Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ngalle Eric Mbua"'
Autor:
Emmanuel E Nekongo, Ngalle Eric Mbua, Jun Guo, Selvanathan Arumugam, Vladimir V. Popik, Nannan Lin, Frédéric Friscourt, Geert-Jan Boons
Publikováno v:
Chem. Sci.. 5:1591-1598
The selective derivatization of solvent-exposed cysteine residues in peptides and proteins is achieved by brief irradiation of an aqueous solution containing 3-(hydroxymethyl)-2-naphthol derivatives (NQMPs) with a 350 nm fluorescent lamp. NQMP can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2b189704a10b933d984fa838a4b4bd
https://doi.org/10.1039/c3sc51691a
https://doi.org/10.1039/c3sc51691a
Autor:
Sara V. Orski, Geert-Jan Boons, Ngalle Eric Mbua, Selvanathan Arumugam, Christopher D. McNitt, Jason Locklin, Vladimir V. Popik
Publikováno v:
Pure and Applied Chemistry. 85:1499-1513
Three photo-click ligation strategies described in this account provide scientists with efficient and selective tools for derivatization of various molecules, polymers, and surfaces. Fast photochemical reactions that are utilized in these techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d28efb511dac7d38ce1fe52d15b8c582
https://doi.org/10.1351/pac-con-13-01-08
https://doi.org/10.1351/pac-con-13-01-08
Autor:
Heather Flanagan-Steet, Margreet A. Wolfert, Frédéric Friscourt, Geert-Jan Boons, Ngalle Eric Mbua, Petr A. Ledin, Richard Steet
Publikováno v:
Journal of the American Chemical Society. 134:5381-5389
Although strain-promoted alkyne-azide cycloadditions (SPAAC) have found wide utility in biological and material sciences, the low polarity and limited water solubility of commonly used cyclooctynes represent a serious shortcoming. To address this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2da9f6120a328f59f9afa1d1d1aade
https://doi.org/10.1021/ja3002666
https://doi.org/10.1021/ja3002666
Autor:
Margreet A. Wolfert, Ngalle Eric Mbua, Geert-Jan Boons, Andrei Poloukhtine, Vladimir V. Popik
Publikováno v:
Journal of the American Chemical Society. 131:15769-15776
Phototriggering of the metal-free azide to acetylene cycloaddition reaction was achieved by masking the triple bond of dibenzocyclooctynes as cyclopropenone. Such masked cyclooctynes do not react with azides in the dark. Irradiation of cyclopropenone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737488efefb1679a2e74539ca601f4d4
https://doi.org/10.1021/ja9054096
https://doi.org/10.1021/ja9054096
Autor:
Heather Flanagan-Steet, Margreet A. Wolfert, Ngalle Eric Mbua, Geert-Jan Boons, Steven G. Johnson, Richard Steet
Niemann–Pick type C (NPC) disease is characterized by impaired cholesterol efflux from late endosomes and lysosomes and secondary accumulation of lipids. Although impaired trafficking of individual glycoproteins and glycolipids has been noted in NP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deeb89d9040660814c442d93d3546414
https://europepmc.org/articles/PMC3690855/
https://europepmc.org/articles/PMC3690855/
Publikováno v:
Chembiochem : a European journal of chemical biology. 12(12)
We have shown that 4-dibenzocyclooctynol (DIBO), which can easily be obtained by a streamlined synthesis approach, reacts exceptionally fast in the absence of a Cu(I) catalyst with azido-containing compounds to give stable triazoles. Chemical modific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2e865b8e436b830c80cdbb85fea9e0
https://pubmed.ncbi.nlm.nih.gov/21661087
https://pubmed.ncbi.nlm.nih.gov/21661087
Autor:
Vladimir V. Popik, Brian C. Sanders, Thomas J. Boltje, Ngalle Eric Mbua, Geert-Jan Boons, Petr A. Ledin, Frédéric Friscourt, Jun Guo, Selvanathan Arumugam
Although metal-free cycloadditions of cyclooctynes and azides to give stable 1,2,3-triazoles have found wide utility in chemical biology and material sciences, there is an urgent need for faster and more versatile bioorthogonal reactions. We have fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bed4cf655f5fbb787676d23c4b142f5
https://europepmc.org/articles/PMC3079482/
https://europepmc.org/articles/PMC3079482/