Understanding the role of RIPK1 kinase activity in atherogenesis: a genetic versus pharmacological approach.

Autor: Puylaert, P, Coornaert, I, Neutel, CHG, Bertrand, MJM, Guns, PJ, Meyer, GRY De, Martinet, W

Publikováno v: Cardiovascular Research; 2022 Supplement, Vol. 118, p1-1, 1p

Calciprotein particles induce arterial stiffening ex vivo and impair vascular cell function.

Autor: Neutel CHG; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium. cedric.neutel@uantwerpen.be., Wesley CD; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., van Loo C; Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands., Civati C; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Mertens F; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Zurek M; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Verhulst A; Laboratory of Pathophysiology, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Pintelon I; Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.; Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium.; µNEURO Research Excellence Consortium On Multimodal Neuromics, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium., De Vos WH; Laboratory of Cell Biology and Histology, University of Antwerp, Antwerp, Belgium.; Antwerp Centre for Advanced Microscopy (ACAM), University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium.; µNEURO Research Excellence Consortium On Multimodal Neuromics, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium., Spronck B; Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, the Netherlands., Roth L; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., De Meyer GRY; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Martinet W; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium., Guns PJ; Laboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.

Publikováno v: Communications biology [Commun Biol] 2024 Oct 02; Vol. 7 (1), pp. 1241. Date of Electronic Publication: 2024 Oct 02.

Increasing pulse pressure ex vivo, mimicking acute physical exercise, induces smooth muscle cell-mediated de-stiffening of murine aortic segments.

Autor: Neutel CHG; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium. Cedric.Neutel@uantwerpen.be., Weyns AS; Natural Products & Food Research and Analysis-Pharmaceutical Technology (NatuRA-PT), University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., Leloup A; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., De Moudt S; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., Guns PJ; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., Fransen P; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium.

Publikováno v: Communications biology [Commun Biol] 2023 Nov 09; Vol. 6 (1), pp. 1137. Date of Electronic Publication: 2023 Nov 09.

The effect of cyclic stretch on aortic viscoelasticity and the putative role of smooth muscle focal adhesion.

Autor: Neutel CHG; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., Wesley CD; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., De Meyer GRY; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., Martinet W; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium., Guns PJ; Laboratory of Physiopharmacology, University of Antwerp, Campus Drie Eiken, Antwerp, Belgium.

Publikováno v: Frontiers in physiology [Front Physiol] 2023 Aug 11; Vol. 14, pp. 1218924. Date of Electronic Publication: 2023 Aug 11 (Print Publication: 2023).

The Impact of RIPK1 Kinase Inhibition on Atherogenesis: A Genetic and a Pharmacological Approach.

Autor: Puylaert P; Laboratory of Physiopharmacology, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., Coornaert I; Laboratory of Physiopharmacology, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., Neutel CHG; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., Dondelinger Y; VIB Center for Inflammation Research, 9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium., Delanghe T; VIB Center for Inflammation Research, 9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium., Bertrand MJM; VIB Center for Inflammation Research, 9052 Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, 9052 Ghent, Belgium., Guns PJ; Laboratory of Physiopharmacology, Faculty of Medicine and Health Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., De Meyer GRY; Laboratory of Physiopharmacology, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium., Martinet W; Laboratory of Physiopharmacology, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium.

Publikováno v: Biomedicines [Biomedicines] 2022 Apr 28; Vol. 10 (5). Date of Electronic Publication: 2022 Apr 28.