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Retrospective analysis of Schlafen11 (SLFN11) to predict the outcomes to therapies affecting the DNA damage response.

Autor: Willis SE; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Winkler C; Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK., Roudier MP; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Baird T; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Marco-Casanova P; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Jones EV; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Rowe P; GMD, Oncology R&D, AstraZeneca, Macclesfield, UK., Rodriguez-Canales J; Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Angell HK; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Ng FSL; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Waring PM; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Hodgson D; Translational Medicine, Oncology R&D, AstraZeneca, Boston, MA, USA., Ledermann JA; Cancer Research UK and UCL Cancer Trials Centre, UCL Cancer Institute, London, UK., Weberpals JI; Ottawa Hospital Research Institute, Ottawa, ON, Canada., Dean E; Clinical, Oncology R&D, AstraZeneca, Cambridge, UK., Harrington EA; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Barrett JC; Translational Medicine, Oncology R&D, AstraZeneca, Gaithersburg, MD, USA., Pierce AJ; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK., Leo E; Bioscience, Oncology R&D, AstraZeneca, Cambridge, UK., Jones GN; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK. gemma.jones@astrazeneca.com.

Publikováno v: British journal of cancer [Br J Cancer] 2021 Dec; Vol. 125 (12), pp. 1666-1676. Date of Electronic Publication: 2021 Oct 18.

Actively evolving subglacial conduits and eskers initiate ice shelf channels at an Antarctic grounding line.

Autor: Drews R; Université libre de Bruxelles, Laboratoire de Glaciologie, Avenue F.D. Roosevelt 50, Brussels 1050, Belgium.; Bavarian Academy of Sciences and Humanities, Glaziologie, Alfons-Goppel-Str. 11, Munich 80539, Germany., Pattyn F; Université libre de Bruxelles, Laboratoire de Glaciologie, Avenue F.D. Roosevelt 50, Brussels 1050, Belgium., Hewitt IJ; University of Oxford, Mathematical Institute, Woodstock Road, Oxford OX26GG, UK., Ng FSL; The University of Sheffield, Department of Geography, Winter street, Sheffield S102TN, UK., Berger S; Université libre de Bruxelles, Laboratoire de Glaciologie, Avenue F.D. Roosevelt 50, Brussels 1050, Belgium., Matsuoka K; Norwegian Polar Institute, Fram Centre 9296 Tromsø, Norway., Helm V; Alfred Wegener Institute, Am Alten Hafen 26, Bremerhaven 27568, Germany., Bergeot N; Royal Observatory of Belgium, Av. Circulaire 3, Brussels 1180, Belgium., Favier L; Université libre de Bruxelles, Laboratoire de Glaciologie, Avenue F.D. Roosevelt 50, Brussels 1050, Belgium., Neckel N; Alfred Wegener Institute, Am Alten Hafen 26, Bremerhaven 27568, Germany.

Publikováno v: Nature communications [Nat Commun] 2017 May 09; Vol. 8, pp. 15228. Date of Electronic Publication: 2017 May 09.