Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nevine A. Shalaby"'
Autor:
Nevine A. Shalaby, Raheel Sayed, Qiao Zhang, Shane Scoggin, Susan Eliazer, Adrian Rothenfluh, Michael Buszczak
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Jumonji (JmjC) domain proteins influence gene expression and chromatin organization by way of histone demethylation, which provides a means to regulate the activity of genes across the genome. JmjC proteins have been associated with many hum
Externí odkaz:
https://doaj.org/article/47ad0110818946e8ae66ce69c73acfe1
Autor:
Aylin R. Rodan, Addison R. Reed, Jorge H. Pinzon, Adrian Rothenfluh, Michael Buszczak, Nevine A. Shalaby
Publikováno v:
Alcoholism: Clinical and Experimental Research. 41:2015-2024
Background Long-lasting transcriptional changes underlie a number of adaptations that contribute to alcohol use disorders (AUD). Chromatin remodeling, including histone methylation, can confer distinct, long-lasting transcriptional changes, and histo
Autor:
Susan Eliazer, Qiao Zhang, Michael Buszczak, Raheel Sayed, Nevine A. Shalaby, Adrian Rothenfluh, Shane Scoggin
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Jumonji (JmjC) domain proteins influence gene expression and chromatin organization by way of histone demethylation, which provides a means to regulate the activity of genes across the genome. JmjC proteins have been associated with many human diseas
Autor:
Adrian Rothenfluh, Jorge H. Pinzon, Anjana S. Narayanan, Michael Buszczak, Rachel J. Dove, Aylin R. Rodan, Heike Wolfenberg, Nevine A. Shalaby, Morgan P. Ritz, Eugene Jennifer Jin
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reports
Scientific Reports
Jumonji (JmjC) domain proteins are known regulators of gene expression and chromatin organization by way of histone demethylation. Chromatin modification and remodeling provides a means to modulate the activity of large numbers of genes, but the impo
Publikováno v:
Science. 343:298-301
Germline Pol I RNA polymerase I (Pol I)–directed ribosomal RNA (rRNA) transcription has been extensively studied in mammalian cell lines and yeast. However, the functional significance of cell-specific regulation of Pol I transcription within devel
Autor:
Nevine A, Shalaby, Michael, Buszczak
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1463
The Drosophila ovary represents a key in vivo model used to study germline stem cell (GSC) maintenance and stem cell daughter differentiation because these cells and their somatic cell neighbors can be identified at single-cell resolution within thei
Autor:
Nevine A. Shalaby, Michael Buszczak
Publikováno v:
Methods in Molecular Biology ISBN: 9781493940158
The Drosophila ovary represents a key in vivo model used to study germline stem cell (GSC) maintenance and stem cell daughter differentiation because these cells and their somatic cell neighbors can be identified at single-cell resolution within thei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68db40cf33392d9e7b4a05a36b167cef
https://doi.org/10.1007/978-1-4939-4017-2_6
https://doi.org/10.1007/978-1-4939-4017-2_6
Autor:
George D. Tsibidis, Aikaterini Daskalaki, Kristina Kux, Marc A. T. Muskavitch, Giorgos Tsoumpekos, Nevine A. Shalaby, Christos Delidakis
Publikováno v:
The Journal of Cell Biology
Ubiquitylation of the intracellular domain of Drosophila Delta is necessary for Notch activation.
DSL proteins are transmembrane ligands of the Notch receptor. They associate with a RING (really interesting new gene) family E3 ubiquitin ligase,
DSL proteins are transmembrane ligands of the Notch receptor. They associate with a RING (really interesting new gene) family E3 ubiquitin ligase,
Autor:
Eric L. Pierce, Kristen M. Pfau, Marisa C. Osswalt, Annette L. Parks, Nevine A. Shalaby, Marc A. T. Muskavitch, Eric J. Morreale
Publikováno v:
Genetics. 182:1061-1076
Notch signaling is an evolutionarily conserved pathway essential for many cell fate specification events during metazoan development. We conducted a large-scale transposon-based screen in the developing Drosophila eye to identify genes involved in No
Autor:
Michael Buszczak, Nevine A. Shalaby, Shane Scoggin, P. Robin Hiesinger, Nathan D. Williams, Arnaldo Carreira-Rosario
Publikováno v:
Journal of Visualized Experiments.
The continued development of techniques for fast, large-scale manipulation of endogenous gene loci will broaden the use of Drosophila melanogaster as a genetic model organism for human-disease related research. Recent years have seen technical advanc