc/item/1bt317dx
https://escholarship.org/uc/item/1bt317dx
Publikováno v:
Ellingson, BM; Lai, A; Nguyen, HN; Nghiemphu, PL; Pope, WB; & Cloughesy, TF. (2015). Quantification of Nonenhancing tumor burden in Gliomas using effective T2maps derived from dual-echo turbo spin-echo MRI. Clinical Cancer Research, 21(19), 4373-4383. doi: 10.1158/1078-0432.CCR-14-2862. UCLA: Retrieved from: http://www.escholarship.org/uc/item/8bd4f17f
Purpose: Evaluation of nonenhancing tumor (NET) burden is an important yet challenging part of brain tumor response assessment. This study focuses on using dual-echo turbo spin-echo MRI as a means of quickly estimating tissue T2, which can be used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::6581cf466f88a9c37ad0955b812e6d02
http://www.escholarship.org/uc/item/8bd4f17f
http://www.escholarship.org/uc/item/8bd4f17f
Autor:
Harris, RJ, Cloughesy, TF, Hardy, AJ, Liau, LM, Pope, WB, Nghiemphu, PL, Lai, A, Ellingson, BM
Publikováno v:
Harris, RJ; Harris, RJ; Cloughesy, TF; Hardy, AJ; Hardy, AJ; Liau, LM; et al.(2015). MRI perfusion measurements calculated using advanced deconvolution techniques predict survival in recurrent glioblastoma treated with bevacizumab. Journal of Neuro-Oncology. doi: 10.1007/s11060-015-1755-8. UCLA: Retrieved from: http://www.escholarship.org/uc/item/2d81809r
© 2015 Springer Science+Business Media New York Bevacizumab is a therapeutic drug used in treatment of recurrent glioblastoma to inhibit angiogenesis. Treatment response is often monitored through the use of perfusion MRI measures of cerebral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::914826628dccf2f5347f4a3771d13144
http://www.escholarship.org/uc/item/2d81809r
http://www.escholarship.org/uc/item/2d81809r
Autor:
Karavaeva, E, Harris, RJ, Leu, K, Shabihkhani, M, Yong, WH, Pope, WB, Lai, A, Nghiemphu, PL, Liau, LM, Chen, W, Czernin, J, Cloughesy, TF, Ellingson, BM
Publikováno v:
Karavaeva, E; Harris, RJ; Harris, RJ; Leu, K; Leu, K; Shabihkhani, M; et al.(2014). Relationship Between [18F]FDOPA PET Uptake, Apparent Diffusion Coefficient (ADC), and Proliferation Rate in Recurrent Malignant Gliomas. Molecular Imaging and Biology. doi: 10.1007/s11307-014-0807-3. UCLA: Retrieved from: http://www.escholarship.org/uc/item/6j6650t8
© 2014 World Molecular Imaging Society Purpose: Diffusion magnetic resonance imaging (MRI) and 6-[18F]fluoro-l-dopa ([18F]FDOPA) positron emission tomography (PET) are used to interrogate malignant tumor microenvironment. It remains unclear whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::3fc7a6e1371201837041a728a5f4e89f
http://www.escholarship.org/uc/item/6j6650t8
http://www.escholarship.org/uc/item/6j6650t8
Autor:
White, CM, Pope, WB, Zaw, T, Qiao, J, Naeini, KM, Lai, A, Nghiemphu, PL, Wang, JJ, Cloughesy, TF, Ellingson, BM
Publikováno v:
Journal of neuroimaging : official journal of the American Society of Neuroimaging, vol 24, iss 1
White, CM; Pope, WB; Zaw, T; Qiao, J; Naeini, KM; Lai, A; et al.(2014). Regional and Voxel-Wise Comparisons of Blood Flow Measurements Between Dynamic Susceptibility Contrast Magnetic Resonance Imaging (DSC-MRI) and Arterial Spin Labeling (ASL) in Brain Tumors. Journal of Neuroimaging, 24(1), 23-30. doi: 10.1111/j.1552-6569.2012.00703.x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7w0448s2
White, CM; Pope, WB; Zaw, T; Qiao, J; Naeini, KM; Lai, A; et al.(2014). Regional and Voxel-Wise Comparisons of Blood Flow Measurements Between Dynamic Susceptibility Contrast Magnetic Resonance Imaging (DSC-MRI) and Arterial Spin Labeling (ASL) in Brain Tumors. Journal of Neuroimaging, 24(1), 23-30. doi: 10.1111/j.1552-6569.2012.00703.x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7w0448s2
The objective of the current study was to evaluate the regional and voxel-wise correlation between dynamic susceptibility contrast (DSC) and arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI) measurement of cerebral blood flow (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::038621c1d7c8d07f5649054626057e2e
https://escholarship.org/uc/item/7w0448s2
https://escholarship.org/uc/item/7w0448s2
Autor:
Lalezari, S, Chou, AP, Tran, A, Solis, OE, Khanlou, N, Chen, W, Li, S, Carrillo, JA, Chowdhury, R, Selfridge, J, Sanchez, DE, Wilson, RW, Zurayk, M, Lalezari, J, Lou, JJ, Ormiston, L, Ancheta, K, Hanna, R, Miller, P, Piccioni, D, Ellingson, BM, Buchanan, C, Mischel, PS, Nghiemphu, PL, Green, R, Wang, HJ, Pope, WB, Liau, LM, Elashoff, RM, Cloughesy, TF, Yong, WH, Lai, A
Publikováno v:
Lalezari, S; Chou, AP; Tran, A; Solis, OE; Khanlou, N; Chen, W; et al.(2013). Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome. Neuro-Oncology, 15(3), 370-381. doi: 10.1093/neuonc/nos308. UCLA: Retrieved from: http://www.escholarship.org/uc/item/5fc2v4np
BackgroundPromoter methylation of the DNA repair gene, O-6-methylguanine- DNA methyltransferase (MGMT), is associated with improved treatment outcome for newly diagnosed glioblastoma (GBM) treated with standard chemoradiation. To determine the progno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::de013e6497d0abc7e6feddeae9da6761
http://www.escholarship.org/uc/item/5fc2v4np
http://www.escholarship.org/uc/item/5fc2v4np
Autor:
Carrillo, JA, Lai, A, Nghiemphu, PL, Kim, HJ, Phillips, HS, Kharbanda, S, Moftakhar, P, Lalaezari, S, Yong, W, Ellingson, BM, Cloughesy, TF, Pope, WB
Publikováno v:
Carrillo, JA; Lai, A; Nghiemphu, PL; Kim, HJ; Phillips, HS; Kharbanda, S; et al.(2012). Relationship between tumor enhancement, edema, IDH1 mutational status, MGMT promoter methylation, and survival in glioblastoma. American Journal of Neuroradiology, 33(7), 1349-1355. doi: 10.3174/ajnr.A2950. UCLA: Retrieved from: http://www.escholarship.org/uc/item/263873gp
AJNR. American journal of neuroradiology, vol 33, iss 7
AJNR. American journal of neuroradiology, vol 33, iss 7
BACKGROUND AND PURPOSE: Both IDH1 mutation and MGMT promoter methylation are associated with longer survival. We investigated the ability of imaging correlates to serve as noninvasive biomarkers for these molecularly defined GBM subtypes. MATERIALS A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d8ba84a3fe358738d5cb9aa7ac213ca
http://www.escholarship.org/uc/item/263873gp
http://www.escholarship.org/uc/item/263873gp