Zobrazeno 1 - 10
of 761
pro vyhledávání: '"Neville K"'
Since its introduction to the public, ChatGPT has had an unprecedented impact. While some experts praised AI advancements and highlighted their potential risks, others have been critical about the accuracy and usefulness of Large Language Models (LLM
Externí odkaz:
http://arxiv.org/abs/2407.18607
Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying causal stru
Externí odkaz:
http://arxiv.org/abs/2406.09207
Autor:
Lawrence T Wang, Lais S Pereira, Patience K Kiyuka, Arne Schön, Neville K Kisalu, Rachel Vistein, Marlon Dillon, Brian G Bonilla, Alvaro Molina-Cruz, Carolina Barillas-Mury, Joshua Tan, Azza H Idris, Joseph R Francica, Robert A Seder
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010133 (2021)
Combinations of monoclonal antibodies (mAbs) against different epitopes on the same antigen synergistically neutralize many viruses. However, there are limited studies assessing whether combining human mAbs against distinct regions of the Plasmodium
Externí odkaz:
https://doaj.org/article/d385b3ce72a7496ba9242f6f5b20828b
Autor:
Yevel Flores-Garcia, Lawrence T. Wang, Minah Park, Beejan Asady, Azza H. Idris, Neville K. Kisalu, Christian Muñoz, Lais S. Pereira, Joseph R. Francica, Robert A. Seder, Fidel Zavala
Publikováno v:
PLoS Pathogens, Vol 17, Iss 11 (2021)
Rare and potent monoclonal antibodies (mAbs) against the Plasmodium falciparum (Pf) circumsporozoite protein (CSP) on infective sporozoites (SPZ) preferentially bind the PfCSP junctional tetrapeptide NPDP or NVDP minor repeats while cross-reacting wi
Externí odkaz:
https://doaj.org/article/111b6dad7a6b41a189095f7767ef2b17
Autor:
Neville K. Kisalu, Lais D. Pereira, Keenan Ernste, Yevel Flores-Garcia, Azza H. Idris, Mangaiarkarasi Asokan, Marlon Dillon, Scott MacDonald, Wei Shi, Xuejun Chen, Amarendra Pegu, Arne Schön, Fidel Zavala, Alejandro B. Balazs, Joseph R. Francica, Robert A. Seder
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
CIS43 is a potent neutralizing human mAb that targets a highly conserved “junctional” epitope in the Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP). Enhancing the durability of CIS43 in vivo will be important for clinical translation
Externí odkaz:
https://doaj.org/article/ec22f87b3a434413a25e71b29c3ef1c2
Causal Bayesian Networks (CBNs) are an important tool for reasoning under uncertainty in complex real-world systems. Determining the graphical structure of a CBN remains a key challenge and is undertaken either by eliciting it from humans, using mach
Externí odkaz:
http://arxiv.org/abs/2310.11154
Autor:
Constantinou, Anthony, Kitson, Neville K., Liu, Yang, Chobtham, Kiattikun, Hashemzadeh, Arian, Nanavati, Praharsh A., Mbuvha, Rendani, Petrungaro, Bruno
Causal machine learning (ML) algorithms recover graphical structures that tell us something about cause-and-effect relationships. The causal representation praovided by these algorithms enables transparency and explainability, which is necessary for
Externí odkaz:
http://arxiv.org/abs/2305.03859
Causal Bayesian Networks provide an important tool for reasoning under uncertainty with potential application to many complex causal systems. Structure learning algorithms that can tell us something about the causal structure of these systems are bec
Externí odkaz:
http://arxiv.org/abs/2206.08952
Autor:
Henri A Thomassen, Trevon Fuller, Salvi Asefi-Najafabady, Julia A G Shiplacoff, Prime M Mulembakani, Seth Blumberg, Sara C Johnston, Neville K Kisalu, Timothée L Kinkela, Joseph N Fair, Nathan D Wolfe, Robert L Shongo, Matthew LeBreton, Hermann Meyer, Linda L Wright, Jean-Jacques Muyembe, Wolfgang Buermann, Emile Okitolonda, Lisa E Hensley, James O Lloyd-Smith, Thomas B Smith, Anne W Rimoin
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66071 (2013)
Climate change is predicted to result in changes in the geographic ranges and local prevalence of infectious diseases, either through direct effects on the pathogen, or indirectly through range shifts in vector and reservoir species. To better unders
Externí odkaz:
https://doaj.org/article/0c2a90c1b6d94065881205f7333858d4
In Bayesian Networks (BNs), the direction of edges is crucial for causal reasoning and inference. However, Markov equivalence class considerations mean it is not always possible to establish edge orientations, which is why many BN structure learning
Externí odkaz:
http://arxiv.org/abs/2112.10574