Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Neurology and Preclinical Neurological Studies - Review Article"'
Autor:
Sian-Hülsmann, Jeswinder
Publikováno v:
Journal of Neural Transmission
Parkinson's disease is the second most common neurological disorder marked by characteristic poverty and dysfunction in movement. There are many mechanisms and factors which have been postulated to be associated with the neurodegenerative pathway(s)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412cef0b3e8f5d3ef7c6c0ac505be64d
https://doi.org/10.1007/s00702-021-02448-3
https://doi.org/10.1007/s00702-021-02448-3
Publikováno v:
Journal of Neural Transmission
Protein homeostasis, or proteostasis, is essential for cell function and viability. Unwanted, damaged, misfolded and aggregated proteins are degraded by the ubiquitin–proteasome system (UPS) and the autophagy-lysosome pathway. Growing evidence indi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadce393c60f98c8c9c44084f0d27dd4
https://doi.org/10.1007/s00702-021-02431-y
https://doi.org/10.1007/s00702-021-02431-y
Publikováno v:
Journal of Neural Transmission
Multiple system atrophy (MSA) is a challenging neurodegenerative disorder with a difficult and often inaccurate early diagnosis, still lacking effective treatment. It is characterized by a highly variable clinical presentation with parkinsonism, cere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab407c0ac573aa85ad2500a69bbd4c6
http://europepmc.org/articles/PMC8528757
http://europepmc.org/articles/PMC8528757
Autor:
Alessandra Fanciulli, Gregor K. Wenning, Nadia Stefanova, Stefan Kiechl, Johannes Haybaeck, Nicole Campese
Publikováno v:
Journal of Neural Transmission
Multiple System Atrophy (MSA) is a rare, fatal neurodegenerative disorder. Its etiology and exact pathogenesis still remain poorly understood and currently no disease-modifying therapy is available to halt or slow down this detrimental neurodegenerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d52d867ff3ecc9fa39874397275f321e
http://europepmc.org/articles/PMC8528766
http://europepmc.org/articles/PMC8528766
Publikováno v:
Journal of Neural Transmission
This review honors Kurt Jellinger on his 90th birthday as one of the most outstanding neuropathologists, who has contributed immensely to neuroscience due to his vast experience and collection of excellently documented autopsy cases. Two of his many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efdb07f66e2a2408725080efb0e338b
https://doi.org/10.1007/s00702-021-02358-4
https://doi.org/10.1007/s00702-021-02358-4
Autor:
Johannes Attems, Daniel Erskine
Publikováno v:
Journal of Neural Transmission
Professor Kurt Jellinger is well known for his seminal work on the neuropathology of age-associated neurodegenerative disorders, particularly Lewy body diseases. However, it is less well known that he also contributed important insights into the neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68530db420dc5a9f5383e94e6266a2d
http://europepmc.org/articles/PMC8528771
http://europepmc.org/articles/PMC8528771
Autor:
Alessandro Galgani, Francesco Fornai, Stefano Puglisi-Allegra, Carla L. Busceti, Filippo Sean Giorgi
Publikováno v:
Journal of Neural Transmission
The hypothalamus and Locus Coeruleus (LC) share a variety of functions, as both of them take part in the regulation of the sleep/wake cycle and in the modulation of autonomic and homeostatic activities. Such a functional interplay takes place due to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9d46d265e0268f2e09cdd461a71922
http://europepmc.org/articles/PMC8105225
http://europepmc.org/articles/PMC8105225
Autor:
Norbert Brüggemann
Publikováno v:
Journal of Neural Transmission
Dystonia is a disabling movement disorder characterized by abnormal postures or patterned and repetitive movements due to co-contraction of muscles in proximity to muscles desired for a certain movement. Important and well-established pathophysiologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b748cb294c6186833240878031342183
https://doi.org/10.1007/s00702-021-02299-y
https://doi.org/10.1007/s00702-021-02299-y
Publikováno v:
Journal of Neural Transmission
Complex dystonias are defined as dystonias that are accompanied by neurologic or systemic manifestations beyond movement disorders. Many syndromes or diseases can present with complex dystonia, either as the cardinal sign or as part of a multi-system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c48cf93f6cdb364b044784fd8d3c224d
https://doi.org/10.1007/s00702-020-02275-y
https://doi.org/10.1007/s00702-020-02275-y
Publikováno v:
Journal of Neural Transmission
The thyroid gland is among the organs at the greatest risk of cancer from ionizing radiation. Epidemiological evidence from survivors of radiation therapy, atomic bombing, and the Chernobyl reactor accident, clearly shows that radiation exposure in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::398d35b0d6c0fc75bce94d1825c99292
http://europepmc.org/articles/PMC7578155
http://europepmc.org/articles/PMC7578155