SDS-induced hexameric oligomerization of myotoxin-II from Bothrops asper assessed by sedimentation velocity and nuclear magnetic resonance.

Autor: Henrickson A; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB, Canada., Montina T; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB, Canada., Hazendonk P; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB, Canada., Lomonte B; Instituto Clodomiro Picado, Facultad de Microbiología San José, Universidad de Costa Rica, San José, Costa Rica., Neves-Ferreira AGC; Laboratory of Toxinology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil., Demeler B; Department of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB, Canada. demeler@gmail.com.; Department of Chemistry and Biochemistry, University of Montana, Missoula, MT, USA. demeler@gmail.com.

Publikováno v: European biophysics journal : EBJ [Eur Biophys J] 2023 Jul; Vol. 52 (4-5), pp. 445-457. Date of Electronic Publication: 2023 May 20.

Combination of E- and NS1-Derived DNA Vaccines: The Immune Response and Protection Elicited in Mice against DENV2.

Autor: Pinto PBA; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Barros TAC; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Lima LM; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Pacheco AR; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Assis ML; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Pereira BAS; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Gonçalves AJS; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Azevedo AS; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Neves-Ferreira AGC; Laboratory of Toxinology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Costa SM; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil., Alves AMB; Laboratory of Biotechnology and Physiology of Viral Infections, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-900, RJ, Brazil.

Publikováno v: Viruses [Viruses] 2022 Jun 30; Vol. 14 (7). Date of Electronic Publication: 2022 Jun 30.

The Interaction of the Antitoxin DM43 with a Snake Venom Metalloproteinase Analyzed by Mass Spectrometry and Surface Plasmon Resonance

Autor: Brand, GD, Salbo, R, Jorgensen, TJD, Jr, BC, Erba, EB, Robinson, CV, Tanjoni, I, Moura-da-Silva, AM, Roepstorff, P, Domont, GB, Perales, J, Valente, RH, Neves-Ferreira, AGC

Publikováno v: Brand, G D, Salbo, R, Jørgensen, T J D, Bloch, C, Boeri Erba, E, Robinson, S C, Tanjoni, I, Moura-da-Silva, A M, Roepstorff, P, Domont, G B, Perales, J, Valente, R H & Neves-Ferreira, A G C 2012, ' The interaction of the antitoxin DM43 with a snake venom metalloproteinase analyzed by mass spectrometry and surface plasmon resonance ', Journal of Mass Spectrometry, vol. 47, no. 5, pp. 567-73 . https://doi.org/10.1002/jms.2990

DM43 is a circulating dimeric antitoxin isolated from Didelphis aurita, a South American marsupial naturally immune to snake envenomation. This endogenous inhibitor binds non-covalently to jararhagin, the main hemorrhagic metalloproteinase from Bothr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::41a0c5e4280af9e2e7858713da7ef289
https://ora.ox.ac.uk/objects/uuid:f511d2ee-3a18-4acf-81c6-1097ba9fa83c

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study.

