Novel risk loci for COVID-19 hospitalization among admixed American populations

Autor: Silvia Diz-de Almeida, Raquel Cruz, Andre D Luchessi, José M Lorenzo-Salazar, Miguel López de Heredia, Inés Quintela, Rafaela González-Montelongo, Vivian Nogueira Silbiger, Marta Sevilla Porras, Jair Antonio Tenorio Castaño, Julian Nevado, Jose María Aguado, Carlos Aguilar, Sergio Aguilera-Albesa, Virginia Almadana, Berta Almoguera, Nuria Alvarez, Álvaro Andreu-Bernabeu, Eunate Arana-Arri, Celso Arango, María J Arranz, Maria-Jesus Artiga, Raúl C Baptista-Rosas, María Barreda- Sánchez, Moncef Belhassen-Garcia, Joao F Bezerra, Marcos AC Bezerra, Lucía Boix-Palop, María Brion, Ramón Brugada, Matilde Bustos, Enrique J Calderón, Cristina Carbonell, Luis Castano, Jose E Castelao, Rosa Conde-Vicente, M Lourdes Cordero-Lorenzana, Jose L Cortes-Sanchez, Marta Corton, M Teresa Darnaude, Alba De Martino-Rodríguez, Victor del Campo-Pérez, Aranzazu Diaz de Bustamante, Elena Domínguez-Garrido, Rocío Eirós, María Carmen Fariñas, María J Fernandez-Nestosa, Uxía Fernández-Robelo, Amanda Fernández-Rodríguez, Tania Fernández-Villa, Manuela Gago-Dominguez, Belén Gil-Fournier, Javier Gómez-Arrue, Beatriz González Álvarez, Fernan Gonzalez Bernaldo de Quirós, Anna González-Neira, Javier González-Peñas, Juan F Gutiérrez-Bautista, María José Herrero, Antonio Herrero-Gonzalez, María A Jimenez-Sousa, María Claudia Lattig, Anabel Liger Borja, Rosario Lopez-Rodriguez, Esther Mancebo, Caridad Martín-López, Vicente Martín, Oscar Martinez-Nieto, Iciar Martinez-Lopez, Michel F Martinez-Resendez, Angel Martinez-Perez, Juliana F Mazzeu, Eleuterio Merayo Macías, Pablo Minguez, Victor Moreno Cuerda, Silviene F Oliveira, Eva Ortega-Paino, Mara Parellada, Estela Paz-Artal, Ney PC Santos, Patricia Pérez-Matute, Patricia Perez, M Elena Pérez-Tomás, Teresa Perucho, Mellina Pinsach-Abuin, Guillermo Pita, Ericka N Pompa-Mera, Gloria L Porras-Hurtado, Aurora Pujol, Soraya Ramiro León, Salvador Resino, Marianne R Fernandes, Emilio Rodríguez-Ruiz, Fernando Rodriguez-Artalejo, José A Rodriguez-Garcia, Francisco Ruiz-Cabello, Javier Ruiz-Hornillos, Pablo Ryan, José Manuel Soria, Juan Carlos Souto, Eduardo Tamayo, Alvaro Tamayo-Velasco, Juan Carlos Taracido-Fernandez, Alejandro Teper, Lilian Torres-Tobar, Miguel Urioste, Juan Valencia-Ramos, Zuleima Yáñez, Ruth Zarate, Itziar de Rojas, Agustín Ruiz, Pascual Sánchez, Luis Miguel Real, SCOURGE Cohort Group, Encarna Guillen-Navarro, Carmen Ayuso, Esteban Parra, José A Riancho, Augusto Rojas-Martinez, Carlos Flores, Pablo Lapunzina, Ángel Carracedo

Publikováno v: eLife, Vol 13 (2024)

The genetic basis of severe COVID-19 has been thoroughly studied, and many genetic risk factors shared between populations have been identified. However, reduced sample sizes from non-European groups have limited the discovery of population-specific

Externí odkaz: https://doaj.org/article/011994bb968f4b9ab2fc855d5fdf6178

Analysis of 12 variants in the development of gastric and colorectal cancers

Autor: Marianne Rodrigues Fernandes, Danielle F Costa, Ândrea Kely Campos Ribeiro dos Santos, Paulo Pimentel Assumpção, Roberta Borges Andrade, Ney Pc Santos, Esdras E. B. Pereira, Darlen Cardoso de Carvalho, Giovanna C Cavalcante, Marcos At Amador, Sidney Santos, André Mauricio Ribeiro dos Santos

Publikováno v: World Journal of Gastroenterology

AIM To evaluate the relation between 12 polymorphisms and the development of gastric cancer (GC) and colorectal cancer (CRC). METHODS In this study, we included 125 individuals with GC diagnosis, 66 individuals with CRC diagnosis and 475 cancer-free

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::050e8560d4dc0dd637b248d39674d644
https://doi.org/10.3748/wjg.v23.i48.8533

Immunohistochemical breast cancer profile of women in the Brazilian Amazonia

Autor: Danielle Feio da Costa, Ney Pc Santos, Williams Fernandes Barra, Mayara Ferreira Mota, Eliude Rodrigues do Nascimento, Juliana Passos Pereira, Tayssa Cl Vilhena, Amanda Raquel Gomes, Eliude R. Nascimento

Publikováno v: Journal of Clinical Oncology. 33:e12641-e12641

e12641 Background: Advances in studies on cancer genetics allowed the perception that breast cancer is a complex group of tumors, that beyond similar topography and histologies, are molecular and g...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6008fdd0496723c3dc59bbf3d2b8a600
https://doi.org/10.1200/jco.2015.33.15_suppl.e12641

Risk of infectious toxicity associated with polymorphism in GSTP1 in children with acute lymphoblastic leukemia in a population of Amazonia

Autor: Ney Pc Santos, Laudreisa da Costa Pantoja, Darlen cardoso de Almeida, André Salim Khayat, Alayde Vieira Wanderley, Fernando Augusto Rodrigues Mello Jr

Publikováno v: Journal of Clinical Oncology. 32:e21006-e21006

e21006 Background: Acute Lymphoblastic Leukemia (ALL) is the main cancer affecting children and adolescents. In the North of Brazil, more specifically in the metropolitan region of Belem, the LLA r...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac88a04f252c16992bdf1a9ec5cc94bd
https://doi.org/10.1200/jco.2014.32.15_suppl.e21006

Dihydropyrimidine dehydrogenase gene (DPYD) polymorphisms associated with toxicity in patients treated with flourpyrimidines in northern Brazil

Autor: Samia Demachki, Williams Fernandes Barra, Andrea Kcr Santos, Mayara Ferreira Mota, Danielle Feio da Costa, Tayssa Cl Vilhena, Millene A Bechara, Ney Pc Santos, Paulo Pimentel Assumpção, Sidney Santos

Publikováno v: Journal of Clinical Oncology. 32:e13546-e13546

e13546 Background: DPD deficiency is associated with severe toxicity after 5-FU treatment. There are regional differences in tolerance to 5-FU. No data about toxicity to 5-FU in cancer patients in ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::211bb9099bbb09fa3018628895800c22
https://doi.org/10.1200/jco.2014.32.15_suppl.e13546