Efficacy and Safety of Epratuzumab in Moderately to Severely Active Systemic Lupus Erythematosus: Results From Two Phase III Randomized, Double-Blind, Placebo-Controlled Trials

Autor: Clowse, Megan E. B, Wallace, Daniel J., Furie, Richard A., Petri, Michelle A., Pike, Marilyn C., Leszczyński, Piotr, Neuwelt, C. Michael, Hobbs, Kathryn, Keiserman, Mauro, Duca, Liliana, Kalunian, Kenneth C., Galateanu, Catrinel, Bongardt, Sabine, Stach, Christian, Beaudot, Carolyn, Kilgallen, Brian, Gordon, Caroline, Batalov, A., Bojinca, M., Djerassi, R., Duca, L., Horak, P., Kolarov, Z., Milasiene, R., Monova, D., Otsa, K., Pileckyte, M., Popova, T., Radulescu, F., Rashkov, R., Rednic, S., Repin, M., Stoilov, R., Tegzova, D., Vezikova, N., Vitek, P., Zainea, C., East, Far, Baek, H., Chen, Y., Chiu, Y., Cho, C., Chou, C., Choe, J., Huang, C., Kang, Y., Kang, S., Lai, N., Lee, S., Park, W., Shim, S., Suh, C., Yoo, W., Armengol, H. Avila, Zapata, F. Avila, Santiago, M. Barreto, Cavalcanti, F., Chahade, W., Costallat, L., Keiserman, M., Alcala, J. Orozco, Remus, C. Ramos, Roimicher, L., Abu Shakra, M., Agarwal, V., Agmon Levin, N., Kadel, J., Levy, Y., Mevorach, D., Paran, D., Reitblat, T., Rosner, I., Shobha, V., Sthoeger, Z., Zisman, D., Ayesu, K., Berney, S., Box, J., Busch, H., Buyon, J., Carter, J., Chi, J., Clowse, M., Collins, R., Dao, K., Diab, I., Dikranian, A., El Shahawy, M., Gaylis, N., Grossman, J., Halpert, E., Huff, J., Jarjour, W., Kao, A., Katz, R., Kennedy, A., Khan, M., Kivitz, A., Kohen, M., Lawrence Ford, T., Lawson, J., Levesque, M., Lowenstein, M., Majjhoo, A., Mcarthur, R., Mclain, D., Merrill, J., Murillo, A., Neucks, S., Niemer, G., Noaiseh, G., Parker, C., Pantojas, C., Pattanaik, D., Petri, M., Pickrell, P., Reveille, J., Roman Miranda, A., Rothfield, N., Sankoorikal, A., Sayers, M., Singhal, A., Snyder, A., Striebich, C., Vo, Q., von Feldt, J., Wallace, D., Wasko, M., Young, C., Adelstein, S., Hall, S., Littlejohn, G., Nicholls, D., Suranyi, M., Amoura, Z., Bannert, B., Behrens, F., Perez, L. Carreno, Chakravarty, K., Gonzales, F. Diaz, Davies, K., Doria, Andrea, Emery, P., Fernández Nebro, A., Govoni, M., Hachulla, E., Hellmich, B., Houssiau, F., Malaise, M., Margaux, J., Maugars, Y., Muñoz Fernández, S., Navarro, F., Ordi Ros, J., Pellerito, R., Pena Sagredo, J., Roussou, E., Schmidt, R. E., Ucar Angulo, E., Viallard, J. F., Westhovens, R., Worm, M., Yee, C. S., Nayiager, S., Reuter, H., Spargo, C., Bazela, B., Brzosko, M., Chudzik, D., Gasztonyi, B., Geher, P., Ionescu, R., Jeka, S., Kemeny, L., Kiss, E., Kotyla, P., Kovacs, L., Kovalenko, V., Kucharz, E., Kwiatkowska, B., Leszczynski, P., Levchenko, E., Lysenko, G., Majdan, M., Mihailov, C., Nalotov, S., Nedelciu, M., Pavel, M., Raskina, T., Rebrov, B., Rezus, E., Semen, T., Smakotina, S., Stanislavchuk, M., Stanislav, M., Szombati, I., Szucs, G., Udrea, G., Zajdel, J., Zon Giebel, A., Bonfiglioli, R., Bustamante, R., Klumb, E., Ramirez, G. Medrano, Neiva, C., Olguin, M., Gonzaga, J. Reyes, Scotton, A., Ayala, S. Sicsik, Ximenes, A., Sharma, R., Srikantiah, C., Aelion, J., Aranow, C., Baker, M., Chadha, A., Chao, J., Chatham, W., Chow, A., Clay, C., Cohen Gadol, S., Conaway, D., Denburg, J., Escalante, A., Espinoza, L., Fiechtner, J., Fortin, I., Fraser, A., Furie, R., Gladman, D., Goddard, D., Goldberg, M., Gonzalez Rivera, R., Gorman, J., Griffin, R., Haaland, D., Halter, D., Hemaiden, A., Hobbs, K., Joshi, V., Lim, S., Kalunian, K., Karpouzas, G., Khraishi, M., Lafyatis, R., Lidman, R., Lue, C., Mohan, M., Mease, P., Mehta, C., Mizutani, W., Nami, A., Nascimento, J., Neuwelt, C., Pappas, J., Pope, J., Porges, A., Roane, G., Rosenberg, D., Ross, S., Saadeh, C., Scoville, C., Sherrer, Y., Solomon, M., Surbeck, W., Valenzuela, G., Waller, P., Alten, R., Baerwald, C., Bienvenu, B., Bombardieri, S., Braun, J., Dival, L., Espinosa, G., Fernandez, I. Figueroa, Gomez Reino, J., Gordon, C., Hiepe, F., Hopkinson, N., Isenberg, D., Jacobi, A., Jorgensen, C., Guern, V. Le, Paul, C., Pego Reigosa, J. M., Heredia, J. Rodriguez, Rubbert Roth, A., Sabbadini, M., Schroeder, J., Schwarting, A., Spieler, W., Valesini, G., Wollenhaupt, J., Mendoza, A. Zea, Zouboulis, C.

