SCYL3, as a novel binding partner and regulator of ROCK2, promotes hepatocellular carcinoma progression.

Autor: Lei MML; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Leung CON; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Lau EYT; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong., Leung RWH; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Ma VWS; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong., Tong M; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong., Lu YY; Comprehensive Liver Cancer Center, The Fifth Medical Center of PLA General Hospital, Beijing, China., Huang CY; Comprehensive Liver Cancer Center, The Fifth Medical Center of PLA General Hospital, Beijing, China., Zhu QH; Department of Interventional Radiology and Oncology, Shunde Hospital, Southern Medical University, Shunde, China., Ng IOL; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Ma S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Lee TKW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong.; Research Institute for Future Food, The Hong Kong Polytechnic University, Hong Kong.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong.

Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2022 Oct 13; Vol. 5 (1), pp. 100604. Date of Electronic Publication: 2022 Oct 13 (Print Publication: 2023).

Cancer stem cells: advances in biology and clinical translation-a Keystone Symposia report.

Autor: Cable J; PhD Science Writer, New York, New York., Pei D; CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou, China.; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.; Guangzhou Regenerative Medicine and Health Guangdong Laboratory (GRMH-GDL), Guangzhou, China., Reid LM; Department of Cell Biology and Physiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina., Wang XW; Laboratory of Human Carcinogenesis, and Liver Cancer Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland., Bhatia S; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York., Karras P; Laboratory for Molecular Cancer Biology, Center for Cancer Biology and Laboratory for Molecular Cancer Biology, Department of Oncology, Leuven, Belgium., Melenhorst JJ; Glioblastoma Translational Center of Excellence, The Abramson Cancer Center and Department of Pathology & Laboratory Medicine, Perelman School of Medicine and Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, Pennsylvania., Grompe M; Department of Molecular and Medical Genetics, Department of Pediatrics, and Oregon Stem Cell Center, Oregon Health & Science University, Portland, Oregon., Lathia JD; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute and Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland Clinic, Cleveland, Ohio., Song E; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Medical Research Center and Breast Tumor Center, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.; Bioland Laboratory; Program of Molecular Medicine, Zhongshan School of Medicine, Sun Yat-Sen University; and Fountain-Valley Institute for Life Sciences, Guangzhou Institute of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China., Kuo CJ; Division of Hematology, Department of Medicine, Stanford University, Stanford, California., Zhang N; Translational Cancer Research Center, Peking University First Hospital, Beijing, China., White RM; Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, New York, New York., Ma SK; School of Biomedical Sciences and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong., Ma L; Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland., Chin YR; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China., Shen MM; Departments of Medicine, Genetics and Development, Urology, and Systems Biology, Herbert Irving Comprehensive Cancer Center, Columbia University College of Physicians and Surgeons, New York, New York., Ng IOL; Department of Pathology and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Kaestner KH; Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Zhou L; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, Hong Kong., Sikandar S; Institute for the Biology of Stem Cells, University of California, Santa Cruz, Santa Cruz, California., Schmitt CA; Charité - Universitätsmedizin Berlin, Hematology/Oncology, and Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, and Johannes Kepler University, Kepler Universitätsklinikum, Hematology/Oncology, Linz, Austria., Guo W; Department of Biology, School of Arts & Sciences, University of Pennsylvania, Philadelphia, Pennsylvania., Wong CC; Department of Pathology and State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Ji J; MOE Key Laboratory of Biosystems Homeostasis & Protection, and Zhejiang Provincial Key Laboratory for Cancer Molecular Cell Biology, Life Sciences Institute, Zhejiang University, Hangzhou, China., Tang DG; Department of Pharmacology & Therapeutics, Roswell Park Comprehensive Cancer Center, and Experimental Therapeutics (ET) Graduate Program, University at Buffalo, Buffalo, New York., Dubrovska A; OncoRay National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.; Helmholtz-Zentrum Dresden-Rossendorf, Institute of Radiooncology-OncoRay, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany.; National Center for Tumor Diseases (NCT), Partner Site Dresden, Heidelberg, Germany., Yang C; Neuro-Oncology Branch, National Cancer Institute, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland., Wiedemeyer WR; AbbVie, Inc., Lake Bluff, Illinois., Weissman IL; Institute for Stem Cell Biology and Regenerative Medicine, Ludwig Center for Cancer Stem Cell Research, Stanford University, Stanford, California.

Publikováno v: Annals of the New York Academy of Sciences [Ann N Y Acad Sci] 2021 Dec; Vol. 1506 (1), pp. 142-163. Date of Electronic Publication: 2021 Nov 30.

RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2.

Autor: Wang X; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Pathology, The University of Hong Kong, Hong Kong, China., Wang J; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Tsui YM; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Pathology, The University of Hong Kong, Hong Kong, China., Shi C; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Wang Y; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, China., Zhang X; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Pathology, The University of Hong Kong, Hong Kong, China., Yan Q; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Chen M; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China., Jiang C; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State Key Laboratory of Oncology in Southern China, Sun Yat-Sen University Cancer Center, Guangzhou, China.; Department of Pathology, Sun Yat-Sen University Cancer Center, Guangzhou, China., Yuan YF; State Key Laboratory of Oncology in Southern China, Sun Yat-Sen University Cancer Center, Guangzhou, China., Wong CM; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Pathology, The University of Hong Kong, Hong Kong, China., Liu M; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China., Feng ZY; Department of General Surgery, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China., Chen H; Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China., Ng IOL; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China.; Department of Pathology, The University of Hong Kong, Hong Kong, China., Jiang L; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. jlx12120@rjh.com.cn.; Department of General Surgery, Ruijin Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China. jlx12120@rjh.com.cn., Guan XY; Department of Clinical Oncology, The University of Hong Kong, Hong Kong, China. xyguan@hku.hk.; State key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, China. xyguan@hku.hk.

Publikováno v: Nature communications [Nat Commun] 2021 Mar 09; Vol. 12 (1), pp. 1518. Date of Electronic Publication: 2021 Mar 09.

The interplay of UBE2T and Mule in regulating Wnt/β-catenin activation to promote hepatocellular carcinoma progression.

Autor: Ho NPY; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong., Leung CON; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong., Wong TL; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong., Lau EYT; Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, Hong Kong., Lei MML; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong., Mok EHK; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong., Leung HW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong., Tong M; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong., Ng IOL; Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, Hong Kong., Yun JP; Department of Pathology, Sun Yat Sen University Cancer Center, Guangzhou, China., Ma S; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.; State Key Laboratory of Liver Research, The University of Hong Kong, Hong Kong, Hong Kong., Lee TKW; Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, Hong Kong. terence.kw.lee@polyu.edu.hk.; State Key Laboratory of Chemical Biology and Drug Discovery, The Hong Kong Polytechnic University, Hong Kong, Hong Kong. terence.kw.lee@polyu.edu.hk.

Publikováno v: Cell death & disease [Cell Death Dis] 2021 Feb 01; Vol. 12 (2), pp. 148. Date of Electronic Publication: 2021 Feb 01.

PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma

Autor: Ng, IOL, Lo, CLR, Leung, CON, Wong, CCL, Fan, DNY, Kai, AKL, Tung, EKK, Xu, IMJ

published_or_final_version

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______961::22c18721ce24d717c1c81ecb0a980605
http://hdl.handle.net/10722/212076