Zobrazeno 1 - 10
of 8 323
pro vyhledávání: '"Neuronal migration"'
Publikováno v:
Neural Development, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract The last common ancestor of cephalopods and vertebrates lived about 580 million years ago, yet coleoid cephalopods, comprising squid, cuttlefish and octopus, have evolved an extraordinary behavioural repertoire that includes learned behaviou
Externí odkaz:
https://doaj.org/article/0c8fb81262484d9fb118baf3dc3d8ea7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
While the structural organization and molecular biology of neurons are well characterized, the physical process of axonal elongation remains elusive. The classic view posited elongation occurs through the deposition of cytoskeletal elements in the gr
Externí odkaz:
https://doaj.org/article/8779243fdbe54c20808b20e2491bc52c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Radial glia (RG) are the main progenitor cell type in the developing cortex. These cells are highly polarized, with a long basal process spanning the entire thickness of the cortex and acting as a support for neuronal migration. The RG cell terminate
Externí odkaz:
https://doaj.org/article/56e533d700494c6db3c7f55000551592
Autor:
Raddy L. Ramos, Maider Michelena Beltran De Heredia, Yongwei Zhang, Randy F. Stout, Jaafar O. Tindi, Liching Wu, Gary J. Schwartz, Yair M. Botbol, Simone Sidoli, Ankita Poojari, Tammy Rakowski-Anderson, Bridget Shafit-Zagardo
Publikováno v:
Neurobiology of Disease, Vol 199, Iss , Pp 106594- (2024)
Aims: Cytoplasmic dynein heavy chain (DYNC1H1) is a multi-subunit protein complex that provides motor force for movement of cargo on microtubules and traffics them back to the soma. In humans, mutations along the DYNC1H1 gene result in intellectual d
Externí odkaz:
https://doaj.org/article/6c07a9ad44774ed0968d3018b7640dc1
Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function
Autor:
Mami Matsumoto, Katsuyoshi Matsushita, Masaya Hane, Chentao Wen, Chihiro Kurematsu, Haruko Ota, Huy Bang Nguyen, Truc Quynh Thai, Vicente Herranz-Pérez, Masato Sawada, Koichi Fujimoto, José Manuel García-Verdugo, Koutarou D Kimura, Tatsunori Seki, Chihiro Sato, Nobuhiko Ohno, Kazunobu Sawamoto
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1228-1253 (2024)
Abstract In the injured brain, new neurons produced from endogenous neural stem cells form chains and migrate to injured areas and contribute to the regeneration of lost neurons. However, this endogenous regenerative capacity of the brain has not yet
Externí odkaz:
https://doaj.org/article/38a75c2192bc4cdea63491e9304280eb
Autor:
Anna Cavalli, Stefano Giuseppe Caraffi, Susanna Rizzi, Gabriele Trimarchi, Manuela Napoli, Daniele Frattini, Carlotta Spagnoli, Livia Garavelli, Carlo Fusco
Publikováno v:
BMC Medical Genomics, Vol 17, Iss 1, Pp 1-7 (2024)
Abstract Background Thousand and one amino-acid kinase 1 (TAOK1) encodes the MAP3K protein kinase TAO1, which has recently been displayed to be essential for neuronal maturation and cortical differentiation during early brain development. Heterozygou
Externí odkaz:
https://doaj.org/article/5beec6055b924a6e98b954d1773212b0
Akademický článek
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Akademický článek
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Autor:
Chu Jiang, Jun Guan, Xiangrong Tang, Yichun Zhang, Xiangyu Li, Yuting Li, Zhiheng Chen, Jing Zhang, Jia-Da Li
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 18 (2024)
Bisphenol A (BPA) is a widely used plasticizer known to cause various disorders. Despite a global reduction in the use of BPA-containing products, prenatal exposure to low-dose BPA, even those below established safety limits, has been linked to neuro
Externí odkaz:
https://doaj.org/article/80456cf8d2b0408d88635b872909d942
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Rho guanine nucleotide exchange factors (Rho GEFs) activate Rho GTPases, which act as molecular switches regulating various essential cellular functions. This study investigated the role of ARHGEF5, a Rho GEF known for its involvement in cell migrati
Externí odkaz:
https://doaj.org/article/4f6a94a7d3f74a8baab7cfc500e0e30a