Zobrazeno 1 - 10
of 192
pro vyhledávání: '"Neurons/drug effects"'
Autor:
M.C.T Verheijen, J. Krauskopf, F. Caiment, M. Nazaruk, Q.F. Wen, M.H.M. van Herwijnen, D.A. Hauser, M. Gajjar, C. Verfaillie, Y. Vermeiren, P.P. De Deyn, M.M.J. Wittens, A. Sieben, S. Engelborghs, W. Dejonckheere, K. Princen, G. Griffioen, E.L. Roggen, J.J. Briedé
Publikováno v:
Toxicology Letters, 356, 89-99. Elsevier Ireland Ltd
Toxicology letters
Toxicology Letters 356 (2022)
Toxicology Letters, 356, 89-99
Toxicology letters
Toxicology Letters 356 (2022)
Toxicology Letters, 356, 89-99
Alzheimer's disease (AD) is the most common cause of dementia, characterized by the progressive impairment of cognition and memory loss. Sporadic AD (sAD) represents approximately 95 % of the AD cases and is induced by a complex interplay between gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3882331ce49c22cc5d5838535349c6d
https://lirias.kuleuven.be/handle/20.500.12942/697974
https://lirias.kuleuven.be/handle/20.500.12942/697974
Autor:
Ferré, Cécile, Thouard, Anne, Bétourné, Alexandre, Le Dorze, Anne-Louise, Belenguer, Pascale, Miquel, Marie-Christine, Peyrin, Jean-Michel, Gonzalez-Dunia, Daniel, Szelechowski, Marion
Publikováno v:
Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-97162-1⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, 2021, 11 (1), pp.17705. ⟨10.1038/s41598-021-97162-1⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.17705. ⟨10.1038/s41598-021-97162-1⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-021-97162-1⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, 2021, 11 (1), pp.17705. ⟨10.1038/s41598-021-97162-1⟩
Scientific Reports, Nature Publishing Group, 2021, 11 (1), pp.17705. ⟨10.1038/s41598-021-97162-1⟩
International audience; Abstract Mortalin is a mitochondrial chaperone protein involved in quality control of proteins imported into the mitochondrial matrix, which was recently described as a sensor of neuronal stress. Mortalin is down-regulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5bdfacbb75cb9f9458677eb3bc34d63f
https://hal.archives-ouvertes.fr/hal-03424565
https://hal.archives-ouvertes.fr/hal-03424565
Publikováno v:
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 19, Iss 4, Pp 482-489 (2011)
Introduction: Ecstasy or 3,4-Methylenedioxymethamphetamine(MDMA) is a psychotropic and addictive substance that young people tend to use it to reduce their psychological and social tensions. The purpose of this study was to assess the influence of ec
Externí odkaz:
https://doaj.org/article/83deb1eeddf74d269a9769a7ed3a8776
Autor:
Valentin Schmutz, Nicolas Toni, Mari A. Virtanen, Lucas A. Mongiat, Jan Armida, Matteo Bergami, Laszlo Vutskits, Marine Krzisch, Fred H. Gage, Alejandro F. Schinder, Jacqueline Kocher-Braissant, Silvio Gabriel Temprana, Karl-Klaus Conzelmann, Rudolf Kraftsik
Publikováno v:
Brain Structure & Function
Brain structure & function
Brain Structure and Function, vol. 220, no. 4, pp. 2027-2042
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Brain Structure and Function, Vol. 220, No 4 (2015) pp. 2027-2042
Brain structure & function
Brain Structure and Function, vol. 220, no. 4, pp. 2027-2042
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Brain Structure and Function, Vol. 220, No 4 (2015) pp. 2027-2042
The adult dentate gyrus produces new neurons that morphologically and functionally integrate into the hippocampal network. In the adult brain, most excitatory synapses are ensheathed by astrocytic perisynaptic processes that regulate synaptic structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f4ce4747eb262a82ec34c49ed41eaac
http://doc.rero.ch/record/331327/files/429_2014_Article_768.pdf
http://doc.rero.ch/record/331327/files/429_2014_Article_768.pdf
Publikováno v:
Cerebral cortex, vol. 27, no. 6, pp. 3272-3283
