Zobrazeno 1 - 10 of 134 pro vyhledávání: '"Neul D"'
1
Akademický článek
Azetidine-based selective glycine transporter-1 (GlyT1) inhibitors with memory enhancing properties.
Autor: Hudson AR; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States. Electronic address: andyrhudson@gmail.com., Santora VJ; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Petroski RE; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Almos TA; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Anderson G; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Barido R; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Basinger J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Bellows CL; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Bookser BC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Broadbent NJ; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Cabebe C; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chai CK; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chen M; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chow S; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Chung M; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Heger L; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Danks AM; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Freestone GC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Gitnick D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Gupta V; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Hoffmaster C; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Kaplan AP; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Kennedy MR; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Lee D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Limberis J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Ly K; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Mak CC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Masatsugu B; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Morse AC; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Na J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Neul D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Nikpur J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Renick J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Sebring K; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Sevidal S; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Tabatabaei A; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Wen J; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Xia S; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Yan Y; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Yoder ZW; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Zook D; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Peters M; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States., Breitenbucher JG; Dart Neuroscience, 12278 Scripps Summit Dr, San Diego, CA 92131, United States.
Publikováno v: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2020 Jul 15; Vol. 30 (14), pp. 127214. Date of Electronic Publication: 2020 Apr 25.
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2
Benzylmorpholine analogs as selective inhibitors of lung cytochrome P450 2A13 for the chemoprevention of lung cancer in tobacco users
Autor: Schoenen, F.J., Roy, A., Neul, D., Aubé, J., Scott, E.E., Blake, L.C.
Purpose: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), one of the most prevalent and procarcinogenic compounds in tobacco, is bioactivated by respiratory cytochrome P450 (CYP) 2A13, forming DNA adducts and initiating lung cancer. CYP2A13 inhi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::54283cc32bbb09d5c7f9c247fd08950a
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3
Akademický článek
CYP3A-Mediated Carbon–Carbon Bond Cleavages in Drug Metabolism.
Autor: Zhou, Junhui1 (AUTHOR) junhui.zhou@bcm.edu, Qin, Xuan1,2 (AUTHOR) xuan.qin@bcm.edu, Zhou, Shenzhi1 (AUTHOR) shenzhi.zhou@bcm.edu, MacKenzie, Kevin R.1,2,3 (AUTHOR) kevin.mackenzie@bcm.edu, Li, Feng1,2,3 (AUTHOR) feng.li@bcm.edu
Publikováno v: Biomolecules (2218-273X). Sep2024, Vol. 14 Issue 9, p1125. 14p.
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5
Akademický článek
Design and Synthesis of Novel and Selective Glycine Transporter-1 (GlyT1) Inhibitors with Memory Enhancing Properties.
Autor: Santora VJ; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Almos TA; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Barido R; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Basinger J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Bellows CL; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Bookser BC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Breitenbucher JG; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Broadbent NJ; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Cabebe C; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chai CK; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chen M; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chow S; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Chung M; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Crickard L; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Danks AM; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Freestone GC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Gitnick D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Gupta V; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Hoffmaster C; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Hudson AR; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Kaplan AP; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Kennedy MR; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Lee D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Limberis J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Ly K; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Mak CC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Masatsugu B; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Morse AC; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Na J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Neul D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Nikpur J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Peters M; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Petroski RE; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Renick J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Sebring K; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Sevidal S; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Tabatabaei A; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Wen J; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Yan Y; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Yoder ZW; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States., Zook D; Dart NeuroScience LLC , 12278 Scripps Summit Drive , San Diego , California 92121 , United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2018 Jul 26; Vol. 61 (14), pp. 6018-6033. Date of Electronic Publication: 2018 Jul 11.
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6
Akademický článek
Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics.
Autor: El-Serafi, Ibrahim1,2 (AUTHOR) i.elserafi@ajman.ac.ae, Steele, Sinclair3 (AUTHOR), Mudigonda, Koteshwara (AUTHOR)
Publikováno v: Advances in Pharmacological & Pharmaceutical Sciences. 6/27/2024, Vol. 2024, p1-16. 16p.
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7
Akademický článek
Discovery of Selective Phosphodiesterase 1 Inhibitors with Memory Enhancing Properties.
Autor: Dyck B; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Branstetter B; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Gharbaoui T; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Hudson AR; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Breitenbucher JG; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Gomez L; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Botrous I; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Marrone T; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Barido R; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Allerston CK; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Cedervall EP; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Xu R; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Sridhar V; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Barker R; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Aertgeerts K; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Schmelzer K; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Neul D; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Lee D; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Massari ME; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Andersen CB; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Sebring K; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Zhou X; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Petroski R; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Limberis J; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Augustin M; Proteros Biostructures GmbH , Bunsenstraße 7a, D-82152 Martinsried, Germany., Chun LE; Berylllium , 7869 NE Day Road West, Bainbridge Island, Washington 98110, United States., Edwards TE; Berylllium , 7869 NE Day Road West, Bainbridge Island, Washington 98110, United States., Peters M; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States., Tabatabaei A; Dart Neuroscience LLC , 12278 Scripps Summit Drive, San Diego, California 92131, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2017 Apr 27; Vol. 60 (8), pp. 3472-3483. Date of Electronic Publication: 2017 Apr 13.
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8
Akademický článek
Design and Synthesis of Novel and Selective Phosphodiesterase 2 (PDE2a) Inhibitors for the Treatment of Memory Disorders.
Autor: Gomez L; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Massari ME; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Vickers T; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Freestone G; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Vernier W; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Ly K; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Xu R; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., McCarrick M; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Marrone T; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Metz M; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Yan YG; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Yoder ZW; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Lemus R; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Broadbent NJ; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Barido R; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Warren N; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Schmelzer K; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Neul D; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Lee D; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Andersen CB; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Sebring K; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Aertgeerts K; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Zhou X; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Tabatabaei A; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Peters M; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States., Breitenbucher JG; Dart Neuroscience LLC, 12278 Scripps Summit Drive, San Diego, California 92131, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2017 Mar 09; Vol. 60 (5), pp. 2037-2051. Date of Electronic Publication: 2017 Feb 21.
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9
Akademický článek
A Review of CYP-Mediated Drug Interactions: Mechanisms and In Vitro Drug-Drug Interaction Assessment.
Autor: Lee, Jonghwa1 (AUTHOR) jlbeers@uw.edu, Beers, Jessica L.1 (AUTHOR), Geffert, Raeanne M.1 (AUTHOR), Jackson, Klarissa D.1 (AUTHOR) jlee497@email.unc.edu
Publikováno v: Biomolecules (2218-273X). Jan2024, Vol. 14 Issue 1, p99. 26p.
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10
Akademický článek
In Vitro Kinetic Characterization of Axitinib Metabolism.
Autor: Zientek MA; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.) michael.zientek@pfizer.com., Goosen TC; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Tseng E; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Lin J; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Bauman JN; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Walker GS; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Kang P; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Jiang Y; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Freiwald S; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Neul D; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.)., Smith BJ; Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., San Diego, California (M.A.Z, P.K., Y.J, S.F., D.N, B.J.S.); and Pharmacokinetics, Pharmacodynamics, and Drug Metabolism, Pfizer Inc., Groton, Connecticut (T.C.G., E.T., J.L., J.N.B, G.S.W.).
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2016 Jan; Vol. 44 (1), pp. 102-14. Date of Electronic Publication: 2015 Oct 28.
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