Zobrazeno 1 - 10
of 1 415
pro vyhledávání: '"Newsholme P"'
Publikováno v:
Drug Design, Development and Therapy, Vol 2015, Iss default, Pp 5569-5578 (2015)
Kevin N Keane,1,2 Peter M Hinchliffe,2 Navid Namdar,2 Jason L Conceicao,2 Philip Newsholme,1 John L Yovich1,2 1School of Biomedical Sciences, Curtin Health Innovation Research Institute – Biosciences, Curtin University, 2PIVET Medical Centre, Perth
Externí odkaz:
https://doaj.org/article/e9b5a1a4c37846b08f126557f4a39958
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 36, Iss 2, Pp 153-163 (2003)
Glucose is widely accepted as the primary nutrient for the maintenance and promotion of cell function. This metabolite leads to production of ATP, NADPH and precursors for the synthesis of macromolecules such as nucleic acids and phospholipids. We pr
Externí odkaz:
https://doaj.org/article/209d08cfed114d7a9c0a810d2892a544
Autor:
Nneoma Okeke, Luke B. Snell, Balram Rathish, Amal Hussein, William Newsholme, Damien Mack, Aodhan Breathnach, Jonathan A. Otter
Publikováno v:
Infection Prevention in Practice, Vol 6, Iss 2, Pp 100325- (2024)
Summary: We investigated the dynamics of COVID-19 contacts subsequent conversion to SARS-CoV-2 infection in an inpatient setting across three National Health Service (NHS) Trusts. 9.2% (476/5,156) COVID-19 contacts met inclusion criteria, were typabl
Externí odkaz:
https://doaj.org/article/de71b8eda4ff4dec866fb67e577d669f
Autor:
Magdalon Juliana, Hatanaka Elaine, Romanatto Talita, Rodrigues Hosana G, Kuwabara Wilson MT, Scaife Caitriona, Newsholme Philip, Curi Rui
Publikováno v:
Lipids in Health and Disease, Vol 10, Iss 1, p 218 (2011)
Abstract Previous studies have demonstrated that long chain fatty acids influence fibroblast function at sub-lethal concentrations. This study is the first to assess the effects of oleic, linoleic or palmitic acids on protein expression of fibroblast
Externí odkaz:
https://doaj.org/article/860f34b099394b44a4bf46868934f1d8
Autor:
Philip Newsholme
Publikováno v:
Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-4 (2021)
Abstract Various nutrients can change cell structure, cellular metabolism, and cell function which is particularly important for cells of the immune system as nutrient availability is associated with the activation and function of diverse immune subs
Externí odkaz:
https://doaj.org/article/223267103f3c47758d3df8cabfd4b288
Akademický článek
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Akademický článek
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Autor:
Amy Woodfield, Tatiana Gonzales, Erik Helmerhorst, Simon Laws, Philip Newsholme, Tenielle Porter, Giuseppe Verdile
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15811 (2022)
Alzheimer’s disease (AD) and type 2 diabetes (T2D) are chronic diseases that share several pathological mechanisms, including insulin resistance and impaired insulin signalling. Their shared features have prompted the evaluation of the drugs used t
Externí odkaz:
https://doaj.org/article/db751b3aa8294e01be30d40c9ada386b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 15506 (2022)
In animal studies, HDAC inhibitors such as butyrate have been reported to reduce plasma cholesterol, while conferring protection from diabetes, but studies on the underlying mechanisms are lacking. This study compares the influence of butyrate and ot
Externí odkaz:
https://doaj.org/article/cdb0e71620f94650a5bfc0f277952e22
Autor:
Allifia Abbas, Charlotte Zheng, Claire van Nispen tot Pannerden, William Newsholme, Rachel Hilton
Publikováno v:
Clinical Infection in Practice, Vol 7, Iss , Pp 100021- (2020)
Background: Acute toxoplasmosis in the transplant recipient can be a serious infection and usually represents reactivation of latent infection. Primary toxoplasmosis after transplantation is much rarer and is associated with greater morbidity and mor
Externí odkaz:
https://doaj.org/article/5a362acc5ba04d14b4e5260eac5f860f