Výsledky vyhledávání - "Neuronal precursor cells"

Akademický článek

Early Signs of Molecular Defects in iPSC-Derived Neural Stems Cells from Patients with Familial Parkinson’s Disease

Autor: Elissavet Akrioti, Timokratis Karamitros, Panagiotis Gkaravelas, Georgia Kouroupi, Rebecca Matsas, Era Taoufik

Publikováno v: Biomolecules, Vol 12, Iss 7, p 876 (2022)

Parkinson’s disease (PD) is the second most common neurodegenerative disorder, classically associated with extensive loss of dopaminergic neurons of the substantia nigra pars compacta. The hallmark of the disease is the accumulation of pathogenic c

Externí odkaz: https://doaj.org/article/d50ef2417b0c4dbebb7daf98e1249fd3

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Akademický článek

Stem cell therapy role in neurodegenerative disorders

Autor: Pasam Ravisankar, Koppineedi Dhanavardhan, Kompella Prathyusha, Kattula Rao Vinay Rajan

Publikováno v: Archives of Mental Health, Vol 19, Iss 1, Pp 3-8 (2018)

Cellular therapies represent a new frontier in the therapy of neurological diseases. Earlier, regeneration of neurons has been admitted as an impossible event. Thus, neurodegenerative disorders (e.g., Alzheimer's disease, Parkinson's disease, and mul

Externí odkaz: https://doaj.org/article/ba368f2270374c1187d2dd066f88d4ed

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Akademický článek

Specificity and Redundancy of Profilin 1 and 2 Function in Brain Development and Neuronal Structure

Autor: Marina Di Domenico, Melanie Jokwitz, Walter Witke, Pietro Pilo Boyl

Publikováno v: Cells, Vol 10, Iss 9, p 2310 (2021)

Profilin functions have been discussed in numerous cellular processes, including actin polymerization. One puzzling aspect is the concomitant expression of more than one profilin isoform in most tissues. In neuronal precursors and in neurons, profili

Externí odkaz: https://doaj.org/article/b8c10b2efb2f4893bc580d2466104304

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Akademický článek

Fingolimod for Irradiation-Induced Neurodegeneration

Autor: Judith Metzdorf, Zaynab Hobloss, Sibylle Schlevogt, Ilya Ayzenberg, Sarah Stahlke, Xiomara Pedreiturria, Steffen Haupeltshofer, Ralf Gold, Lars Tönges, Ingo Kleiter

Publikováno v: Frontiers in Neuroscience, Vol 13 (2019)

BackgroundCranial irradiation is a common therapy for the treatment of brain tumors, but unfortunately patients suffer from side effects, particularly cognitive impairment, caused by neurodegenerative and neuroinflammatory mechanisms. Finding a thera

Externí odkaz: https://doaj.org/article/1ff3b6d43f3e49c5b4b89b722eaaa9a6

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Akademický článek

Proliferation, Adult Neuronal Stem Cells and Cells Migration in Pallium during Constitutive Neurogenesis and after Traumatic Injury of Telencephalon of Juvenile Masu Salmon, Oncorhynchus masou

Autor: Evgeniya V. Pushchina, Eva I. Zharikova, Anatoly A. Varaksin, Igor M. Prudnikov, Vladimir N. Tsyvkin

Publikováno v: Brain Sciences, Vol 10, Iss 4, p 222 (2020)

A study of the lateral pallium in zebrafish and the visual tectum of the medaka revealed a population of adult neuroepithelial (NE) cells supported from the early stage of development to various postembryonic stages of ontogenesis. These data emphasi

Externí odkaz: https://doaj.org/article/574356c261ef4b49a6670b815b7ada2a

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Akademický článek

Neural Stem Cells/Neuronal Precursor Cells and Postmitotic Neuroblasts in Constitutive Neurogenesis and After ,Traumatic Injury to the Mesencephalic Tegmentum of Juvenile Chum Salmon, Oncorhynchus keta

Autor: Evgeniya V. Pushchina, Ilya A. Kapustyanov, Anatoly A. Varaksin

Publikováno v: Brain Sciences, Vol 10, Iss 2, p 65 (2020)

The proliferation of neural stem cells (NSCs)/neuronal precursor cells (NPCs) and the occurrence of postmitotic neuroblasts in the mesencephalic tegmentum of intact juvenile chum salmon, Oncorhynchus keta, and at 3 days after a tegmental injury, were

Externí odkaz: https://doaj.org/article/b3f3badc8ac6437bb294b6f88a3289c5

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Akademický článek

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Akademický článek

MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex

Autor: Wei Zhang, Paul Jong Kim, Zhongcan Chen, Hidayat Lokman, Lifeng Qiu, Ke Zhang, Steven George Rozen, Eng King Tan, Hyunsoo Shawn Je, Li Zeng

Publikováno v: eLife, Vol 5 (2016)

During the development, tight regulation of the expansion of neural progenitor cells (NPCs) and their differentiation into neurons is crucial for normal cortical formation and function. In this study, we demonstrate that microRNA (miR)-128 regulates

Externí odkaz: https://doaj.org/article/aa2bd3fb12e34d8bb2f1789e3fe31d04

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Long-Term Effects of Neural Precursor Cell Transplantation on Secondary Injury Processes and Functional Recovery after Severe Cervical Contusion-Compression Spinal Cord Injury

Autor: Alexander Younsi, Guoli Zheng, Lennart Riemann, Moritz Scherer, Hao Zhang, Mohamed Tail, Maryam Hatami, Thomas Skutella, Andreas Unterberg, Klaus Zweckberger

Publikováno v: International Journal of Molecular Sciences; Volume 22; Issue 23; Pages: 13106
International Journal of Molecular Sciences, Vol 22, Iss 13106, p 13106 (2021)
International Journal of Molecular Sciences

Cervical spinal cord injury (SCI) remains a devastating event without adequate treatment options despite decades of research. In this context, the usefulness of common preclinical SCI models has been criticized. We, therefore, aimed to use a clinical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fcb75533dce1534354f185b19de1b58

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