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of 262
pro vyhledávání: '"Neville N. Osborne"'
Autor:
Simone Beretta, John P.M. Wood, Barry Derham, Gessica Sala, Lucio Tremolizzo, Carlo Ferrarese, Neville N. Osborne
Publikováno v:
Neurobiology of Disease, Vol 24, Iss 2, Pp 308-317 (2006)
Leber Hereditary Optic Neuropathy (LHON) is a maternally inherited form of visual loss, due to selective degeneration of retinal ganglion cells. Despite the established aetiological association between LHON and mitochondrial DNA mutations affecting c
Externí odkaz:
https://doaj.org/article/f394c48bf4c24d46b90cba8281543469
Autor:
Susana del Olmo-Aguado, Claudia Núñez-Álvarez, Andrés Fernández-Vega, Neville N. Osborne, Amador Menéndez-Velázquez, Jesus Merayo-Lloves
Publikováno v:
Optical Materials. 86:505-511
The use of filters in ophthalmology is not new, but usually they operate by just blocking light of a particular wavelength. In contrast, photoluminescence filters are theoretically able to provide an altered wavelength of light to reach the retina, a
Publikováno v:
Experimental Eye Research. 161:106-115
In the present study mechanical damage to the corneal endothelium was induced by elevation of intraocular pressure (IOP, 140 mmHg, 60 min) to one eye of rats, delivered either in complete darkness or in the presence of red light (16.5 W/m 2 , 3000 lx
Publikováno v:
European Journal of Pharmacology. 787:127-133
Primary open-angle glaucoma (POAG) is a common form of glaucoma in which retinal ganglion cells (RGCs) die at varying intervals. Primary open-angle glaucoma is often associated with an increased intraocular pressure (IOP), which when reduced, can slo
Publikováno v:
Experimental eye research. 180
The aim of the present study was to analyse how short wave blue and long wave red light differentially affect corneal epithelial (HCE-2) cells in culture. The corneal epithelium in situ is exposed to more blue light than in the past because of Light
Publikováno v:
Acta ophthalmologica. 97(1)
Purpose To ascertain whether red light, known to enhance mitochondrial function, can blunt a blue light insult to ARPE19 cells in culture. Methods Semi-confluent ARPE19 cells cultured in 10% FBS were subjected to various regimes of treatment with blu
Autor:
Neville N. Osborne, Lorne A. Whitehead
Publikováno v:
PROCEEDINGS OF THE CONFERENCE AT THE CIE MIDTERM MEETING 2017 23 – 25 OCTOBER 2017, JEJU, REPUBLIC OF KOREA.
Publikováno v:
Experimental Eye Research. 128:8-14
The retina is the only part of the central nervous system that is exposed to light radiation between 400 and 780 nm. Short wavelength light (SWL) ranging between 400 and 480 nm are absorbed maximally by chromophores located in mitochondria. An abunda
Publikováno v:
Drug Discovery Today. 19:1613-1622
Neurons depend on their mitochondria for optimum function and become susceptible with age. Mitochondrial function is gradually impaired during aging because more electrons are converted to reactive oxygen species rather than being converted to ATP. R
Publikováno v:
Metallomics. 6:274-278
Proton-induced X-ray emission (PIXE) in combination with 3D depth profiling with Rutherford backscattering spectrometry (RBS) was used to establish the distribution and concentration of trace elements within individual corneal and retinal areas in fr