Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Neville Mdc"'
Autor:
Ayesha Noorani, Coorens Thh, Oliver Trw, Thomas J. Mitchell, Michael R. Stratton, Raheleh Rahbari, James Hewinson, Peter J. Campbell, Alex Cagan, Luiza Moore, Christopher J, Rashesh Sanghvi, Rebecca C. Fitzgerald, Neville Mdc, Philip S. Robinson, Inigo Martincorena, Yvette Hooks
Starting from the zygote, all cells in the developing and adult human body continuously acquire mutations. A mutation shared between two different cells implies a shared progenitor cell and can thus be used as a naturally occurring marker for lineage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6556a56a671440b18c411a8da2b715b
https://doi.org/10.1101/2020.11.25.397828
https://doi.org/10.1101/2020.11.25.397828
Autor:
Oliver TRW; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Chappell L; Wellcome Sanger Institute, Hinxton, UK., Sanghvi R; Wellcome Sanger Institute, Hinxton, UK., Deighton L; Wellcome Sanger Institute, Hinxton, UK., Ansari-Pour N; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Dentro SC; Wellcome Sanger Institute, Hinxton, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Young MD; Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Wellcome Sanger Institute, Hinxton, UK., Jung H; Wellcome Sanger Institute, Hinxton, UK., Butler T; Wellcome Sanger Institute, Hinxton, UK., Neville MDC; Wellcome Sanger Institute, Hinxton, UK., Leongamornlert D; Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands., Hooks Y; Wellcome Sanger Institute, Hinxton, UK., Cagan A; Wellcome Sanger Institute, Hinxton, UK., Mitchell TJ; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Cortes-Ciriano I; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Cambridge, UK., Warren AY; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Wedge DC; Big Data Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Manchester Cancer Research Centre, Division of Cancer Sciences, University of Manchester, Manchester, UK., Heer R; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle Urology, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Coleman N; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Murray MJ; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK., Rahbari R; Wellcome Sanger Institute, Hinxton, UK. rr11@sanger.ac.uk., Behjati S; Wellcome Sanger Institute, Hinxton, UK. sb31@sanger.ac.uk.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK. sb31@sanger.ac.uk.; Department of Paediatrics, University of Cambridge, Cambridge, UK. sb31@sanger.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2022 Aug 11; Vol. 13 (1), pp. 4272. Date of Electronic Publication: 2022 Aug 11.
Autor:
Gardner EJ; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, Hinxton, UK.; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Neville MDC; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, Hinxton, UK., Samocha KE; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, Hinxton, UK., Barclay K; Max Planck Institute for Demographic Research, Rostock, Germany.; Demography Unit, Department of Sociology, Stockholm University, Stockholm, Sweden.; Swedish Collegium for Advanced Study, Uppsala, Sweden., Kolk M; Demography Unit, Department of Sociology, Stockholm University, Stockholm, Sweden., Niemi MEK; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, Hinxton, UK., Kirov G; Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK., Martin HC; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, Hinxton, UK., Hurles ME; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, Hinxton, UK. meh@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2022 Mar; Vol. 603 (7903), pp. 858-863. Date of Electronic Publication: 2022 Mar 23.
Autor:
Moore L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Cagan A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Coorens THH; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Neville MDC; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Sanghvi R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Sanders MA; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Hematology, Erasmus University Medical Center, Rotterdam, Netherlands., Oliver TRW; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Leongamornlert D; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Ellis P; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Inivata, Cambridge, UK., Noorani A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Mitchell TJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Butler TM; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Hooks Y; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Warren AY; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Jorgensen M; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK., Dawson KJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Menzies A; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., O'Neill L; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Latimer C; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Teng M; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., van Boxtel R; Princess Máxima Center for Pediatric Oncology and Oncode Institute, Utrecht, Netherlands., Iacobuzio-Donahue CA; Department of Pathology, Sol Goldman Pancreatic Cancer Research Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Martincorena I; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Heer R; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Newcastle Urology, Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Campbell PJ; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK., Fitzgerald RC; MRC Cancer Unit, University of Cambridge, Cambridge, UK., Stratton MR; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK. mrs@sanger.ac.uk., Rahbari R; Cancer, Ageing and Somatic Mutation (CASM), Wellcome Sanger Institute, Hinxton, UK. rr11@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2021 Sep; Vol. 597 (7876), pp. 381-386. Date of Electronic Publication: 2021 Aug 25.
