Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nevin J. Varghese"'
Autor:
Heather L. Teague, PhD, Nevin J. Varghese, BS, Lam C. Tsoi, PhD, Amit K. Dey, MD, Michael S. Garshick, MD, Joanna I. Silverman, BA, Yvonne Baumer, PhD, Charlotte L. Harrington, BA, Erin Stempinski, MS, Youssef A. Elnabawi, BS, Pradeep K. Dagur, PhD, Kairong Cui, PhD, Ilker Tunc, PhD, Fayaz Seifuddin, MSc, Aditya A. Joshi, MD, Elena Stansky, BS, Monica M. Purmalek, BS, Justin A. Rodante, PA, Andrew Keel, DNP, Tarek Z. Aridi, BS, Carmelo Carmona-Rivera, PhD, Gregory E. Sanda, BS, Marcus Y. Chen, MD, Mehdi Pirooznia, MD, PhD, J. Philip McCoy, Jr., PhD, Joel M. Gelfand, MD, Keji Zhao, PhD, Johann E. Gudjonsson, MD, PhD, Martin P. Playford, PhD, Mariana J. Kaplan, MD, Jeffrey S. Berger, MD, Nehal N. Mehta, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 1-14 (2019)
Summary: Psoriasis is an inflammatory skin disease associated with increased cardiovascular risk and serves as a reliable model to study inflammatory atherogenesis. Because neutrophils are implicated in atherosclerosis development, this study reports
Externí odkaz:
https://doaj.org/article/58c2052d89974c20b205441c9749fd1d
Autor:
Tarek Z Aridi, Ilker Tunc, Lam C. Tsoi, Elena Stansky, Mehdi Pirooznia, Joanna I Silverman, Marcus Y. Chen, Aditya A. Joshi, Kairong Cui, J. Philip McCoy, Joel M. Gelfand, Erin Stempinski, Charlotte L. Harrington, Martin P. Playford, Heather L. Teague, Andrew Keel, Nehal N. Mehta, Keji Zhao, Pradeep K. Dagur, Carmelo Carmona-Rivera, Justin A. Rodante, Gregory E. Sanda, Nevin J. Varghese, Johann E. Gudjonsson, Youssef A. Elnabawi, Jeffrey S. Berger, Michael S. Garshick, Mariana J. Kaplan, Amit K. Dey, Monica M. Purmalek, Yvonne Baumer, Fayaz Seifuddin
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 1-14 (2019)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • LDGs are a subset of neutrophils that were elevated in psoriasis and associated with the severity of disease. • In psoriasis, LDGs associated with noncalcified coronary plaque burden beyond cardiovascular risk fa
Highlights • LDGs are a subset of neutrophils that were elevated in psoriasis and associated with the severity of disease. • In psoriasis, LDGs associated with noncalcified coronary plaque burden beyond cardiovascular risk fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157c2c738446965567589637778fd200
https://doi.org/10.1016/j.jacbts.2018.10.008
https://doi.org/10.1016/j.jacbts.2018.10.008
Autor:
Youssef A. Elnabawi, Nevin J. Varghese, Harry Choi, Alexander V. Sorokin, Noor Khalil, Justin A. Rodante, Aarthi S Reddy, Yvonne Baumer, Joshua P Rivers, Jacob Groenendyk, Sotirios K. Karathanasis, Ruchi Gupta, Jenis Ortiz, Ranjitha Gaddipati, Mohammad Tarek Kabbany, Alan T. Remaley, Martin P. Playford, Heather L. Teague, David A. Bluemke, Andrew Keel, Agastya D Belur, Milena Aksentijevich, Charlotte L. Harrington, Leonard Genovese, Jonathan H. Chung, Mariana J. Kaplan, Amit K. Dey, Aditya A. Joshi, Emily L. Ongstad, Sundus S. Lateef, Aditya Goyal, Joseph B Lerman, Aparna A Sajja, Joel M. Gelfand, Marcus Y. Chen, Nehal N. Mehta
Publikováno v:
JAMA Dermatol
IMPORTANCE: Psoriasis, a chronic inflammatory skin disease associated with accelerated noncalcified coronary burden (NCB) by coronary computed tomography angiography (CCTA), accelerates lipoprotein oxidation in the form of oxidized modified lipoprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6bc09d8f74ccf9b33017fa9a702d0a
https://pubmed.ncbi.nlm.nih.gov/31746956
https://pubmed.ncbi.nlm.nih.gov/31746956
Autor:
