Pleiotropic ZIP8 A391T implicates abnormal manganese homeostasis in complex human disease.

Autor: Sunuwar L; Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Frkatović A; Genos Glycoscience Research Laboratory, Zagreb, Croatia., Sharapov S; Laboratory of Glycogenomics, Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia., Wang Q; Department of Medicine, Division of Cardiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Neu HM; University of Maryland School of Pharmacy, University of Maryland, Baltimore, Maryland, USA., Wu X; Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Haritunians T; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Wan F; Department of Biochemistry and Molecular Biology and.; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA., Michel S; University of Maryland School of Pharmacy, University of Maryland, Baltimore, Maryland, USA., Wu S; Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Donowitz M; Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., McGovern D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Lauc G; Genos Glycoscience Research Laboratory, Zagreb, Croatia., Sears C; Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA., Melia J; Department of Medicine, Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Publikováno v: JCI insight [JCI Insight] 2020 Oct 15; Vol. 5 (20). Date of Electronic Publication: 2020 Oct 15.

Characterization of Acinetobacter baumannii Copper Resistance Reveals a Role in Virulence.

Autor: Williams CL; Department of Microbiology & Immunology, Uniformed Services University, Bethesda, MD, United States., Neu HM; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, MD, United States., Alamneh YA; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Reddinger RM; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Jacobs AC; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Singh S; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Abu-Taleb R; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Michel SLJ; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Baltimore, MD, United States., Zurawski DV; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, United States., Merrell DS; Department of Microbiology & Immunology, Uniformed Services University, Bethesda, MD, United States.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2020 Feb 06; Vol. 11, pp. 16. Date of Electronic Publication: 2020 Feb 06 (Print Publication: 2020).

Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly.

Autor: Xu X; City University of New York Advanced Science Research Center, City University of New York, New York, NY 10017.; PhD Program in Biochemistry, The Graduate Center, City University of New York, New York, NY 10017., Godoy-Ruiz R; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Adipietro KA; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Peralta C; City University of New York Advanced Science Research Center, City University of New York, New York, NY 10017., Ben-Hail D; City University of New York Advanced Science Research Center, City University of New York, New York, NY 10017., Varney KM; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Cook ME; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Roth BM; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Wilder PT; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Cleveland T; National Institute of Standards, Rockville, MD 20899., Grishaev A; National Institute of Standards, Rockville, MD 20899., Neu HM; University of Maryland School of Pharmacy, University of Maryland, Baltimore, MD 21201., Michel SLJ; University of Maryland School of Pharmacy, University of Maryland, Baltimore, MD 21201., Yu W; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; University of Maryland School of Pharmacy, University of Maryland, Baltimore, MD 21201., Beckett D; Department of Chemistry & Biochemistry, University of Maryland, College Park, MD 20742., Rustandi RR; Merck & Co., Inc., Kenilworth, NJ 07033., Lancaster C; Merck & Co., Inc., Kenilworth, NJ 07033., Loughney JW; Merck & Co., Inc., Kenilworth, NJ 07033., Kristopeit A; Merck & Co., Inc., Kenilworth, NJ 07033., Christanti S; Merck & Co., Inc., Kenilworth, NJ 07033., Olson JW; Merck & Co., Inc., Kenilworth, NJ 07033., MacKerell AD; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.; University of Maryland School of Pharmacy, University of Maryland, Baltimore, MD 21201., Georges AD; City University of New York Advanced Science Research Center, City University of New York, New York, NY 10017; adesgeorges@gc.cuny.edu EPozharskiy@som.umaryland.edu dweber@som.umaryland.edu.; PhD Program in Biochemistry, The Graduate Center, City University of New York, New York, NY 10017.; PhD Program in Chemistry, The Graduate Center, City University of New York, New York, NY 10017.; Department of Chemistry & Biochemistry, City College of New York, New York, NY 10031., Pozharski E; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201; adesgeorges@gc.cuny.edu EPozharskiy@som.umaryland.edu dweber@som.umaryland.edu.; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201., Weber DJ; Department of Biochemistry & Molecular Biology, University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201; adesgeorges@gc.cuny.edu EPozharskiy@som.umaryland.edu dweber@som.umaryland.edu.; Institute for Bioscience and Biotechnology Research, University of Maryland, Rockville, MD 20850.; The Center for Biomolecular Therapeutics, The University of Maryland School of Medicine, University of Maryland, Baltimore, MD 21201.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 14; Vol. 117 (2), pp. 1049-1058. Date of Electronic Publication: 2020 Jan 02.

Measuring Intracellular Metal Concentration via ICP-MS Following Copper Exposure.

Autor: Williams CL; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Neu HM; Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, USA., Michel SLJ; Department of Pharmaceutical Sciences, University of Maryland, Baltimore, MD, USA., Merrell DS; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. douglas.merrell@usuhs.edu.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2019; Vol. 1946, pp. 195-205.

Copper Resistance of the Emerging Pathogen Acinetobacter baumannii.

Autor: Williams CL; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Neu HM; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA., Gilbreath JJ; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA., Michel SL; Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland, USA., Zurawski DV; Wound Infections Department, Bacterial Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA., Merrell DS; Department of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA douglas.merrell@usuhs.edu.

Publikováno v: Applied and environmental microbiology [Appl Environ Microbiol] 2016 Sep 30; Vol. 82 (20), pp. 6174-6188. Date of Electronic Publication: 2016 Sep 30 (Print Publication: 2016).