Výsledky vyhledávání - "Neville C. Wathen"

Interferon-α drives T cell-mediated immunopathology in the intestine

Autor: Neville C. Wathen, Sylvia L.F. Pender, Giovanni Monteleone, Thomas T. MacDonald

Publikováno v: European Journal of Immunology. 31:2247-2255

The ability of interferon (IFN)-alpha to induce autoimmunity and exacerbate Th1 diseases is well known. We have recently described enhanced expression of IFN-alpha in the mucosa of patients with celiac disease (CD), a gluten-sensitive Th1-mediated en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f90a33e84ea9b539e32cbf6b9336b11
https://doi.org/10.1002/1521-4141(200108)31:8<2247::aid-immu2247>3.0.co

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Interactions between stromal cell--derived keratinocyte growth factor and epithelial transforming growth factor in immune-mediated crypt cell hyperplasia

Autor: Neville C. Wathen, Mona Bajaj-Elliott, Richard Poulsom, T T MacDonald, Sylvia L.F. Pender

Publikováno v: Journal of Clinical Investigation. 102:1473-1480

Immune reactions in the gut are associated with increased epithelial cell proliferation. Here we have studied the role of keratinocyte growth factor (KGF; FGF7) and transforming growth factor-alpha (TGF-alpha) in the epithelial cell hyperplasia seen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e786703e76b7c0b89d948fb176a4e4
https://doi.org/10.1172/jci2792

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