Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study

Autor: MacKay, James W., Nezhad, Faezeh Sanaei, Rifai, Tamam, Kaggie, Joshua D., Naish, Josephine H., Roberts, Caleb, Graves, Martin J., Waterton, John C., Janiczek, Robert L., Roberts, Alexandra R., McCaskie, Andrew, Gilbert, Fiona J., Parker, Geoff J. M.

Objectives: Evaluate test-retest repeatability, ability to discriminate between osteoarthritic and healthy participants, and sensitivity to change over 6 months, of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) biomarkers in knee OA.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea227f9849e5a539516c5619bef4e8c
https://www.repository.cam.ac.uk/handle/1810/318465

Quantification of GABA, Glutamate and Glutamine in a single Measurement at 3T using GABA-edited MEGA-PRESS

Autor: Nezhad, Faezeh Sanaei, Anton, Adriana, Michou, Emilia, Jung, JeYoung, Parkes, Laura M., Williams, Stephen R.

Publikováno v: Nezhad, F S, Anton, A, Michou, E, Jung, J, Parkes, L M & Williams, S R 2018, ' Quantification of GABA, Glutamate and Glutamine in a single Measurement at 3T using GABA-edited MEGA-PRESS ', NMR in Biomedicine, vol. 31, no. 1, e3847 . https://doi.org/10.1002/nbm.3847
Sanaei Nezhad, F, Anton, A, Michou, E, Jung, J, Parkes, L M & Williams, S R 2018, ' Quantification of GABA, glutamate and glutamine in a single measurement at 3 T using GABA-edited MEGA-PRESS ' NMR in Biomedicine, vol 31, no. 1 . DOI: 10.1002/nbm.3847

γ-Aminobutyric acid (GABA) and glutamate (Glu), major neurotransmitters in the brain, are recycled through glutamine (Gln). All three metabolites can be measured by magnetic resonance spectroscopy in vivo, although GABA measurement at 3 T requires a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7ff0198e37d4e7073478debc40f3e368
https://www.research.manchester.ac.uk/portal/en/publications/quantification-of-gaba-glutamate-and-glutamine-in-a-single-measurement-at-3t-using-gabaedited-megapress(8d8e0437-3665-4fd6-a27b-aceebfeb2762).html

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Dynamic contrast-enhanced MRI of synovitis in knee osteoarthritis: repeatability, discrimination and sensitivity to change in a prospective experimental study.

Autor: MacKay JW; Department of Radiology, University of Cambridge, Cambridge, UK. james.w.mackay@uea.ac.uk.; Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UY, UK. james.w.mackay@uea.ac.uk., Nezhad FS; Bioxydyn Limited, Manchester, UK., Rifai T; Department of Radiology, Norfolk & Norwich University Hospital, Norwich, UK., Kaggie JD; Department of Radiology, University of Cambridge, Cambridge, UK., Naish JH; Bioxydyn Limited, Manchester, UK., Roberts C; Bioxydyn Limited, Manchester, UK., Graves MJ; Department of Radiology, University of Cambridge, Cambridge, UK., Waterton JC; Bioxydyn Limited, Manchester, UK.; Centre for Imaging Sciences, Division of Informatics Imaging & Data Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK., Janiczek RL; Clinical Imaging, GlaxoSmithKline, London, UK., Roberts AR; Clinical Imaging, GlaxoSmithKline, London, UK.; Antaros Medical, Uppsala, Sweden., McCaskie A; Division of Trauma & Orthopaedics, Department of Surgery, University of Cambridge, Cambridge, UK., Gilbert FJ; Department of Radiology, University of Cambridge, Cambridge, UK., Parker GJM; Bioxydyn Limited, Manchester, UK.; Centre for Medical Image Computing, Department of Medical Physics and Biomedical Engineering, University College London, London, UK.

Publikováno v: European radiology [Eur Radiol] 2021 Aug; Vol. 31 (8), pp. 5746-5758. Date of Electronic Publication: 2021 Feb 16.