Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Neva J. Fudge"'
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1204 (2023)
Background: Cerebrospinal fluid (CSF) is an important sampling site for putative biomarkers and contains immune cells. CXCL10 is a multiple sclerosis (MS)-relevant chemokine that is present in the injured central nervous system and recruits CXCR3+ im
Externí odkaz:
https://doaj.org/article/802195c8152c4998924c2517a543298c
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Extracellular vesicles (EVs) are secreted from cells under physiological and pathological conditions, and are found in biological fluids while displaying specific surface markers that are indicative of their cell of origin. EVs have emerged as import
Externí odkaz:
https://doaj.org/article/1f2de43b73484536be579f5f03ba8d34
Publikováno v:
Viruses, Vol 11, Iss 3, p 239 (2019)
Expansion of natural killer (NK) cells expressing NKG2C occurs following human cytomegalovirus (HCMV) infection and is amplified by human immunodeficiency virus (HIV) co-infection. These NKG2C-expressing NK cells demonstrate enhanced CD16-dependent c
Externí odkaz:
https://doaj.org/article/52b3dc1a385c4668858e8b640e649a46
Autor:
Dylan A. Galloway, Samantha J. Carew, Stephanie N. Blandford, Rochelle Y. Benoit, Neva J. Fudge, Tangyne Berry, George R. Wayne Moore, Jane Barron, Craig S. Moore
Publikováno v:
Journal of Neurochemistry. 163:94-112
Innate immune signaling pathways are essential mediators of inflammation and repair following myelin injury. Inflammasome activation has recently been implicated as a driver of myelin injury in multiple sclerosis (MS) and its animal models, although
Publikováno v:
Viruses
Viruses; Volume 13; Issue 11; Pages: 2321
Viruses, Vol 13, Iss 2321, p 2321 (2021)
Viruses; Volume 13; Issue 11; Pages: 2321
Viruses, Vol 13, Iss 2321, p 2321 (2021)
Reducing the socioeconomic toll from age-related physical and mental morbidities requires better understanding of factors affecting healthy aging. While many environmental, lifestyle, and genetic factors affect healthy aging, this study addressed the
Publikováno v:
Frontiers in immunology. 13
Extracellular vesicles (EVs) are secreted from cells under physiological and pathological conditions, and are found in biological fluids while displaying specific surface markers that are indicative of their cell of origin. EVs have emerged as import
Publikováno v:
Viruses
Volume 11
Issue 3
Viruses, Vol 11, Iss 3, p 239 (2019)
Volume 11
Issue 3
Viruses, Vol 11, Iss 3, p 239 (2019)
Expansion of natural killer (NK) cells expressing NKG2C occurs following human cytomegalovirus (HCMV) infection and is amplified by human immunodeficiency virus (HIV) co-infection. These NKG2C-expressing NK cells demonstrate enhanced CD16-dependent c
Autor:
Philippe Beauchemin, Manu Rangachari, Arnaud Droit, Mickael Leclercq, Gian Filipo Ruda, Muhammad Umair, Asmita Pradeep Yeola, Paul Brennan, Ana C. Anderson, Melanie Alpaugh, Reda Fazazi, Joanie Baillargeon, John B. Williams, Hans Lassmann, Prenitha Mercy Ignatius Arokia Doss, Charles Joly-Beauparlant, Neva J. Fudge, Irshad Akbar, Craig S. Moore
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108833-(2021)
Summary Sex differences in multiple sclerosis (MS) incidence and severity have long been recognized. However, the underlying cellular and molecular mechanisms for why male sex is associated with more aggressive disease remain poorly defined. Using a
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Antiretroviral therapy (ART) effectively extends the life expectancy of human immunodeficiency virus (HIV)-infected individuals; however, age-related morbidities have emerged as major clinical concerns. In this context, coinfection with cytomegalovir
Publikováno v:
European journal of immunology. 47(6)
Natural killer (NK) cells are cytotoxic lymphocytes that selectively respond against abnormal cells. Human cytomegalovirus (HCMV) infection causes expansion of NKG2C+ CD57+ NK cells in vivo and NKG2C+ NK cells proliferate when cultured with HCMV-infe