SCYL3, as a novel binding partner and regulator of ROCK2, promotes hepatocellular carcinoma progression.

Autor: Lei MML; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Leung CON; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Lau EYT; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong., Leung RWH; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Ma VWS; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Tong M; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Lu YY; Comprehensive Liver Cancer Center, The Fifth Medical Center of PLA General Hospital, Beijing, China., Huang CY; Comprehensive Liver Cancer Center, The Fifth Medical Center of PLA General Hospital, Beijing, China., Zhu QH; Department of Interventional Radiology and Oncology, Shunde Hospital, Southern Medical University, Shunde, China., Ng IOL; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Ma S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Lee TKW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong.; Research Institute for Future Food, The Hong Kong Polytechnic University, Hong Kong.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2022 Oct 13; Vol. 5 (1), pp. 100604. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2023).

Cancer stem cells: advances in biology and clinical translation-a Keystone Symposia report.

Autor: Cable J; PhD Science Writer, New York, New York., Pei D; CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou, China.; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; Guangzhou Regenerative Medicine and Health Guangdong Laboratory (GRMH-GDL), Guangzhou, China., Reid LM; Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina., Wang XW; Laboratory of Human Carcinogenesis, and Liver Cancer Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Bhatia S; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York., Karras P; Laboratory for Molecular Cancer Biology, Center for Cancer Biology and Laboratory for Molecular Cancer Biology, Department of Oncology, Leuven, Belgium., Melenhorst JJ; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center and Department of Pathology & Laboratory Medicine, Perelman School of Medicine and Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, Pennsylvania., Grompe M; Department of Molecular and Medical Genetics, Department of Pediatrics, and Oregon Stem Cell Center, Oregon Health & Science University, Portland, Oregon., Lathia JD; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute and Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland Clinic, Cleveland, Ohio., Song E; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center and Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Bioland Laboratory; Program of Molecular Medicine, Zhongshan School of Medicine, Sun Yat-Sen University; and Fountain-Valley Institute for Life Sciences, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China., Kuo CJ; Division of Hematology, Department of Medicine, Stanford University, Stanford, California., Zhang N; Translational Cancer Research Center, Peking University First Hospital, Beijing, China., White RM; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Ma SK; School of Biomedical Sciences and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Ma L; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Chin YR; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China., Shen MM; Departments of Medicine, Genetics and Development, Urology, and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York., Ng IOL; Department of Pathology and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Kaestner KH; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Zhou L; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, Hong Kong., Sikandar S; Institute for the Biology of Stem Cells, University of California, Santa Cruz, Santa Cruz, California., Schmitt CA; Charité - Universitätsmedizin Berlin, Hematology/Oncology, and Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, and Johannes Kepler University, Kepler Universitätsklinikum, Hematology/Oncology, Linz, Austria., Guo W; Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, Pennsylvania., Wong CC; Department of Pathology and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Ji J; MOE Key Laboratory of Biosystems Homeostasis & Protection, and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China., Tang DG; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, and Experimental Therapeutics (ET) Graduate Program, University at Buffalo, Buffalo, New York., Dubrovska A; OncoRay National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Partner Site Dresden, Heidelberg, Germany., Yang C; Neuro-Oncology Branch, National Cancer Institute, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland., Wiedemeyer WR; AbbVie, Inc., Lake Bluff, Illinois., Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center for Cancer Stem Cell Research, Stanford University, Stanford, California.

Publikováno v: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2021 Dec; Vol. 1506 (1), pp. 142-163. Date of Electronic Publication: 2021 Nov 30.

Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells.

Autor: Xiao, Yang^1,2 (AUTHOR), Tao, Ping³ (AUTHOR), Zhang, Keke¹ (AUTHOR), Chen, Liuyan¹ (AUTHOR), Lv, Jinyu¹ (AUTHOR), Chen, Zhiwei³ (AUTHOR), He, Lu⁴ (AUTHOR), Jia, Hongling⁵ (AUTHOR), Sun, Jian³ (AUTHOR), Cao, Mingrong³ (AUTHOR), Hong, Jian^1,3 (AUTHOR) hongjian7@jnu.edu.cn, Qu, Chen¹ (AUTHOR) Cheyne1988@outlook.com

Publikováno v: Molecular Cancer. 11/21/2024, Vol. 23 Issue 1, p1-17. 17p.

The roles and mechanisms of miRNA in HBV-HCC carcinogenesis: Why no therapeutic agents after 30 years?

Autor: SARTORIUS, KURT^1,2,3 (AUTHOR) kurt.sartorius@wits.ac.za, SARTORIUS, BENN⁴ (AUTHOR), WINKLER, CHERIE⁵ (AUTHOR), CHUTURGOON, ANIL² (AUTHOR), KRAMVIS, ANNA¹ (AUTHOR), AN, PING⁵ (AUTHOR), ZHANG, WEIGANG⁶ (AUTHOR), LU, YUNJIE^3,6,7 (AUTHOR) yj0001@suda.edu.cn

Publikováno v: Biocell. 2024, Vol. 48 Issue 11, p1543-1567. 25p.

Corrigendum to "NRF2/SHH signaling cascade promotes tumor-initiating cell lineage and drug resistance in hepatocellular carcinoma" [Canc. Lett. 476 (2020) 48-56].

Autor: Leung HW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Lau EYT; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong., Leung CON; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Lei MML; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Mok EHK; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Ma VWS; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong., Cho WCS; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong., Ng IOL; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Yun JP; Department of Pathology, Sun Yat Sen University Cancer Center, China., Cai SH; Department of Pathology, Sun Yat Sen University Cancer Center, China., Yu HJ; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Hong Kong., Ma S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Lee TKW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong. Electronic address: terence.kw.lee@polyu.edu.hk.

Publikováno v: Cancer letters [Cancer Lett] 2021 Feb 28; Vol. 499, pp. 2. Date of Electronic Publication: 2020 Jun 17.