Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Newby, Jay"'
Autor:
MacLaurin, James, Newby, Jay M.
A collection of identical and independent rare event first passage times is considered. The problem of finding the fastest out of $N$ such events to occur is called an extreme first passage time. The rare event times are singular and limit to infinit
Externí odkaz:
http://arxiv.org/abs/2309.01827
Autor:
Ling, Yun, Lysy, Martin, Seim, Ian, Newby, Jay M., Hill, David B., Cribb, Jeremy, Forest, M. Gregory
In diverse biological applications, particle tracking of passive microscopic species has become the experimental measurement of choice -- when either the materials are of limited volume, or so soft as to deform uncontrollably when manipulated by trad
Externí odkaz:
http://arxiv.org/abs/1911.06451
Publikováno v:
Phys. Rev. E 100, 022408 (2019)
Single kinesin molecular motors can processively move along a microtubule (MT) a few micrometers on average before dissociating. However, cellular length scales over which transport occurs are several hundred microns and more. Why seemingly unreliabl
Externí odkaz:
http://arxiv.org/abs/1902.09672
Autor:
Seim, Ian, Cribb, Jeremy A., Newby, Jay M., Vasquez, Paula, Lysy, Martin, Forest, M. Gregory, Hill, David B.
We report observations of a remarkable scaling behavior with respect to concentration in the passive microbead rheology of two highly entangled polymeric solutions, polyethylene oxide (PEO) and hyaluronic acid (HA). This behavior was reported previou
Externí odkaz:
http://arxiv.org/abs/1810.06649
Particle tracking is a powerful biophysical tool that requires conversion of large video files into position time series, i.e. traces of the species of interest for data analysis. Current tracking methods, based on a limited set of input parameters t
Externí odkaz:
http://arxiv.org/abs/1704.03009
Publikováno v:
Phys. Rev. E 94, 042414 (2016)
The diffusion of a reactant to a binding target plays a key role in many biological processes. The reaction-radius at which the reactant and target may interact is often a small parameter relative to the diameter of the domain in which the reactant d
Externí odkaz:
http://arxiv.org/abs/1605.01279
Autor:
Newby, Jay, Allard, Jun
Publikováno v:
Phys. Rev. Lett. 116, 128101 (2016)
Certain biological reactions, such as receptor-ligand binding at cell-cell interfaces and macromolecules binding to biopolymers, require many smaller molecules crowding a reaction site to be cleared. Examples include the T cell interface, a key playe
Externí odkaz:
http://arxiv.org/abs/1603.01846
Autor:
Schwemmer, Michael A., Newby, Jay M.
Additive noise is known to produce counter-intuitive behaviors in nonlinear dynamical systems. Previously, it was shown that systems with a deterministic limit cycle can display bistable switching between metastable states in the presence of asymmetr
Externí odkaz:
http://arxiv.org/abs/1501.05688
Autor:
Newby, Jay
A general class of stochastic gene expression models with self regulation is considered. One or more genes randomly switch between regulatory states, each having a different mRNA transcription rate. The gene or genes are self regulating when the prot
Externí odkaz:
http://arxiv.org/abs/1412.8446
Autor:
Newby, Jay
A simple stochastic model of a self regulating gene that displays bistable switching is analyzed. While on, a gene transcribes mRNA at a constant rate. Transcription factors can bind to the DNA and affect the gene's transcription rate. Before an mRNA
Externí odkaz:
http://arxiv.org/abs/1407.4344