Zobrazeno 1 - 10
of 466
pro vyhledávání: '"Nezam H, Afdhal"'
Autor:
Mohammad Honarvar, Julio Lobo, Caitlin Schneider, Samuel Klein, Gordon I. Smith, Rohit Loomba, Alnoor Ramji, Tarek Hassanein, Eric M. Yoshida, Emily Pang, Michael P. Curry, Nezam H. Afdhal
Publikováno v:
WFUMB Ultrasound Open, Vol 2, Iss 2, Pp 100061- (2024)
Introduction: As prevalence of patients with steatotic liver diseases increases throughout the world, it is necessary to have accurate and accessible methods to estimate liver fat content. Using quantitative ultrasound parameters, such as attenuation
Externí odkaz:
https://doaj.org/article/7de839a8c75b49dab257ace0a800fd48
Autor:
Nezam H, Afdhal, Walter, Ageno, Marcello, Bianchini, Annabel, Blasi, Stephen H, Caldwell, Mark, Callaway, Andres, Cardenas, Sarwa, Darwish Murad, Andrea, De Gottardi, Lesley, De Pietri, Emmanuelle, De Raucourt, Alessandra, Dell'Era, Alban, Denys, Laure, Elkrief, Juan-Carlos, Garcia-Pagan, Guadalupe, Garcia-Tsao, Alexander, Gatt, Edoardo G, Giannini, Rita, Golfieri, Charles S, Greenberg, Virginia, Hernández-Gea, Mathis, Heydtmann, Nicolas M, Intagliata, Patrick S, Kamath, Will, Lester, Maria, Magnusson, James, Neuberger, Patrick G, Northup, G, O'Leary Jacqueline, Heather, Patton, Markus, Peck-Radosavljevic, Anjana, Pillai, Aurélie, Plessier, Pierre-Emmanuel, Rautou, Cristina, Ripoll, Lara N, Roberts, Ammar, Sarwar, Marco, Senzolo, Akash, Shukla, Paolo, Simioni, Douglas A, Simonetto, Ashwani K, Singal, Robin, Soto, Jonathan G, Stine, Elliot B, Tapper, Dominique, Thabut, Jecko, Thachil, Dana, Tomescu, Dhiraj, Tripathi, Emmanuel A, Tsochatzis, Erica, Villa, Dominique, Valla, Riescher-Tuczkiewicz, Alix, Caldwell, Stephen H., Kamath, Patrick S., Villa, Erica, Rautou, Pierre-Emmanuel
Publikováno v:
In JHEP Reports March 2024 6(3)
Autor:
Michael P. Curry, Edward Tam, Caitlin Schneider, Noha Abdelgelil, Tarek Hassanien, Nezam H. Afdhal
Publikováno v:
International Journal of Hepatology, Vol 2024 (2024)
Background and Aims. Nonalcoholic fatty liver disease is the leading cause of chronic liver disease globally and can progress to cirrhosis, liver failure, and liver cancer. Current AASLD, AGA, and ADA guidelines recommend assessment for liver fibrosi
Externí odkaz:
https://doaj.org/article/7d209f4e7a0a407aaafa05a669a02fa5
Autor:
Calvin Q. Pan, Nezam H. Afdhal, Victor Ankoma‐Sey, Ho Bae, Michael P. Curry, Douglas Dieterich, Lynn Frazier, Andrew Frick, Hie‐Won Hann, W. Ray Kim, Paul Kwo, Scott Milligan, Myron J. Tong, K. Rajender Reddy
Publikováno v:
Hepatology Communications, Vol 6, Iss 8, Pp 1881-1894 (2022)
Abstract Real‐world data are limited on tenofovir alafenamide (TAF). We aimed to study TAF real‐world outcomes with other first‐line regimens for chronic hepatitis B (CHB). We enrolled patients with CHB from 10 centers retrospectively and follo
Externí odkaz:
https://doaj.org/article/c069a6f091ce4455a5cb4d4d17687cc2
Autor:
Joana Vieira Barbosa, Scott Milligan, Andrew Frick, Jeremy Broestl, Zobair Younossi, Nezam H. Afdhal, Michelle Lai
Publikováno v:
Hepatology Communications, Vol 6, Iss 4, Pp 765-779 (2022)
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and its prevalence continues to rise. Fibrosis‐4 index (FIB‐4) has been shown to be a prognostic marker of liver‐related outcomes in patients with NAFL
Externí odkaz:
https://doaj.org/article/554fe686a6b545b09d479fe7dd7bf71f
Autor:
Ghideon Ezaz, Hirsh D. Trivedi, Margery A. Connelly, Claudia Filozof, Kellie Howard, Mark L.Parrish, Misung Kim, Mark A. Herman, Imad Nasser, Nezam H. Afdhal, Z. Gordon Jiang, Michelle Lai
Publikováno v:
