Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Nevin, Celebi"'
Publikováno v:
Pharmaceutical Development and Technology. 27:1027-1037
The objective of this study was to develop ritonavir (RTV) nanosuspensions (NSs) by microfluidization method. Particle size (PS) measurements were performed by photon correlation spectroscopy. Amorphous properties of the particles were evaluated by X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ca7ed0fd540d5cbd3fb4922341bdcc
https://doi.org/10.1080/10837450.2022.2145309
https://doi.org/10.1080/10837450.2022.2145309
Publikováno v:
Pharmaceutical Research. 38:991-1009
Purpose The objective of this study was to optimize the Flurbiprofen (FB) nanosuspension (NS) based gel and to investigate the in vitro release, ex vivo permeation, the plasma concentration-time profile and pharmacokinetic parameters. Methods FB-NSs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eddff55a204e897240ed5217b5754005
https://doi.org/10.1007/s11095-021-03060-6
https://doi.org/10.1007/s11095-021-03060-6
Publikováno v:
Turkish Journal of Pharmaceutical Sciences. 18:223-227
Objectives The current study focused on the evaluation of the cytotoxic effect and permeability of ziprasidone hydrochloride monohydrate (ZHM) nanocrystals on Caco-2 cells. Materials and methods ZHM nanocrystals were prepared by the microfluidization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9058c909803b263aacef41d24ef9cbc5
https://doi.org/10.4274/tjps.galenos.2020.67366
https://doi.org/10.4274/tjps.galenos.2020.67366
Publikováno v:
Journal of Drug Delivery Science and Technology. 79:104012
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fa99a7339f30680035071599d31e36
https://doi.org/10.1016/j.jddst.2022.104012
https://doi.org/10.1016/j.jddst.2022.104012
Publikováno v:
Journal of microencapsulation. 38(4)
The objective of this study was to develop dermal nanosuspension (NS) based gel formulation of etodolac (ETD).Etodolac nanosuspension (ETD-NS) was prepared by wet milling method and dispersed in hydroxypropyl methylcellulose (NS-HPMC) or hydroxyethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97acab04b3647df18cebf4dff38ac0b8
https://pubmed.ncbi.nlm.nih.gov/33752553
https://pubmed.ncbi.nlm.nih.gov/33752553
The objective of this study was to prepare a stable self-nanoemulsifying formulation of exendin-4, which is an antidiabetic peptide. As exendin-4 is commercially available only in subcutaneous form, several attempts have been made to discover an effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8384f14f96d241a6106a1c6727d2bfaf
https://avesis.erciyes.edu.tr/publication/details/e8149cfa-9ec8-411c-b1b3-6cbc9b589b1f/oai
https://avesis.erciyes.edu.tr/publication/details/e8149cfa-9ec8-411c-b1b3-6cbc9b589b1f/oai
Flurbiprofen (FB) is an analgesic and anti-inflammatory drug, but its low water solubility (BCS Class II) limits its dermal bioavailability. The aim of this study is to develop a FB nanosuspension (NS) based gel and to evaluate its analgesic and anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0988670dd28cf578f2f1be876cfa7b10
https://avesis.gazi.edu.tr/publication/details/144af911-1e01-4270-97c3-0f14553fd667/oai
https://avesis.gazi.edu.tr/publication/details/144af911-1e01-4270-97c3-0f14553fd667/oai
Publikováno v:
Amino acids. 53(1)
The objective of this study was to prepare a stable self-nanoemulsifying formulation of exendin-4, which is an antidiabetic peptide. As exendin-4 is commercially available only in subcutaneous form, several attempts have been made to discover an effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::38fff3ffc4cf6943eff70c5c8957ed77
https://pubmed.ncbi.nlm.nih.gov/33398527
https://pubmed.ncbi.nlm.nih.gov/33398527
Although flurbiprofen (FB), as one of non-steroidal anti-inflammatory drugs, has various pharmacological applications, it shows low dermal bioavailability due to its low water solubility. To overcome this solubility problem, FB nanosuspensions were d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8219f178b388e0347b2bac7bcc5f69cd
https://avesis.gazi.edu.tr/publication/details/f7bdfb2b-1c81-4c19-895f-481189e23af5/oai
https://avesis.gazi.edu.tr/publication/details/f7bdfb2b-1c81-4c19-895f-481189e23af5/oai
Autor:
Alptug Karakucuk, Nevin Celebi
Publikováno v:
Pharmaceutical Research. 37
Purpose Etodolac (ETD) is one of the non-steroidal anti-inflammatory drugs which has low aqueous solubility issues. The objective of this study was to develop ETD nanosuspensions to improve its poor aqueous solubility properties while investigating f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b2bcb6dfdaf1d6b0b146f3c75c931d9
https://doi.org/10.1007/s11095-020-02815-x
https://doi.org/10.1007/s11095-020-02815-x