Publikováno v: Arthritis & Rheumatology (Hoboken, N.j.)

Objective Epratuzumab, a monoclonal antibody that targets CD22, modulates B cell signaling without substantial reductions in the number of B cells. The aim of this study was to report the results of 2 phase III multicenter randomized, double‐blind,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f2cf21ab295304e86558058503bbae0f
http://hdl.handle.net/11573/1152010

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Long‐Term Safety of Rituximab in Patients With Rheumatoid Arthritis: Results of a Five‐Year Observational Study

Autor: Winthrop, Kevin L., Saag, Kenneth, Cascino, Matthew D., Pei, Jinglan, John, Ani, Jahreis, Angelika, Haselkorn, Tmirah, Furst, Daniel E., Abdulky, M., Abeles, M., Adelglass, H., Ahmed, A., Alloway, J., Alper, J., Anand, A., Anderson, J., Arora, M., Askari, A., Baca, S., Bacha, D., Bagheri, S., Ballou, S., Bennett, R., Bidula, L., Blumstein, H., Bognar, M., Bohan, A., Boniske, C., Borofsky, M., Box, E., Braun, A., Brennan, T., Brent, L., Cabalar, I., Carteron, N., Chaudhary, K., Chauhan, A., Cima, M., Cochinwala, A., Cohen, H., Colburn, K., Conaway, D., Danning, C., Dao, K., Dean, J., Diab, I., Diegel, R., Ditzian‐Kadanoff, R., Dowd, J., Dugowson, C., Eggebeen, A., El‐Kadi, H., Feinberg, H., Feinman, M., Feinstein, J., Fischer, A., Foad, B., Fondal, M., Fraser, S., Fraser, A., Freeman, P., Garber, M., Goldstein, A., Golombek, S., Greenstein, N., Greenwald, M., Hakim, C., Halla, J., Hallegua, D., Han, K., Harris, B., Hauptman, H., Hirsh, J., Hoffman, M., Huntwork, J., Husni, M., Hyer, F., Hymowitz, R., Jones, R., Kanagasegar, S., Kappes, J., Keating, R., Kelly, G., Kim, J., King, C., Klashman, D., Knee, C., Kolba, K., Krick, G., Krug, H., Kumar, U., Lakhanpal, S., Lang, T., Lauter, S., Lawrence Ford, T., Lee, W., Lee, Y., Leisen, J., Levine, J., Lidman, R., Lipstate, J., Malinak, J., Marcus, R., Martin, D., Mehta, C., Melton, G., Metyas, S., Miller, K., Moidel, R., Moore, C., Mossell, J., Munoz, G., Murphy, F., Nami, A., Nascimento, J., Neal, N., Neiman, R., Neuwelt, C., Nguyen, P., Niemer, M., Oelke, K., Oza, M., Pachaidee, S., Patel, S., Pegram, S., Penmetcha, M., Perkins, J., Perl, A., Peterson, L., Pittsley, R., Portnoff, K., Rahmani, D., Raja, N., Ratnoff, W., Rezaian, M., Rhea, C., Rice, D., Ridley, D., Rivadeneira, A., Rizzo, W., Roane, G., Rocca, P., Rosen, M., Saikali, W., Saitta, M., Sankoorikal, A., Saway, P., Schneider, P., Schwartzman, S., Scoville, C., Shergy, W., Shiel, W, Shurmur, R., Sikes, D., Singhal, A., Snyder, A., Songcharoen, S., Sosenko, M., Soto Raices, O., Stahl, N., Stark, K., Strachan, M., Stupi, A., Sullivan, N., Sylvester, R., Tabechian, D., Tagoe, C., Taylor, P., Thakker, S., Thakor, M., Thakur, N., Tidmore, W., Toth, M., Trostle, D., Udell, J., Van de Stouwe, M., Venuturupalli, R., Weiss, D., Weselman, K., Winn, D., Yung, C., Zable, E., Zamiri, B.

Publikováno v: Arthritis Care and Research; August 2019, Vol. 71 Issue: 8 p993-1003, 11p

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