Autor:
Coorens THH; Wellcome Sanger Institute, Hinxton, UK., Moore L; Wellcome Sanger Institute, Hinxton, UK.; Department of Pathology, University of Cambridge, Cambridge, UK., Robinson PS; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK., Sanghvi R; Wellcome Sanger Institute, Hinxton, UK., Christopher J; Wellcome Sanger Institute, Hinxton, UK.; Department of Paediatrics, University of Cambridge, Cambridge, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hewinson J; Wellcome Sanger Institute, Hinxton, UK., Przybilla MJ; Wellcome Sanger Institute, Hinxton, UK., Lawson ARJ; Wellcome Sanger Institute, Hinxton, UK., Spencer Chapman M; Wellcome Sanger Institute, Hinxton, UK.; Department of Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Cagan A; Wellcome Sanger Institute, Hinxton, UK., Oliver TRW; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Neville MDC; Wellcome Sanger Institute, Hinxton, UK., Hooks Y; Wellcome Sanger Institute, Hinxton, UK., Noorani A; Wellcome Sanger Institute, Hinxton, UK., Mitchell TJ; Wellcome Sanger Institute, Hinxton, UK.; Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Department of Surgery, University of Cambridge, Cambridge, UK., Fitzgerald RC; MRC Cancer Unit, University of Cambridge, Biomedical Campus, Cambridge, UK., Campbell PJ; Wellcome Sanger Institute, Hinxton, UK., Martincorena I; Wellcome Sanger Institute, Hinxton, UK., Rahbari R; Wellcome Sanger Institute, Hinxton, UK., Stratton MR; Wellcome Sanger Institute, Hinxton, UK. mrs@sanger.ac.uk.
Publikováno v:
Nature [Nature] 2021 Sep; Vol. 597 (7876), pp. 387-392. Date of Electronic Publication: 2021 Aug 25.
Autor:
Neville MDC; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom., Kohze R; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom., Erady C; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom., Meena N; Department of Biology, Indian Institute of Science Education and Research, Pune, Maharashtra 411008, India., Hayden M; Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff CF14 4XN, United Kingdom., Cooper DN; Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff CF14 4XN, United Kingdom., Mort M; Institute of Medical Genetics, Cardiff University, Heath Park, Cardiff CF14 4XN, United Kingdom., Prabakaran S; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.; Department of Biology, Indian Institute of Science Education and Research, Pune, Maharashtra 411008, India.; St Edmund's College, University of Cambridge, Cambridge CB3 0BN, United Kingdom.
Publikováno v:
Genome research [Genome Res] 2021 Feb; Vol. 31 (2), pp. 327-336. Date of Electronic Publication: 2021 Jan 19.
Autor:
Martin HC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK. hcm@sanger.ac.uk., Gardner EJ; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Samocha KE; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Kaplanis J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Akawi N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Sifrim A; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Human Genetics, University of Leuven, Leuven, Belgium., Eberhardt RY; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Tavares ALT; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Clinical Genetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.; Genomics England, Queen Mary University of London, London, EC1M 6BQ, UK., Neville MDC; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK., Niemi MEK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Institute for Molecular Medicine Finland, University of Helsinki, Tukholmankatu 8, Helsinki, FI-00014, Finland., Gallone G; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Max Planck Institute for Molecular Genetics, Ihnestraße 63, 14195, Berlin, Germany., McRae J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Illumina Inc., 5200 Illumina Way, San Diego, CA, 92122, USA., Wright CF; Institute of Biomedical & Clinical Science, University of Exeter Medical School, Exeter, EX2 5DW, UK., FitzPatrick DR; MRC Human Genetics Unit, MRC IGMM, University of Edinburgh, Western General Hospital, Edinburgh, EH4 2XU, UK., Firth HV; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.; Department of Clinical Genetics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Hurles ME; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.
Publikováno v:
Nature communications [Nat Commun] 2021 Jan 27; Vol. 12 (1), pp. 627. Date of Electronic Publication: 2021 Jan 27.
Autor:
Neville MDC; Department of Biomedical and Molecular Sciences, Queen's University, Botterell Hall, Room 530 - 18 Stuart St, Kingston, ON, K7L3N6, Canada., Choi J; Department of Biomedical and Molecular Sciences, Queen's University, Botterell Hall, Room 530 - 18 Stuart St, Kingston, ON, K7L3N6, Canada., Lieberman J; Department of Biomedical and Molecular Sciences, Queen's University, Botterell Hall, Room 530 - 18 Stuart St, Kingston, ON, K7L3N6, Canada., Duan QL; Department of Biomedical and Molecular Sciences, Queen's University, Botterell Hall, Room 530 - 18 Stuart St, Kingston, ON, K7L3N6, Canada. qingling.duan@queensu.ca.; School of Computing, Queen's University, 557 Goodwin Hall, Room 531, Kingston, ON, K7L 2N8, Canada. qingling.duan@queensu.ca.
Publikováno v:
Respiratory research [Respir Res] 2018 Dec 12; Vol. 19 (1), pp. 248. Date of Electronic Publication: 2018 Dec 12.