CRISPR Cas9-mediated ablation of pyruvate carboxylase gene in colon cancer cell line HT-29 inhibits growth and migration, induces apoptosis and increases sensitivity to 5-fluorouracil and glutaminase inhibitor

Autor: Ngamkham, Jarunya, Siritutsoontorn, Siraprapa, Saisomboon, Saowaluk, Vaeteewoottacharn, Kulthida, Jitrapakdee, Sarawut

Publikováno v: Frontiers in Oncology. 12

Pyruvate carboxylase (PC) is an important anaplerotic enzyme that replenishes the tricarboxylic acid cycle (TCA) intermediates. It prevents the collapse of the TCA cycle upon its intermediates are removed during high anabolic demand. We have recently

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https://doi.org/10.3389/fonc.2022.966089

Sourcing of the WHO human papillomavirus type 18 international standards for HPV antibody levels

Autor: Faust, Helena, Eklund, Carina, Sukvirach, Sukhon, Ngamkham, Jarunya, Dillner, Joakim

Publikováno v: In Journal of Clinical Virology May 2016 78:89-92

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The components and anticancer activity of the volatile oil from Streblus asper.

Autor: Phutdhawong, Weerachai, Donchai, Arworn, Korth, John, Pyne, Stephen G., Picha, Porntipa, Ngamkham, Jarunya, Buddhasukh, Duang

Publikováno v: Flavour & Fragrance Journal; Sep2004, Vol. 19 Issue 5, p445-447, 3p

Targeting Cancer Metabolism and Current Anti-Cancer Drugs.

Autor: Sukjoi W; Faculty of Science, Department of Biochemistry, Mahidol University, Bangkok, Thailand., Ngamkham J; Graduate Program in Molecular Medicine, Multidisciplinary Unit, Faculty of Science, Mahidol University, Bangkok, Thailand., Attwood PV; School of Molecular Sciences, The University of Western Australia, Perth, WA, USA., Jitrapakdee S; Faculty of Science, Department of Biochemistry, Mahidol University, Bangkok, Thailand. sarawut.jit@mahidol.ac.th.

Publikováno v: Advances in experimental medicine and biology [Adv Exp Med Biol] 2021; Vol. 1286, pp. 15-48.