Autor: Iacobucci C; Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center , Martin Luther University Halle-Wittenberg , Kurt-Mothes-Strasse 3a , 06120 Halle/Saale , Germany., Piotrowski C; Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center , Martin Luther University Halle-Wittenberg , Kurt-Mothes-Strasse 3a , 06120 Halle/Saale , Germany., Aebersold R; Department of Biology, Institute of Molecular Systems Biology , ETH Zurich , Otto-Stern-Weg 3 , 8093 Zurich , Switzerland.; Faculty of Science , University of Zurich , 8006 Zurich , Switzerland., Amaral BC; Institute of Chemistry , University of Campinas , Campinas São Paulo 13083-970 , Brazil., Andrews P; Departments of Biological Chemistry, Bioinformatics, and Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States., Bernfur K; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science , Lund University , 221 00 Lund , Sweden., Borchers C; University of Victoria-Genome British Columbia Proteomics Centre , Vancouver Island Technology Park , Victoria , British Columbia V8Z 7X8 , Canada.; Department of Biochemistry and Microbiology , University of Victoria , Petch Building, Room 270d, 3800 Finnerty Road , Victoria , British Columbia V8P 5C2 , Canada.; Gerald Bronfman Department of Oncology, Jewish General Hospital , McGill University , 3755 Côte Ste-Catherine Road , Montréal , Quebec H3T 1E2 , Canada.; Proteomics Centre, Segal Cancer Centre, Lady Davis Institute, Jewish General Hospital , McGill University , 3755 Côte Ste-Catherine Road , Montréal , Quebec H3T 1E2 , Canada., Brodie NI; University of Victoria-Genome British Columbia Proteomics Centre , Vancouver Island Technology Park , Victoria , British Columbia V8Z 7X8 , Canada., Bruce JE; Department of Genome Sciences , University of Washington , Seattle , Washington 98195 , United States., Cao Y; National Institute of Biological Sciences , Beijing 7 Science Park Road, ZGC Life Science Park , 102206 Beijing , China., Chaignepain S; CBMN, UMR 5248, CNRS , Université de Bordeaux, INP Bordeaux , Pessac 33607 , France., Chavez JD; Department of Genome Sciences , University of Washington , Seattle , Washington 98195 , United States., Claverol S; Centre de Génomique Fonctionnelle, Plateforme Protéome , Université de Bordeaux , Bordeaux 33000 , France., Cox J; Computational Systems Biochemistry Research Group , Max-Planck-Institute of Biochemistry , Am Klopferspitz 18 , 82152 Martinsried , Germany., Davis T; Department of Biochemistry , University of Washington , Seattle , Washington 98195 , United States., Degliesposti G; MRC Laboratory of Molecular Biology , Cambridge Biomedical Campus , Francis Crick Avenue , Cambridge CB2 0QH , U.K., Dong MQ; National Institute of Biological Sciences , Beijing 7 Science Park Road, ZGC Life Science Park , 102206 Beijing , China., Edinger N; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, Safra Campus Givat Ram , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel., Emanuelsson C; Department of Biochemistry and Structural Biology, Center for Molecular Protein Science , Lund University , 221 00 Lund , Sweden., Gay M; Institute for Research in Biomedicine (IRB Barcelona) , The Barcelona Institute of Science and Technology (BIST) , Baldiri Reixac 10 , 08028 Barcelona , Spain., Götze M; Institute for Biochemistry and Biotechnology, Charles Tanford Protein Center , Martin Luther University Halle-Wittenberg , Kurt-Mothes-Strasse 3a , 06120 Halle/Saale , Germany., Gomes-Neto F; Laboratory of Toxinology , Oswaldo Cruz Institute , Fiocruz, Avenida Brasil 4365 (Moorish Castle) , Manguinhos, Rio de Janeiro , Rio de Janeiro 21040-900 , Brazil., Gozzo FC; Institute of Chemistry , University of Campinas , Campinas São Paulo 13083-970 , Brazil., Gutierrez C; Department of Physiology & Biophysics , University of California , Irvine , California 92697 , United States., Haupt C; Interdisciplinary Research Center HALOmem, Institute for Biochemistry and Biotechnology, Charles Tanford Protein Center , Martin Luther University Halle-Wittenberg , Kurt-Mothes-Strasse 3a , 06120 Halle/Saale , Germany., Heck AJR; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences , University of Utrecht and Netherlands Proteomics Centre , Padualaan 8 , 3584 CH Utrecht , The Netherlands., Herzog F; Gene Center Munich, Department of Biochemistry, Faculty of Chemistry and Pharmacy , Ludwig Maximilians University of Munich , Feodor-Lynen-Strasse 25 , 81377 Munich , Germany., Huang L; Department of Physiology & Biophysics , University of California , Irvine , California 92697 , United States., Hoopmann MR; Institute for Systems Biology , 401 Terry Avenue North , Seattle , Washington 98109 , United States., Kalisman N; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, Safra Campus Givat Ram , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel., Klykov O; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences , University of Utrecht and Netherlands Proteomics Centre , Padualaan 8 , 3584 CH Utrecht , The Netherlands., Kukačka Z; Institute of Microbiology , BIOCEV , Prumyslova 595 , 252 50 Vestec , Czech Republic., Liu F; Leibniz Institute of Molecular Pharmacology (FMP) , Robert-Rössle-Strasse 10 , 13125 Berlin , Germany., MacCoss MJ; Department of Genome Sciences , University of Washington , Seattle , Washington 98195 , United States., Mechtler K; Protein Chemistry Facility, Research Institute of Molecular Pathology (IMP) and Institute of Molecular Biotechnology (IMBA) , Vienna Biocenter (VBC) , Dr. Bohr-Gasse 3 , 1030 Vienna , Austria., Mesika R; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, Safra Campus Givat Ram , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel., Moritz RL; Institute for Systems Biology , 401 Terry Avenue North , Seattle , Washington 98109 , United States., Nagaraj N; Biochemistry Core Facility , Max-Planck-Institute of Biochemistry , Am Klopferspitz 18 , 82152 Martinsried , Germany., Nesati V; Analytical Biochemistry, CSL Limited , Bio21 Institute , 30 Flemington Road , 3010 Parkville, Melbourne , Australia., Neves-Ferreira AGC; Laboratory of Toxinology , Oswaldo Cruz Institute , Fiocruz, Avenida Brasil 4365 (Moorish Castle) , Manguinhos, Rio de Janeiro , Rio de Janeiro 21040-900 , Brazil., Ninnis R; Analytical Biochemistry, CSL Limited , Bio21 Institute , 30 Flemington Road , 3010 Parkville, Melbourne , Australia., Novák P; Institute of Microbiology , BIOCEV , Prumyslova 595 , 252 50 Vestec , Czech Republic., O'Reilly FJ; Chair of Bioanalytics, Institute of Biotechnology Technische Universität Berlin , 13355 Berlin , Germany., Pelzing M; Analytical Biochemistry, CSL Limited , Bio21 Institute , 30 Flemington Road , 3010 Parkville, Melbourne , Australia., Petrotchenko E; University of Victoria-Genome British Columbia Proteomics Centre , Vancouver Island Technology Park , Victoria , British Columbia V8Z 7X8 , Canada., Piersimoni L; Departments of Biological Chemistry, Bioinformatics, and Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States., Plasencia M; Departments of Biological Chemistry, Bioinformatics, and Chemistry , University of Michigan , Ann Arbor , Michigan 48109 , United States., Pukala T; Discipline of Chemistry, Faculty of Sciences , University of Adelaide , North Terrace, Adelaide , South Australia 5005 , Australia., Rand KD; Department of Pharmacy , University of Copenhagen , 2100 Copenhagen , Denmark., Rappsilber J; Chair of Bioanalytics, Institute of Biotechnology Technische Universität Berlin , 13355 Berlin , Germany.; Wellcome Trust Centre for Cell Biology, School of Biological Sciences , University of Edinburgh , EH9 3BF Edinburgh , U.K., Reichmann D; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, Safra Campus Givat Ram , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel., Sailer C; University of Konstanz , Department of Biology , Universitätsstrasse 10 , 78457 Konstanz , Germany., Sarnowski CP; Department of Biology, Institute of Molecular Systems Biology , ETH Zurich , Otto-Stern-Weg 3 , 8093 Zurich , Switzerland.; PhD Program in Systems