Zobrazeno 1 - 10
of 2 867
pro vyhledávání: '"Neuronal Development"'
Autor:
Yi Kang, Yijie Song, Zhongju Shi, Qiang Li, Yigang Lv, Mengfan Hou, Cui Ding, Jing Xie, Yongfu Lou, Chi Zhang, Huan Jian, Xueying Li, Hengxing Zhou, Shiqing Feng
Publikováno v:
All Life, Vol 17, Iss 1 (2024)
Spinal cord injury (SCI) is a severe event that occurs in the central nervous system (CNS). Long noncoding RNAs (lncRNAs) have already been proven to play key roles in different diseases of the CNS. Nevertheless, the roles of messenger RNAs (mRNAs) a
Externí odkaz:
https://doaj.org/article/e66d9eab497f4c3fa0911cc4f6b529f4
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
Central to the process of axon elongation is the concept of compartmentalized signaling, which involves the A-kinase anchoring protein (AKAP)-dependent organization of signaling pathways within distinct subcellular domains. This spatial organization
Externí odkaz:
https://doaj.org/article/0bb5d04fdb544a33bc16575c5ff5c74b
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-33 (2024)
Abstract Background The functional coupling between alternative pre-mRNA splicing (AS) and the mRNA quality control mechanism called nonsense-mediated decay (NMD) can modulate transcript abundance. Previous studies have identified several examples of
Externí odkaz:
https://doaj.org/article/23d3ae8bceac433f8af4c11f5f4b0477
Chronological transitions of hepatocyte growth factor treatment effects in spinal cord injury tissue
Publikováno v:
Inflammation and Regeneration, Vol 44, Iss 1, Pp 1-11 (2024)
Abstract Inflammatory responses are known to suppress neural regeneration in patients receiving stem cell-based regenerative therapy for spinal cord injury (SCI). Consequently, pathways involved in neurogenesis and immunomodulation, such as the hepat
Externí odkaz:
https://doaj.org/article/45cba96b58ff46dba544d69db81219fb
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Mitochondria are cytoplasmic organelles having a fundamental role in the regulation of neural stem cell (NSC) fate during neural development and maintenance. During embryonic and adult neurogenesis, NSCs undergo a metabolic switch from glyco
Externí odkaz:
https://doaj.org/article/09501709a4dc4768b2d9ff41d23e8c44
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Long non-coding RNAs (lncRNAs) have emerged as critical players in brain development and disease. These non-coding transcripts, which once considered as “transcriptional junk,” are now known for their regulatory roles in gene expression. In brain
Externí odkaz:
https://doaj.org/article/ec7a52afb3cb413ea1e5c3cad3842058
Autor:
Yasmilde Rodríguez González, Fatemeh Kamkar, Paymaan Jafar-nejad, Suzi Wang, Dianbo Qu, Leticia Sanchez Alvarez, Dina Hawari, Margaret Sonnenfeld, Ruth S. Slack, Paul R. Albert, David S. Park, Alvin Joselin
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background PFTK1/Eip63E is a member of the cyclin-dependent kinases (CDKs) family and plays an important role in normal cell cycle progression. Eip63E expresses primarily in postnatal and adult nervous system in Drosophila melanogaster but i
Externí odkaz:
https://doaj.org/article/e34f15bb20044e1ea43c89a1c762ae7a
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundAcute lymphoblastic leukemia (ALL) is prone to metastasize to the central nervous system (CNS), which is an important cause of poor treatment outcomes and unfavorable prognosis. However, the pathogenesis of CNS metastasis of ALL cells has n
Externí odkaz:
https://doaj.org/article/76e01cb5b58249e8b87120b1d0dedd38
Autor:
Yusuke Takatsuru, Kazuya Miyagawa
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/f5f8560db6ce4c47a02eeef5f290fde6
Publikováno v:
Fly, Vol 16, Iss 1, Pp 13-23 (2022)
Dendritic morphogenesis requires dynamic microtubules (MTs) to form a coordinated cytoskeletal network during development. Dynamic MTs are characterized by their number, polarity and speed of polymerization. Previous studies described a correlation b
Externí odkaz:
https://doaj.org/article/748b0a30e668453b8011a17d43fc0e3e