Pradeep K. Dagur, Aditya Goyal, Martin P. Playford, Amit K. Dey, Elena Stansky, Nehal N. Mehta, Heather L. Teague, Milena Aksentijevich, Marcus Y. Chen, Youssef A. Elnabawi, J. Philip McCoy, Nevin J. Varghese, Christopher S. Hourigan, Joanna I Silverman, Joel M. Gelfand
Publikováno v:
J Invest Dermatol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15845fef1cbca9295ff8828a8b5aba8e
https://pubmed.ncbi.nlm.nih.gov/31539534
https://pubmed.ncbi.nlm.nih.gov/31539534
Autor:
Nevin J. Varghese, Syevda Sirenko, Dongmei Yang, Tatiana M. Vinogradova, Kirill V. Tarasov, Alexey E. Lyashkov, Khalid Chakir, Edward G. Lakatta, Yue Li, Bruce D. Ziman, Yevgeniya O. Lukyanenko
Publikováno v:
Circulation: Arrhythmia and Electrophysiology. 11
Background: Spontaneous firing of sinoatrial node cells (SANCs) is regulated by cAMP-mediated, PKA (protein kinase A)-dependent (cAMP/PKA) local subsarcolemmal Ca 2+ releases (LCRs) from RyRs (ryanodine receptors). LCRs occur during diastolic depolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c2129912353c596dd5a3ce028be8f8
https://doi.org/10.1161/circep.117.005896
https://doi.org/10.1161/circep.117.005896
Autor:
Justin A. Rodante, Alexander V. Sorokin, Heather L. Teague, Gregory E. Sanda, Nevin J. Varghese, Christopher K. E. Bleck, Amit K. Dey, Howard S. Kruth, Charlotte L. Harrington, Pradeep K. Dagur, Yvonne Baumer, Aditya A. Joshi, Nehal N. Mehta, Martin P. Playford, Qimin Ng
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38
Objective: Atherogenesis is an inflammatory process accelerated in psoriasis, a chronic inflammatory skin disease associated with premature cardiovascular diseases (CVD). Cholesterol crystal (CC) formation is implicated at onset and progression of at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f918c2c39fcfb6ec54709646772f121
https://doi.org/10.1161/atvb.38.suppl_1.212
https://doi.org/10.1161/atvb.38.suppl_1.212
Autor:
Charlotte L. Harrington, M. Peter Marinkovich, Heather L. Teague, Zu-Xi Yu, Qimin Ng, Pradeep K. Dagur, Justin A. Rodante, Gregory E. Sanda, Alexander V. Sorokin, Howard S. Kruth, Martin P. Playford, Joanna I Silverman, Mårten C.G. Winge, Aditya A. Joshi, Nevin J. Varghese, Amit K. Dey, Agastya D Belur, Joel M. Gelfand, Nehal N. Mehta, Crystal L. Thomas, Yvonne Baumer, Aditya Goyal, Christopher K. E. Bleck, Shawn Rose, Danielle A. Springer
Publikováno v:
JCI insight. 3(1)
Inflammation is critical to atherogenesis. Psoriasis is a chronic inflammatory skin disease that accelerates atherosclerosis in humans and provides a compelling model to understand potential pathways linking these diseases. A murine model capturing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e742027de3bcd42f5cb67bd0a22cc347
https://pubmed.ncbi.nlm.nih.gov/29321372
https://pubmed.ncbi.nlm.nih.gov/29321372
Autor:
Leonard Genovese, Parag Shukla, Mark A. Ahlman, Agastya D Belur, Youssef A. Elnabawi, Heather L. Teague, Nehal N. Mehta, Nevin J. Varghese, Martin P. Playford, Yvonne Baumer, Jacob Groenendyk, Jonathan H. Chung, Aditya Goyal, Aparna Sajja, Charlotte L. Harrington, Joshua P Rivers, Tushina Jain, Aditya A. Joshi, Amit K. Dey, Justin A. Rodante, Joel Gelfand, Alan T. Remaley
Publikováno v:
Journal of the American College of Cardiology. 71:A1688
Psoriasis (PSO), a chronic inflammatory disease associated with dysfunctional lipoprotein profile and increased vascular inflammation (VI) by 18-FDG PET/CT, provides a reliable human model to study the effect of lipoprotein modulation on progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79f561c847ca3a933ae291dc77c96344
https://doi.org/10.1016/s0735-1097(18)32229-0
https://doi.org/10.1016/s0735-1097(18)32229-0