Biology , University of Zurich and ETH Zurich , 8092 Zurich , Switzerland., Scheltema RA; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences , University of Utrecht and Netherlands Proteomics Centre , Padualaan 8 , 3584 CH Utrecht , The Netherlands., Schmidt C; Interdisciplinary Research Center HALOmem, Institute for Biochemistry and Biotechnology, Charles Tanford Protein Center , Martin Luther University Halle-Wittenberg , Kurt-Mothes-Strasse 3a , 06120 Halle/Saale , Germany., Schriemer DC; Department of Biochemistry & Molecular Biology, Robson DNA Science Centre , University of Calgary , 3330 Hospital Drive North West , Calgary , Alberta T2N 4N1 , Canada., Shi Y; Department of Cell Biology , University of Pittsburgh, School of Medicine , Pittsburgh , Pennsylvania 15213 , United States., Skehel JM; MRC Laboratory of Molecular Biology , Cambridge Biomedical Campus , Francis Crick Avenue , Cambridge CB2 0QH , U.K., Slavin M; Department of Biological Chemistry, The Alexander Silberman Institute of Life Sciences, Safra Campus Givat Ram , The Hebrew University of Jerusalem , Jerusalem 91904 , Israel., Sobott F; Department of Chemistry , University of Antwerp , Groenenborgerlaan 171 , 2020 Antwerp , Belgium.; The Astbury Centre for Structural Molecular Biology and School of Molecular and Cellular Biology , University of Leeds , LS2 9JT Leeds , U.K., Solis-Mezarino V; Gene Center Munich, Department of Biochemistry, Faculty of Chemistry and Pharmacy , Ludwig Maximilians University of Munich , Feodor-Lynen-Strasse 25 , 81377 Munich , Germany., Stephanowitz H; Leibniz Institute of Molecular Pharmacology (FMP) , Robert-Rössle-Strasse 10 , 13125 Berlin , Germany., Stengel F; University of Konstanz , Department of Biology , Universitätsstrasse 10 , 78457 Konstanz , Germany., Stieger CE; Protein Chemistry Facility, Research Institute of Molecular Pathology (IMP) and Institute of Molecular Biotechnology (IMBA) , Vienna Biocenter (VBC) , Dr. Bohr-Gasse 3 , 1030 Vienna , Austria., Trabjerg E; Department of Pharmacy , University of Copenhagen , 2100 Copenhagen , Denmark., Trnka M; UCSF Mass Spectrometry Facility , Genentech Hall, 600 16th Street , San Francisco , California 94158 , United States., Vilaseca M; Institute for Research in Biomedicine (IRB Barcelona) , The Barcelona Institute of Science and Technology (BIST) , Baldiri Reixac 10 , 08028 Barcelona , Spain., Viner R; Thermo Fisher Scientific , 355 River Oaks Parkway , San Jose , California 95134 , United States., Xiang Y; Department of Cell Biology , University of Pittsburgh, School of Medicine , Pittsburgh , Pennsylvania 15213 , United States., Yilmaz S; Computational Systems Biochemistry Research Group , Max-Planck-Institute of Biochemistry , Am Klopferspitz 18 , 82152 Martinsried , Germany., Zelter A; Department of Biochemistry , University of Washington , Seattle , Washington 98195 , United States., Ziemianowicz D; Department of Biochemistry & Molecular Biology, Robson DNA Science Centre , University of Calgary , 3330 Hospital Drive North West , Calgary , Alberta T2N 4N1 , Canada., Leitner A; Department of Biology, Institute of Molecular Systems Biology , ETH Zurich , Otto-Stern-Weg 3 , 8093 Zurich , Switzerland., Sinz A; Department of Pharmaceutical Chemistry and Bioanalytics, Institute of Pharmacy, Charles Tanford Protein Center , Martin Luther University Halle-Wittenberg , Kurt-Mothes-Strasse 3a , 06120 Halle/Saale , Germany.

Publikováno v: Analytical chemistry [Anal Chem] 2019 Jun 04; Vol. 91 (11), pp. 6953-6961. Date of Electronic Publication: 2019 May 22.

Tissue damaging toxins in snake venoms: mechanisms of action, pathophysiology and treatment strategies.

Autor: Bittenbinder, Mátyás A.^1,2,3 (AUTHOR), van Thiel, Jory^4,5,6 (AUTHOR), Cardoso, Fernanda C.^7,8 (AUTHOR), Casewell, Nicholas R.⁴ (AUTHOR), Gutiérrez, José-María⁹ (AUTHOR) jose.gutierrez@ucr.ac.cr, Kool, Jeroen^2,3 (AUTHOR) j.kool@vu.nl, Vonk, Freek J.^1,2,3 (AUTHOR)

Publikováno v: Communications Biology. 3/22/2024, Vol. 7 Issue 1, p1-17. 17p.