Výsledky vyhledávání - "Neysa Garner"

Supplementary Figure 5 from In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

Autor: Alan J. Korman, Mark J. Selby, Diann Blanset, R. Todd Bunch, Heidi Leblanc, Neysa Garner, Susan Wong, Sujata Singh, Mohan Srinivasan, Michelle Kuhne, Yi Wu, Candy Garcia, Diane Feingersh, Haichun Huang, Xi-Tao Wang, Minhua Han, Kent B. Thudium, Changyu Wang

PDF file - 25K, Figure S5. Effect of nivolumab on CD8+ T-cell subsets and DCs in PBMCs from nivolumab-treated cynomolgus monkeys.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3afeb590b18bc2205b3661f639ca33c
https://doi.org/10.1158/2326-6066.22537295

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Supplementary Figure 2 from In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

PDF file - 376K, Figure S2. Epitope of nivolumab on human PD-1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b853d4530e61228723451974fc3c28ae
https://doi.org/10.1158/2326-6066.22537304.v1

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Supplementary Figure Legends from In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

PDF file - 400K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77e844640ae1ffeb1fc6f84395d28dbf
https://doi.org/10.1158/2326-6066.22537292

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Supplementary Figure 3 from In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

PDF file - 22K, Figure S3. Nivolumab inhibits PD-1 interaction with PD-L1 and PD-L2.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171e64e5c6eda8b06e46db9ba0ec0274
https://doi.org/10.1158/2326-6066.22537301.v1

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Supplementary Figure 4 from In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

PDF file - 239K, Figure S4. A, Expression of PD-1 in CD4 T cells during mixed lymphocyte reaction (MLR). B, Expression of PD-1 and PD-L1 during stimulation of peripheral blood mononuclear cells (PBMC) by superantigen SEB.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c943bf1ae098479376b53e375616e33
https://doi.org/10.1158/2326-6066.22537298

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Supplementary Figure 1 from In Vitro Characterization of the Anti-PD-1 Antibody Nivolumab, BMS-936558, and In Vivo Toxicology in Non-Human Primates

PDF file - 72K, Figure S1. Binding of nivolumab to human T cells.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::024e1c67bc7683d5c8b6c266d2f11e3d
https://doi.org/10.1158/2326-6066.22537307.v1

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Developmental Diethylstilbestrol Exposure Alters Genetic Pathways of Uterine Cytodifferentiation

Autor: Jussi Vuoristo, John A. McLachlan, Wei-Wei Huang, Liang Ma, Tung-Chin Chiang, Neysa Garner, Yan Yin, Qun Bi

Publikováno v: Molecular Endocrinology. 19:669-682

The formation of a simple columnar epithelium in the uterus is essential for implantation. Perturbation of this developmental process by exogenous estrogen, such as diethylstilbestrol (DES), results in uterine metaplasia that contributes to infertili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9c9b713052573efe2042d56495bfbd
https://doi.org/10.1210/me.2004-0155

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In vitro characterization of the anti-PD-1 antibody nivolumab, BMS-936558, and in vivo toxicology in non-human primates

Autor: Mohan Srinivasan, R. Todd Bunch, Haichun Huang, Susan Wong, Heidi N. Leblanc, Michelle Kuhne, Kent B. Thudium, Minhua Han, Sujata Singh, Xi-Tao Wang, Yi Wu, Diann Blanset, Diane Feingersh, Neysa Garner, Changyu Wang, Alan J. Korman, Mark J. Selby, Candy Garcia

Publikováno v: Cancer immunology research. 2(9)

The programmed death-1 (PD-1) receptor serves as an immunologic checkpoint, limiting bystander tissue damage and preventing the development of autoimmunity during inflammatory responses. PD-1 is expressed by activated T cells and downmodulates T-cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec4afbbd327a9b5cf6c2e22093de84e
https://pubmed.ncbi.nlm.nih.gov/24872026

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