Glutamate and K+, both released during neuronal firing, need to be tightly regulated to ensure accurate synaptic transmission. Extracellular glutamate and K+ ([K+]o) are rapidly taken up by glutamate transporters and K+-transporters or channels, resp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf4028fed18da63995eca00777497eb4
http://doc.rero.ch/record/331830/files/CERCOR_27_6_3272.pdf
http://doc.rero.ch/record/331830/files/CERCOR_27_6_3272.pdf
Autor:
Friedrich Borchers, Jochen Kruppa, Florian Lammers-Lietz, Anika Müller, Claudia Spies, Arjen J. C. Slooter, Maria Heinrich, Rudolf Mörgeli, Georg Winterer, Norman Zacharias
Background A pre-existing neurocognitive disorder (NCD) is a relevant factor for the outcome of surgical patients. To improve understanding of these conditions, we investigated the association between parameters of the cholinergic system and NCD. Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca2afea1ad76501f2317172b6a0eb27
https://hdl.handle.net/20.500.14017/119b69b7-5444-447c-980f-acccd95c4933
https://hdl.handle.net/20.500.14017/119b69b7-5444-447c-980f-acccd95c4933
Autor:
Andreas Janata, Kristin L. Schreiber, Caleb D Wilson, Ingrid A.M. Magnet, Tomas Drabek, Patrick M. Kochanek, Jason Stezoski, Keri Janesko-Feldman
Publikováno v:
World Journal of Critical Care Medicine
BACKGROUND Prolonged cardiac arrest (CA) produces extensive neuronal death and microglial proliferation and activation resulting in neuro-cognitive disabilities. Among other potential mechanisms, microglia have been implicated as triggers of neuronal
Autor:
Yue Li, Lucile Marion-Poll, Jérôme Flakowski, Ruud van Zessen, Christian Lüscher, Nicolas Hulo
Publikováno v:
eLife, Vol. 10 (2021) P. e66048
eLife, Vol 10 (2021)
eLife
eLife, Vol 10 (2021)
eLife
Locomotor sensitization (LS) is an early behavioral adaptation to addictive drugs, driven by the increase of dopamine in the Nucleus Accumbens (NAc). However, the effect on accumbal population activity remains elusive. Here, we used single-cell calci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb8483a5701a516c1c25af226be4a26
https://archive-ouverte.unige.ch/unige:158151
https://archive-ouverte.unige.ch/unige:158151
Publikováno v:
Progress in Neurobiology
Progress in Neurobiology, Elsevier, 2020, 194, pp.101888-. ⟨10.1016/j.pneurobio.2020.101888⟩
Progress in neurobiology, vol. 194, pp. 101888
Progress in Neurobiology, Elsevier, 2020, 194, pp.101888-. ⟨10.1016/j.pneurobio.2020.101888⟩
Progress in neurobiology, vol. 194, pp. 101888
Brain lactate formation, intercellular exchange and utilization has been implicated in memory formation. However, the individual role of either neuronal or astroglial monocarboxylate transporters for the acquisition and consolidation of information r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf17c3cb032d051faa32a907a9d81a6
https://hal.archives-ouvertes.fr/hal-03493008
https://hal.archives-ouvertes.fr/hal-03493008
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 8767, p 8767 (2020)
Jensen, N J, Wodschow, H Z, Nilsson, M & Rungby, J 2020, ' Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases ', International Journal of Molecular Sciences, vol. 21, no. 22, 8767 . https://doi.org/10.3390/ijms21228767
International Journal of Molecular Sciences
Jensen, N J, Wodschow, H Z, Nilsson, M & Rungby, J 2020, ' Effects of Ketone Bodies on Brain Metabolism and Function in Neurodegenerative Diseases ', International Journal of Molecular Sciences, vol. 21, no. 22, 8767 . https://doi.org/10.3390/ijms21228767
International Journal of Molecular Sciences
Under normal physiological conditions the brain primarily utilizes glucose for ATP generation. However, in situations where glucose is sparse, e.g., during prolonged fasting, ketone bodies become an important energy source for the brain. The brain’