TCRpower: quantifying the detection power of T-cell receptor sequencing with a novel computational pipeline calibrated by spike-in sequences.

Autor: Dahal-Koirala S; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, 0372, Norway.; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, 0372, Norway., Balaban G; Biomedical Informatics, Department of Informatics, University of Oslo, 0373, Oslo, Norway.; Department of Computational Physiology, Simula Research Laboratory, 1364, Fornebu, Norway.; PharmaTox Strategic Research Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, 0373, Oslo, Norway., Neumann RS; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, 0372, Norway., Scheffer L; Biomedical Informatics, Department of Informatics, University of Oslo, 0373, Oslo, Norway., Lundin KEA; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, 0372, Norway.; Department of Gastroenterology, Oslo University Hospital-Rikshospitalet, 0372, Oslo, Norway., Greiff V; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, 0372, Norway., Sollid LM; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, 0372, Norway.; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, 0372, Norway., Qiao SW; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, 0372, Norway.; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, Oslo, 0372, Norway., Sandve GK; Biomedical Informatics, Department of Informatics, University of Oslo, 0373, Oslo, Norway.; PharmaTox Strategic Research Initiative, Faculty of Mathematics and Natural Sciences, University of Oslo, 0373, Oslo, Norway.

Publikováno v: Briefings in bioinformatics [Brief Bioinform] 2022 Mar 10; Vol. 23 (2).

Single-cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8 ⁺ αβ T lymphocytes in untreated celiac disease.

Autor: Eggesbø LM; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, Oslo, Norway., Risnes LF; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, Oslo, Norway.; Department of Immunology, University of Oslo and Oslo University Hospital- Rikshospitalet, Oslo, Norway., Neumann RS; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, Oslo, Norway., Lundin KEA; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, Oslo, Norway.; Department of Gastroenterology, Oslo University Hospital-Rikshospitalet, Oslo, Norway., Christophersen A; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, Oslo, Norway., Sollid LM; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, Oslo, Norway.; Department of Immunology, University of Oslo and Oslo University Hospital- Rikshospitalet, Oslo, Norway.

Publikováno v: European journal of immunology [Eur J Immunol] 2021 Jun; Vol. 51 (6), pp. 1542-1545. Date of Electronic Publication: 2021 Feb 26.

T cell receptor repertoire as a potential diagnostic marker for celiac disease.

Autor: Yao Y; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway., Zia A; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway., Neumann RS; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway., Pavlovic M; Department of Informatics, University of Oslo, Norway., Balaban G; Department of Informatics, University of Oslo, Norway., Lundin KEA; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway., Sandve GK; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway; Department of Informatics, University of Oslo, Norway., Qiao SW; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Norway; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Norway. Electronic address: s.w.qiao@medisin.uio.no.

Publikováno v: Clinical immunology (Orlando, Fla.) [Clin Immunol] 2021 Jan; Vol. 222, pp. 108621. Date of Electronic Publication: 2020 Nov 13.

A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease.

Autor: Ting YT; Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; The Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia., Dahal-Koirala S; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway.; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, 0372 Oslo, Norway., Kim HSK; Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; The Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia., Qiao SW; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway.; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, 0372 Oslo, Norway., Neumann RS; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway.; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, 0372 Oslo, Norway., Lundin KEA; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway.; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, 0372 Oslo, Norway.; Department of Gastroenterology, Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway., Petersen J; Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; The Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia., Reid HH; Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.; The Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia., Sollid LM; Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway; l.m.sollid@medisin.uio.no jamie.rossjohn@monash.edu.; K. G. Jebsen Centre for Coeliac Disease Research, University of Oslo, 0372 Oslo, Norway., Rossjohn J; Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; l.m.sollid@medisin.uio.no jamie.rossjohn@monash.edu.; The Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia.; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia.; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, CF14 4XN Cardiff, United Kingdom.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Feb 11; Vol. 117 (6), pp. 3063-3073. Date of Electronic Publication: 2020 Jan 23.

Resident memory CD8 T cells persist for years in human small intestine.

Autor: Bartolomé-Casado R; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway r.b.casado@medisin.uio.no., Landsverk OJB; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway., Chauhan SK; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway.; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway., Richter L; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway.; Core Facility Flow Cytometry, Biomedical Center, Ludwig-Maximilians-University Munich, Munich, Germany., Phung D; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway., Greiff V; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Risnes LF; Department of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway., Yao Y; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway., Neumann RS; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway., Yaqub S; Department of Gastrointestinal Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Øyen O; Department of Transplantation Medicine, Section for Transplant Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Horneland R; Department of Transplantation Medicine, Section for Transplant Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Aandahl EM; Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; Department of Transplantation Medicine, Section for Transplant Surgery, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Paulsen V; Department of Gastroenterology, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Sollid LM; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Immunology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway., Qiao SW; Department of Immunology, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; K.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway., Baekkevold ES; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway., Jahnsen FL; Department of Pathology, Oslo University Hospital and University of Oslo, Oslo, Norway f.l.jahnsen@medisin.uio.no.

Publikováno v: The Journal of experimental medicine [J Exp Med] 2019 Oct 07; Vol. 216 (10), pp. 2412-2426. Date of Electronic Publication: 2019 Jul 23.