Zobrazeno 1 - 10
of 3 045
pro vyhledávání: '"Neuronal injury"'
Autor:
Yujie Zhai, Yi Yuan, Yaru Cui, Xiaoqian Wang, Hua Zhou, Qian Teng, Hongjin Wang, Bohan Sun, Hongliu Sun, Jianhua Tang
Publikováno v:
Brain Research Bulletin, Vol 219, Iss , Pp 111117- (2024)
PTEN-induced kinase 1 (PINK1) autophosphorylation triggers the PINK1/Parkin pathway, which is the main mitophagic pathway in the mammalian nervous system. In the present study, we aimed to mechanistically explore the role of PINK1 in pilocarpine-indu
Externí odkaz:
https://doaj.org/article/d2d929bfaa3a45898c07a19c28931479
Akademický článek
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Publikováno v:
Experimental Gerontology, Vol 194, Iss , Pp 112484- (2024)
Background: Neurotransmitter transport disorders may play a crucial role in Parkinson's Disease (PD), and Solute carrier family 6 member 12 (SLC6A12) encodes a neurotransmitter transporter. However, the relationship between SLC6A12 and PD remains lar
Externí odkaz:
https://doaj.org/article/969caf1d435a474db6665f3258d10ea5
Publikováno v:
Experimental Gerontology, Vol 190, Iss , Pp 112415- (2024)
Background: Lymphocyte antigen 96 (LY96) plays an important role in innate immunity and has been reported to be associated with various neurological diseases. However, its role in Parkinson's disease (PD) remains unclear. Methods: Transcriptome data
Externí odkaz:
https://doaj.org/article/d71897c2f1ff4a95bb8bd12ac5abd8df
Autor:
Jonathan Z. Pan, Zhanqiang Wang, Wei Sun, Peipei Pan, Wei Li, Yongtao Sun, Shoulin Chen, Amity Lin, Wulin Tan, Liangliang He, Jacob Greene, Virginia Yao, Lijun An, Rich Liang, Qifeng Li, Jessica Yu, Lingyi Zhang, Nikolaos Kyritsis, Xuan Duong Fernandez, Sara Moncivais, Esmeralda Mendoza, Pamela Fung, Gongming Wang, Xinhuan Niu, Qihang Du, Zhaoyang Xiao, Yuwen Chang, Peiyuan Lv, J. Russell Huie, Abel Torres‐Espin, Adam R. Ferguson, Debra D. Hemmerle, Jason F. Talbott, Philip R. Weinstein, Lisa U. Pascual, Vineeta Singh, Anthony M. DiGiorgio, Rajiv Saigal, William D. Whetstone, Geoffrey T. Manley, Sanjay S. Dhall, Jacqueline C. Bresnahan, Mervyn Maze, Xiangning Jiang, Neel S. Singhal, Michael S. Beattie, Hua Su, Zhonghui Guan
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 4, Pp n/a-n/a (2024)
Abstract Background Although many molecules have been investigated as biomarkers for spinal cord injury (SCI) or ischemic stroke, none of them are specifically induced in central nervous system (CNS) neurons following injuries with low baseline expre
Externí odkaz:
https://doaj.org/article/05f71d729fcf4e4b9ab7f2a840ded879
Publikováno v:
Journal of Advanced Research, Vol 52, Iss , Pp 119-134 (2023)
Introduction: Dietary oligosaccharides can impact the gut microbiota and confer tremendous health benefits. Objectives: The aim of this study was to determine the impact of a novel functional oligosaccharide, neoagarotetraose (NAT), on aging in mice.
Externí odkaz:
https://doaj.org/article/f6a94fd94cb744399a47081d566d9775
Autor:
Bachtiar Rivai, Abd. Kakhar Umar
Publikováno v:
Beni-Suef University Journal of Basic and Applied Sciences, Vol 12, Iss 1, Pp 1-19 (2023)
Abstract Background Neuroinflammation is a key pathological feature of a wide variety of neurological disorders, including Parkinson’s, multiple sclerosis, Alzheimer’s, and Huntington’s disease. While current treatments for these disorders are
Externí odkaz:
https://doaj.org/article/d2571cc418564df785125f2906a57997
Autor:
Xia-Jing Zhang, Zhi-Bin Xiao, Jun-Xiang Gu, Kun Chen, Jian Wang, Sheng-Long Xu, Ke-Ke Xing, Tao Chen
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-15 (2023)
Abstract Electromagnetic pulse (EMP), a unique type of electromagnetic radiation, may induce diverse neuropsychiatric disorders, such as irritability, hyperkinesis, retardation of learning and memory. However, the underlying mechanism of EMP exposure
Externí odkaz:
https://doaj.org/article/59a5a4c2069a429083083594ff7ac914
Autor:
Soumya Sucharita Pattnaik, Sudhir Chandra Sarangi, Deeksha Sharma, Surabhi Sinha, Tapas C Nag, Aruna Nambirajan, Manjari Tripathi
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 11, Pp 479-487 (2023)
Objective: To investigate the effect of Ocimum sanctum hydroalcoholic extract (OSHE) on seizure control and neuronal injury in rats with lithium-pilocarpine-induced status epilepticus (SE). Methods: SE was induced by administering lithium chloride fo
Externí odkaz:
https://doaj.org/article/42ceacc6677740ddb2f9a4c706a217a9
Autor:
Yun-Qian Chang, Gui-Juan Zhou, Hong-Mei Wen, Duan-Qun He, Chen-Lin Xu, Ya-Rui Chen, Yi-Hui Li, Shuang-Xi Chen, Zi-Jian Xiao, Ming Xie
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 2, Pp 416-421 (2023)
Radiation therapy is considered the most effective non-surgical treatment for brain tumors. However, there are no available treatments for radiation-induced brain injury. Bisdemethoxycurcumin (BDMC) is a demethoxy derivative of curcumin that has anti
Externí odkaz:
https://doaj.org/article/6c606ece658d4e298da8b0ace3f3db4c