Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV.

Autor: Ng'uni TL; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa., Musale V; Emory-University of Georgia, Center of Excellence of Influenza Research and Surveillance (CEIRS), Lusaka, Zambia.; Center for Family Health Research in Zambia (CFHRZ), formerly Zambia Emory HIV Research Project (ZEHRP), Lusaka, Zambia., Nkosi T; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa., Mandolo J; Infection and Immunity Research Group, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi., Mvula M; Infection and Immunity Research Group, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi., Michelo C; Emory-University of Georgia, Center of Excellence of Influenza Research and Surveillance (CEIRS), Lusaka, Zambia.; Center for Family Health Research in Zambia (CFHRZ), formerly Zambia Emory HIV Research Project (ZEHRP), Lusaka, Zambia., Karim F; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa., Moosa MYS; Human Immunodeficiency Virus (HIV) Pathogenesis Program, School of Laboratory Medicine and Medical Sciences, University of KwaZulu Natal, Durban, South Africa., Khan K; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa., Jambo KC; Infection and Immunity Research Group, Malawi-Liverpool-Wellcome Trust Clinical Research Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, United Kingdom., Hanekom W; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom., Sigal A; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa., Kilembe W; Emory-University of Georgia, Center of Excellence of Influenza Research and Surveillance (CEIRS), Lusaka, Zambia.; Center for Family Health Research in Zambia (CFHRZ), formerly Zambia Emory HIV Research Project (ZEHRP), Lusaka, Zambia., Ndhlovu ZM; Africa Health Research Institute (AHRI), Nelson R. Mandela School of Medicine, Durban, South Africa.; Human Immunodeficiency Virus (HIV) Pathogenesis Program, School of Laboratory Medicine and Medical Sciences, University of KwaZulu Natal, Durban, South Africa.; Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, MA, United States.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Jan 26; Vol. 14, pp. 1291048. Date of Electronic Publication: 2024 Jan 26 (Print Publication: 2023).