Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Next-generation RNA sequencing"'
Publikováno v:
International Journal of COPD, Vol Volume 19, Pp 363-374 (2024)
Jia Chen,1– 3 Xiaoyu Deng,1– 3 Hansheng Xie,1– 3 Caiyun Wang,1– 3 Jiefeng Huang,1– 3 Ningfang Lian1– 3 1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Fujian Medical University, Fuzhou, People’s R
Externí odkaz:
https://doaj.org/article/e44f52efc81f453082af44031248b1ae
Autor:
Tracy L. Stockley, Bryan Lo, Adrian Box, Andrea Gomez Corredor, John DeCoteau, Patrice Desmeules, Harriet Feilotter, Daria Grafodatskaya, Cynthia Hawkins, Weei Yuarn Huang, Iyare Izevbaye, Guylaine Lepine, Andreas I. Papadakis, Paul C. Park, Brandon S. Sheffield, Danh Tran-Thanh, Stephen Yip, Ming Sound Tsao
Publikováno v:
Current Oncology, Vol 30, Iss 4, Pp 3989-3997 (2023)
The detection of gene fusions by RNA-based next-generation sequencing (NGS) is an emerging method in clinical genetic laboratories for oncology biomarker testing to direct targeted therapy selections. A recent Canadian study (CANTRK study) comparing
Externí odkaz:
https://doaj.org/article/24b1f17f55c2433ebe284fadc6a7249a
Autor:
Ni Tien, Tien-Yuan Wu, Cheng-Li Lin, Fang-Yi Chu, Charles C. N. Wang, Chung Y. Hsu, Fuu-Jen Tsai, Yi-Jen Fang, Yun-Ping Lim
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionA potential association between epilepsy and subsequent type 2 diabetes mellitus (T2DM) has emerged in recent studies. However, the association between epilepsy, anti-epileptic drugs (AEDs), and the risk of T2DM development remains contro
Externí odkaz:
https://doaj.org/article/de312e5272da4d6cb044f24a16eb3ab5
Autor:
Tsai-Der Chuang, Nhu Ton, Shawn Rysling, Derek Quintanilla, Drake Boos, Jianjun Gao, Hayden McSwiggin, Wei Yan, Omid Khorram
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13441 (2023)
The objective of this study was to determine if the aberrant expression of select genes could form the basis for the racial disparity in fibroid characteristics. The next-generation RNA sequencing results were analyzed as fold change [leiomyomas/pair
Externí odkaz:
https://doaj.org/article/2cb16f5f36084f18865efbd2aed40028
Autor:
Qixia Shen, Lisha Teng, Yucheng Wang, Luying Guo, Feng Xu, Hongfeng Huang, Wenqing Xie, Qin Zhou, Ying Chen, Junwen Wang, Youying Mao, Jianghua Chen, Hong Jiang
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Focal segmental glomerulosclerosis (FSGS) has an over 30% risk of recurrence after kidney transplantation (Ktx) and is associated with an extremely high risk of graft loss. However, mechanisms remain largely unclear. Thus, this study identifies novel
Externí odkaz:
https://doaj.org/article/b968966104334287a4f773f25594c4b4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Tsai-Der Chuang, Jianjun Gao, Derek Quintanilla, Hayden McSwiggin, Drake Boos, Wei Yan, Omid Khorram
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3742 (2023)
Recent studies have demonstrated that somatic MED12 mutations in exon 2 occur at a frequency of up to 80% and have a functional role in leiomyoma pathogenesis. The objective of this study was to elucidate the expression profile of coding RNA transcri
Externí odkaz:
https://doaj.org/article/d1cd5918323340ccb6408a3157de513c
Autor:
Rong-mei Zhou, Ze-hui Shi, Kun Shan, Shu-jie Zhang, Yi-han Zhang, Yu Liang, Biao Yan, Chen Zhao
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Macrophage polarization is a process that macrophages exert different functions according to surrounding micro-environment. Macrophages commonly exist in two distinct subsets: classically activated M1 macrophages and alternatively activated M2 macrop
Externí odkaz:
https://doaj.org/article/86615df75fff4c2bbb5bdaf99675922d
Autor:
Xiaofeng Guo, Xiaoling Gao, Brendan T. Keenan, Jingxu Zhu, Dimitra Sarantopoulou, Jie Lian, Raymond J. Galante, Gregory R. Grant, Allan I. Pack
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-15 (2020)
Abstract Background Previous studies show that galanin neurons in ventrolateral preoptic nucleus (VLPO-Gal) are essential for sleep regulation. Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by comparing their trans
Externí odkaz:
https://doaj.org/article/b3e6c62eaf544906bcbe2262430d3045
Autor:
Maria L. Elkjaer, Tobias Frisch, Richard Reynolds, Tim Kacprowski, Mark Burton, Torben A. Kruse, Mads Thomassen, Jan Baumbach, Zsolt Illes
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract To identify pathogenetic markers and potential drivers of different lesion types in the white matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from 73 different WM areas. Compared to 25 WM controls, 6713 ou
Externí odkaz:
https://doaj.org/article/d6c83e801176419788562e1f9dd05599