Hepatology Communications, Vol 4, Iss 5, Pp 670-680 (2020)
Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous disease driven by genetic and environmental factors. MicroRNAs (miRNAs) serve as pleiotropic post‐transcriptional regulators of cellular pathways. Although several miRNAs have been associa
Externí odkaz:
https://doaj.org/article/3e31e44a9bf34567b3f367787a2d4008
Autor:
Christopher J. Danford, Margery A. Connelly, Irina Shalaurova, Misung Kim, Mark A. Herman, Imad Nasser, James D. Otvos, Nezam H. Afdhal, Z. Gordon Jiang, Michelle Lai
Publikováno v:
Hepatology Communications, Vol 2, Iss 12, Pp 1467-1478 (2018)
Nonalcoholic fatty liver disease (NAFLD) is a complex disease dictated by both genetic and environmental factors. While insulin resistance (IR) is a key pathogenic driver, two common genetic variants in patatin‐like phospholipase domain containing
Externí odkaz:
https://doaj.org/article/67bd652349954a62aa0fb703e5769fbd
Autor:
Eric Lawitz, Manuel Romero-Gómez, Quentin M. Anstee, Stephen A. Harrison, Catherine Jia, Zobair M. Younossi, Chuhan Chung, Zachary Goodman, Robert P. Myers, Ryan S Huss, Michael Trauner, Vincent Wai-Sun Wong, Andrew J. Muir, Takeshi Okanoue, Jaime Bosch, D. Ding, Nezam H. Afdhal, Manal F. Abdelmalek, Ling Han, Arun J. Sanyal
Publikováno v:
Sanyal, Arun J; Anstee, Quentin M; Trauner, Michael; Lawitz, Eric J; Abdelmalek, Manal F; Ding, Dora; Han, Ling; Jia, Catherine; Huss, Ryan S; Chung, Chuhan; Wong, Vincent Wai-Sun; Okanoue, Takeshi; Romero-Gomez, Manuel; Muir, Andrew J; Afdhal, Nezam H; Bosch, Jaime; Goodman, Zachary; Harrison, Stephen A; Younossi, Zobair M and Myers, Robert P (2022). Cirrhosis Regression is Associated with Improved Clinical Outcomes in Patients with Nonalcoholic Steatohepatitis. Hepatology, 75(5), pp. 1235-1246. Wiley 10.1002/hep.32204
[Background and Aims] Surrogate endpoints that predict complications are necessary for assessment and approval of NASH therapies. We assessed associations between histologic and noninvasive tests (NITs) of fibrosis with liver‐related complications
Autor:
Joana, Vieira Barbosa, Scott, Milligan, Andrew, Frick, Jeremy, Broestl, Zobair, Younossi, Nezam H, Afdhal, Michelle, Lai
Publikováno v:
Hepatology Communications. 6:765-779
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide, and its prevalence continues to rise. Fibrosis-4 index (FIB-4) has been shown to be a prognostic marker of liver-related outcomes in patients with NAFLD. We
Autor:
Don C. Rockey, Andrew H. Beck, Murray B. Resnick, Nezam H. Afdhal, Michael Christopher Montalto, Oscar Carrasco-Zevallos, Catherine Jia, Zachary Goodman, Harsha Pokkalla, Mitchell L. Shiffman, Zahil Shanis, Ling Han, Jaime Bosch, Manal F. Abdelmalek, Arun J. Sanyal, Quang Huy Le, Chuhan Chung, Robert P. Myers, Ilan Wapinski, Stephen A. Harrison, Dinkar Juyal
Publikováno v:
Bosch, Jaime; Chung, Chuhan; Carrasco-Zevallos, Oscar M; Harrison, Stephen A; Abdelmalek, Manal F; Shiffman, Mitchell L; Rockey, Don C; Shanis, Zahil; Juyal, Dinkar; Pokkalla, Harsha; Le, Quang Huy; Resnick, Murray; Montalto, Michael; Beck, Andrew H; Wapinski, Ilan; Han, Ling; Jia, Catherine; Goodman, Zachary; Afdhal, Nezam; Myers, Robert P; ... (2021). A Machine Learning Approach to Liver Histological Evaluation Predicts Clinically Significant Portal Hypertension in NASH Cirrhosis. Hepatology, 74(6), pp. 3146-3160. Wiley 10.1002/hep.32087
BACKGROUND AND AIMS The hepatic venous pressure gradient (HVPG) is the standard for estimating portal pressure but requires expertise for interpretation. We hypothesized that HVPG could be extrapolated from liver histology using a machine learning (M