Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Neutrophils/drug effects/ metabolism"'
1
The soluble curcumin derivative NDS27 inhibits superoxide anion production by neutrophils and acts as substrate and reversible inhibitor of myeloperoxidase
Autor: Iyas Aldib, Pierre Van Antwerpen, Ange Mouithys-Mickalad, Philippe Neven, Martine Prévost, Christian Obinger, Didier Serteyn, Thierry Franck, Jalal Soubhye, Karim Zouaoui Boudjeltia, Paul G. Furtmüller
Publikováno v: Chemico-biological interactions, 297
A water-soluble curcumin lysinate incorporated into hydroxypropyl-β-cyclodextrin (NDS27) has been developed and shown anti-inflammatory properties but no comparative study has been made in parallel with its parent molecule, curcumin on polymorphonuc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4253eccbac363aab7f42097e3994168a
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/300405
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2
Mouse neutrophils express the decoy type 2 interleukin-1 receptor (IL-1R2) constitutively and in acute inflammatory conditions
Autor: Gaby Palmer, Céline Lamacchia, Solenne Vigne, Stefan Rose-John, Praxedis Martin, Emiliana Rodriguez, Cem Gabay, Dominique Talabot-Ayer, Athena Chalaris
Publikováno v: Journal of leukocyte biology
Journal of leukocyte biology, Vol. 94, No 4 (2013) pp. 791-802
The proinflammatory activities of IL-1 are tightly controlled at different levels. IL-1R2 acts as a decoy receptor and has been shown to regulate the biological effects of IL-1 in vitro and in vivo. However, little is known about its natural expressi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6bcdaf7d79202c5c5b868e2a0d91a6
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3
Granule-specific ATP requirements for Ca2+-induced exocytosis in human neutrophils. Evidence for substantial ATP-independent release
Autor: Sten Theander, Olivier Nusse, Daniel Pablo Lew
Publikováno v: Journal of Cell Science, Vol. 115, No Pt 14 (2002) pp. 2975-2983
Ca2+-induced exocytosis in neuronal and neuroendocrine cells involves ATP-dependent steps believed to 'prime' vesicles for exocytosis. Primed, docked vesicles are released in response to Ca2+ influx through voltage-gated Ca2+ channels. Neutrophils, h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1808578d48b8cfe9e824e3fe4d76656
https://doi.org/10.1242/jcs.115.14.2975
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4
Characterization of receptor-mediated and store-regulated Ca2+ influx in human neutrophils
Autor: Antoinette Monod, Daniel Pablo Lew, Nicolas Demaurex, Karl-Heinz Krause
Publikováno v: Biochemical Journal, Vol. 297 ( Pt 3) (1994) pp. 595-601
1. It is not known to what extent the emptying of intracellular Ca2+ stores participates in the mediation of chemoattractant-induced Ca2+ influx in human neutrophils. To study this question, we compared the properties of bivalent-cation influx in res
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b88b44dc9fad0070e6d479190afa6e
https://doi.org/10.1042/bj2970595
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5
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action
Autor: Yvonne Westermaier, Leonardo Scapozza, William M. Nauseef, Julien Marcoux, Karl-Heinz Krause, Sally McCormick, Karen Bedard, Remo Perozzo, Becky A. Diebold, Kevin G. Leidal, Vincent Jaquet, Laetitia Fioraso-Cartier, Olivier Plastre, Eric Forest, Franck Fieschi
Publikováno v: British Journal of Pharmacology, Vol. 164, No 2b (2011) pp. 507-20
British Journal of Pharmacology
British Journal of Pharmacology, Wiley, 2011, 164 (2b), pp.507-520. ⟨10.1111/j.1476-5381.2011.01439.x⟩
British Journal of Pharmacology, 2011, 164 (2b), pp.507-520. ⟨10.1111/j.1476-5381.2011.01439.x⟩
International audience; BACKGROUND Celastrol is one of several bioactive compounds extracted from the medicinal plant Tripterygium wilfordii. Celastrol is used to treat inflammatory conditions, and shows benefits in models of neurodegenerative diseas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e10874075658d656a4bfec648fe107
https://pubmed.ncbi.nlm.nih.gov/21501142
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6
Gelsolin-actin interaction and actin polymerization in human neutrophils
Autor: Christine Chaponnier, Thomas P. Stossel, Helen L. Yin, T. Howard
Publikováno v: The Journal of Cell Biology, Vol. 110, No 6 (1990) pp. 1983-1991
The Journal of Cell Biology
The fraction of polymerized actin in human blood neutrophils increases after exposure to formyl-methionyl-leucyl-phenylalanine (fmlp), is maximal 10 s after peptide addition, and decreases after 300 s. Most of the gelsolin (85 +/- 11%) in resting fic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b3e969edf0c34b17188c1ff0c75f64
https://doi.org/10.1083/jcb.110.6.1983
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7
Gelsolin-actin complex is target for ADP-ribosylation by Clostridium botulinum C2 toxin in intact human neutrophils
Autor: Micaella Wille, Ingo Just, Klaus Aktories, Christine Chaponnier
Publikováno v: European Journal of Pharmacology, Vol. 246, No 3 (1993) pp. 293-297
The gelsolin-actin complex was ADP-ribosylated by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin in lysates of human platelets and human neutrophils. When [32P]orthophosphate-labelled human neutrophils were treated with C. botu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4a8f5f42e104a1f6edc014cbc64f07
https://archive-ouverte.unige.ch/unige:10928
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8
Differential effects on neutrophil activation of staurosporin and its protein kinase C-selective derivative cgp 41231
Autor: Elzbieta Huggler, Daniel Pablo Lew, Karl-Heinz Krause, Christian van Delden, Antoinette Monod
Publikováno v: European Journal of Pharmacology, Vol. 227, No 2 (1992) pp. 221-224
The relative insensitivity of the chemoattractant-induced respiratory burst to non-specific kinase inhibitors, such as staurosporin, is widely considered as evidence against the involvement of protein kinase C in signal transduction by chemoattractan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ab25c20aa9756f75e255b36b2a460d
https://archive-ouverte.unige.ch/unige:9381
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9
Receptor-mediated phagocytosis in human neutrophils is associated with increased formation of inositol phosphates and diacylglycerol. Elevation in cytosolic free calcium and formation of inositol phosphates can be dissociated from accumulation of diacylglycerol
Autor: Tommy Andersson, Daniel Pablo Lew, Maria Fällman, O. Stendahl
Publikováno v: Journal of Clinical Investigation, Vol. 84, No 3 (1989) pp. 886-891
Phagocytosis of C3bi- or IgG-opsonized yeast particles in human neutrophils was found to be associated with an increased formation of inositol phosphates and diacylglycerol. Pertussis toxin only marginally affected phagocytosis of IgG- and C3bi-opson
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148024c3f9f2ff2258d227cabebfaac5
https://europepmc.org/articles/PMC329732/
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10
Protein kinase C activation of physiological processes in human neutrophils at vanishingly small cytosolic Ca2+ levels
Autor: F Di Virgilio, Daniel Pablo Lew, Tullio Pozzan
Publikováno v: Nature, Vol. 310, No 5979 (1984) pp. 691-693
It has long been assumed that a rise in cytosolic free Ca2+, [Ca2+]i, is a necessary and sufficient event for the stimulation of a variety of cellular processes. The development of a technique which allows monitoring of [Ca2+]i in small intact cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7cb85465f25d9f79d31c71207b9ec6
https://pubmed.ncbi.nlm.nih.gov/6236373
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