Zobrazeno 1 - 10 of 34 pro vyhledávání: '"Nghia H. Pham"'
3
β-Lactam Antibiotics
Autor: Brian A. Baldo, Nghia H. Pham
Publikováno v: Drug Allergy ISBN: 9783030517397
Drug Allergy ISBN: 9781461472605
The β-lactam antibiotics comprise four main classes of drugs; penams (penicillins), cephems (cephalosporins), monobactams, and carbapenems. Penicillins can cause all four types of hypersensitivity responses. IgE antibodies in patients’ sera detect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c99fc7f95099b9c48e71b8e0596cdf
https://doi.org/10.1007/978-3-030-51740-3_5
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4
Proton Pump Inhibitors
Autor: Brian A. Baldo, Nghia H. Pham
Publikováno v: Drug Allergy ISBN: 9783030517397
Drug Allergy ISBN: 9781461472605
Proton pump inhibitors (PPIs), omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole, and dexlansoprazole bind irreversibly to the H+, K+- ATPase (the “proton pump”) inhibiting its activity and decreasing gastric acid production. Syst
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05cd0b6c5c172b8bac4da2dbc53fcb2c
https://doi.org/10.1007/978-3-030-51740-3_12
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5
Scope of this Book: Adverse Reactions to Drugs and Drug Allergy
Autor: Nghia H. Pham, Brian A. Baldo
Publikováno v: Drug Allergy ISBN: 9783030517397
In what is essentially a pharmacologically based classification of adverse drug reactions (ADRs), unpredictable and dose-independent drug reactions, designated type B reactions, are made up of immune-mediated and non-immune sensitivities. The former
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd3f523e6026adf11a1d6804e4722941
https://doi.org/10.1007/978-3-030-51740-3_1
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6
Non-targeted Drugs for Cancer Therapy
Autor: Brian A. Baldo, Nghia H. Pham
Publikováno v: Drug Allergy ISBN: 9783030517397
In a 2017 analysis, 61 of 150 anticancer drugs approved by the FDA were classified as cytotoxic and 89 as targeted drugs. For many years, cytotoxic compounds have been the front line of cancer chemotherapy, but their action of destroying rapidly divi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3dbb85c4f8cbe7b30ba38ac365d51bb7
https://doi.org/10.1007/978-3-030-51740-3_15
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7
Targeted Drugs for Cancer Therapy: Small Molecules and Monoclonal Antibodies
Autor: Brian A. Baldo, Nghia H. Pham
Publikováno v: Drug Allergy ISBN: 9783030517397
Specific targeting of tumor cells without inflicting collateral damage on normal healthy cells has been, and remains, a long-standing aim in cancer therapy. Effective targeting of tumor cells without accompanying toxicity has started to be realized w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::113ef3f2e609911e8cc2cdfe4d563e93
https://doi.org/10.1007/978-3-030-51740-3_14
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8
Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones
Autor: Nghia H. Pham, Brian A. Baldo
Publikováno v: Drug Allergy ISBN: 9783030517397
Proteins dominate the extensive and growing list of approved biotherapeutic agents used in medicine today. Proteins, as targeted antibodies, tiny concentrations of hormones and cytokines; many enzymes; fusion proteins and receptors; “factors” inv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04b86c065ebf3e59ec582aa100e27972
https://doi.org/10.1007/978-3-030-51740-3_13
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10
Non-steroidal Anti-inflammatory Drugs
Autor: Brian A. Baldo, Nghia H. Pham
Publikováno v: Drug Allergy ISBN: 9783030517397
Non-steroidal anti-inflammatory drugs (NSAIDs) are responsible for 20–25% of ADRs. Cyclooxygenase isoenzymes COX-1 and COX-2 catalyze the formation of PGG2 from arachidonic acid. Ultimate products of the metabolic pathway are PGD2, PGE2, PGF2α, PG
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bf6dbe0842f88a0ee7ebf2eb6472823
https://doi.org/10.1007/978-3-030-51740-3_9
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