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Data from Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133+ Skin Cancer Stem Cells

Autor: Carter Van Waes, Zhong Chen, Martin Braun, Andrew Montemarano, Paul S. Meltzer, David W. Petersen, Steven K. Lee, Jamie Coupar, Weiping Chen, Nga Voong Hawk, Xin Xin Quan

Cancer stem–like cells are hypothesized to be the major tumor-initiating cell population of human cutaneous squamous cell carcinoma (cSCC), but the landscape of molecular alterations underpinning their signaling and cellular phenotypes as drug targ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45c6f9e05280d6dd0613f116054b2e06
https://doi.org/10.1158/1535-7163.c.6537792.v1

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Supplemental information, tables, and figures from Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133+ Skin Cancer Stem Cells

Autor: Carter Van Waes, Zhong Chen, Martin Braun, Andrew Montemarano, Paul S. Meltzer, David W. Petersen, Steven K. Lee, Jamie Coupar, Weiping Chen, Nga Voong Hawk, Xin Xin Quan

1. Supplementary Methods. 2. References. 3. Supplementary Table 1. Characteristics of human primary SCC samples. 4. Supplementary Table 2. Clinical characteristics of tumor samples used in different experimental platforms. 5. Supplemental Table 3. Ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088319a36dde1745960c88b5e4272db5
https://doi.org/10.1158/1535-7163.22504602

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Data from Transforming Growth Factor β Subverts the Immune System into Directly Promoting Tumor Growth through Interleukin-17

Autor: Lalage M. Wakefield, Jay A. Berzofsky, Scott Lonning, Mizuko Mamura, Aleksandra Michalowska, Arian Laurence, Yu-an Yang, Nga Voong, Helen Chae, Mi-Jin Kang, Masaki Terabe, Jeong-Seok Nam

Overexpression of the immunosuppressive cytokine transforming growth factor β (TGF-β) is one strategy that tumors have developed to evade effective immunesurveillance. Using transplantable models of breast and colon cancer, we made the unexpected f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::af293c3990301a378b40ef6c4b98435e
https://doi.org/10.1158/0008-5472.c.6497676

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Supplementary Figures 1-5, Table 1 from Transforming Growth Factor β Subverts the Immune System into Directly Promoting Tumor Growth through Interleukin-17

Autor: Lalage M. Wakefield, Jay A. Berzofsky, Scott Lonning, Mizuko Mamura, Aleksandra Michalowska, Arian Laurence, Yu-an Yang, Nga Voong, Helen Chae, Mi-Jin Kang, Masaki Terabe, Jeong-Seok Nam

Supplementary Figures 1-5, Table 1 from Transforming Growth Factor β Subverts the Immune System into Directly Promoting Tumor Growth through Interleukin-17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fee4304b16ead93c2cb3f57e762dd12
https://doi.org/10.1158/0008-5472.22375005.v1

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miR-181c regulates MCL1 and cell survival in GATA2 deficient cells

Autor: Stephenie Droll, Rui Chen, Dennis D. Hickstein, Meghan Corrigan-Cummins, Zhen Zhao, Layla M. Saleh, Emily Barber, Amy P. Hsu, Weixin Wang, Katherine R. Calvo, Donald C. Vinh, Nga Voong Hawk, Steven M. Holland, Vollter Anastas, Megan Trick

Publikováno v: Journal of Leukocyte Biology. 111:805-816

GATA2 is a transcription factor critical for hematopoiesis. Germline mutations in GATA binding protein 2 (GATA2) led to haploinsufficiency, severe cytopenias of multiple cell lineages, susceptibility to infections and strong propensity to develop mye

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7920f9b341e1fc94ede21555f31bf763
https://doi.org/10.1002/jlb.2a1220-824r

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Akademický článek

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Targeting Notch1 and IKKα Enhanced NF-κB Activation in CD133+ Skin Cancer Stem Cells

Autor: Nga Voong Hawk, Zhong Chen, David Petersen, Paul S. Meltzer, Carter Van Waes, Andrew Montemarano, Weiping Chen, Xin Xin Quan, Jamie Coupar, Martin Braun, Steven Lee

Publikováno v: Molecular Cancer Therapeutics. 17:2034-2048

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::79f351290ad95c7f5f9ea6ac1c7edca5
https://doi.org/10.1158/1535-7163.mct-17-0421

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Akademický článek

miR‐181c regulates MCL1 and cell survival in GATA2 deficient cells.

Autor: Wang, Weixin, Chen, Rui, Droll, Stephenie, Barber, Emily, Saleh, Layla, Corrigan‐Cummins, Meghan, Trick, Megan, Anastas, Vollter, Hawk, Nga Voong, Zhao, Zhen, Vinh, Donald C., Hsu, Amy, Hickstein, Dennis D., Holland, Steven M., Calvo, Katherine R.

Publikováno v: Journal of Leukocyte Biology; Apr2022, Vol. 111 Issue 4, p805-816, 12p

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