The Legionella effector RavD binds phosphatidylinositol-3-phosphate and helps suppress endolysosomal maturation of the Legionella -containing vacuole.

Autor: Pike CM; From the Delaware Biotechnology Institute and., Boyer-Andersen R; From the Delaware Biotechnology Institute and., Kinch LN; the Howard Hughes Medical Institute, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390., Caplan JL; From the Delaware Biotechnology Institute and.; Departments of Biological Sciences and.; Plant and Soil Sciences, University of Delaware, Newark, Delaware 19716 and., Neunuebel MR; From the Delaware Biotechnology Institute and neunr@udel.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2019 Apr 19; Vol. 294 (16), pp. 6405-6415. Date of Electronic Publication: 2019 Feb 07.

Legionella effector AnkX interacts with host nuclear protein PLEKHN1.

Autor: Yu X; State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences-Beijing (PHOENIX Center), Beijing Institute of Radiation Medicine, Beijing, 102206, China., Noll RR; Department of Biological Sciences, University of Delaware, 105 The Green, Newark, DE, 19716, USA., Romero Dueñas BP; Department of Biological Sciences, University of Delaware, 105 The Green, Newark, DE, 19716, USA., Allgood SC; Department of Biological Sciences, University of Delaware, 105 The Green, Newark, DE, 19716, USA., Barker K; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA., Caplan JL; Department of Biological Sciences, University of Delaware, 105 The Green, Newark, DE, 19716, USA.; Delaware Biotechnology Institute, University of Delaware, Newark, 19716, DE, USA., Machner MP; Cell Biology and Neurobiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, 20892, USA., LaBaer J; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA., Qiu J; Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, AZ, 85287, USA. Ji.Qiu@asu.edu., Neunuebel MR; Department of Biological Sciences, University of Delaware, 105 The Green, Newark, DE, 19716, USA. neunr@udel.edu.

Publikováno v: BMC microbiology [BMC Microbiol] 2018 Jan 05; Vol. 18 (1), pp. 5. Date of Electronic Publication: 2018 Jan 05.

Host-pathogen interaction profiling using self-assembling human protein arrays.

Autor: Yu X; †Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, United States., Decker KB; ‡Unit on Microbial Pathogenesis, Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, United States., Barker K; †Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, United States., Neunuebel MR; ‡Unit on Microbial Pathogenesis, Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, United States., Saul J; †Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, United States., Graves M; †Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, United States., Westcott N; §The Laboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States., Hang H; §The Laboratory of Chemical Biology and Microbial Pathogenesis, The Rockefeller University, New York, New York 10065, United States., LaBaer J; †Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, United States., Qiu J; †Virginia G. Piper Center for Personalized Diagnostics, Biodesign Institute, Arizona State University, Tempe, Arizona 85287, United States., Machner MP; ‡Unit on Microbial Pathogenesis, Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, United States.

Publikováno v: Journal of proteome research [J Proteome Res] 2015 Apr 03; Vol. 14 (4), pp. 1920-36. Date of Electronic Publication: 2015 Mar 18.

Legionella pneumophila LidA affects nucleotide binding and activity of the host GTPase Rab1.

Autor: Neunuebel MR; Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA., Mohammadi S, Jarnik M, Machner MP

Publikováno v: Journal of bacteriology [J Bacteriol] 2012 Mar; Vol. 194 (6), pp. 1389-400. Date of Electronic Publication: 2012 Jan 06.

De-AMPylation of the small GTPase Rab1 by the pathogen Legionella pneumophila.

Autor: Neunuebel MR; Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA., Chen Y, Gaspar AH, Backlund PS Jr, Yergey A, Machner MP

Publikováno v: Science (New York, N.Y.) [Science] 2011 Jul 22; Vol. 333 (6041), pp. 453-6. Date of Electronic Publication: 2011 Jun 16.