Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Netty Santoso"'
Autor:
Tai-Wei Li, Adam D. Kenney, Jun-Gyu Park, Guillaume N. Fiches, Helu Liu, Dawei Zhou, Ayan Biswas, Weiqiang Zhao, Jianwen Que, Netty Santoso, Luis Martinez-Sobrido, Jacob S. Yount, Jian Zhu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results reveal that the SA
Externí odkaz:
https://doaj.org/article/92359d42839349c18b69b00619ad6b06
Autor:
Weili Kong, Tsuyoshi Hayashi, Guillaume Fiches, Qikai Xu, Mamie Z. Li, Jianwen Que, Shuai Liu, Wei Zhang, Jun Qi, Netty Santoso, Stephen J. Elledge, Jian Zhu
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 3, Pp 319-331 (2019)
Proteins usually associate with other molecules physically to execute their functions. Identifying these interactions is important for the functional analysis of proteins. Previously, we reported the parallel analysis of translated ORFs (PLATO) to co
Externí odkaz:
https://doaj.org/article/47634a56d86f47a99c7e7fa6950c3c5a
Autor:
Guillaume N Fiches, Dawei Zhou, Weili Kong, Ayan Biswas, Elshafa H Ahmed, Robert A Baiocchi, Jian Zhu, Netty Santoso
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008778 (2020)
EBV-associated gastric cancer (EBVaGC) is characterized by high frequency of DNA methylation. In this study, we investigated how epigenetic alteration of host genome contributes to pathogenesis of EBVaGC through the analysis of transcriptomic and epi
Externí odkaz:
https://doaj.org/article/993b404646e449dda04d3ca0423c8dbe
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008430 (2020)
Recent efforts have been paid to identify previously unrecognized HIV-1 latency-promoting genes (LPGs) that can potentially be targeted for eradication of HIV-1 latent reservoirs. From our earlier orthologous RNAi screens of host factors regulating H
Externí odkaz:
https://doaj.org/article/a4d11282eb6e4fd99e09066f8d667b43
Publikováno v:
PLoS Pathogens, Vol 14, Iss 11, p e1007465 (2018)
Influenza A viruses modulate host antiviral responses to promote viral growth and pathogenicity. Through viral PA-X and NS1 proteins, the virus is capable of suppressing host protein synthesis, termed "host shutoff." Although both proteins are known
Externí odkaz:
https://doaj.org/article/aa410cd4b5c54ba6846481096dbffe1e
Autor:
Netty Santoso, Jian Zhu, Ayan Biswas, Tai-Wei Li, Adam D. Kenney, Jacob S. Yount, Dawei Zhou, Guillaume Fiches, Helu Liu, Jianwen Que
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
SummarySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection leads to NF-κB activation and induction of pro-inflammatory cytokines, though the underlying mechanism for this activation is not fully understood. Our results reveal that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0becffcf5fc2310032c05f266c7c5ea1
https://doi.org/10.1101/2021.05.26.445787
https://doi.org/10.1101/2021.05.26.445787
Autor:
Viktoriya Anokhina, Netty Santoso, John D. McAnany, Jessica H. Ciesla, Hongyu Miao, Thomas A. Hilimire, Benjamin L. Miller
Publikováno v:
Bioorg Med Chem
Ribosomal frameshifting, a process whereby a translating ribosome is diverted from one reading frame to another on a contiguous mRNA, is an important regulatory mechanism in biology and an opportunity for therapeutic intervention in several human dis
Autor:
Dawei Zhou, Huachao Huang, Weili Kong, Tsuyoshi Hayashi, Netty Santoso, Jian Zhu, Guillaume Fiches, Maxime Jean, Jianwen Que
Publikováno v:
Nucleic Acids Research
Although combination antiretroviral therapy is potent to block active replication of HIV-1 in AIDS patients, HIV-1 persists as transcriptionally inactive proviruses in infected cells. These HIV-1 latent reservoirs remain a major obstacle for clearanc
Autor:
Mamie Z. Li, Jianwen Que, Qikai Xu, Weili Kong, Jun Qi, Shuai Liu, Stephen J. Elledge, Jian Zhu, Tsuyoshi Hayashi, Netty Santoso, Wei Zhang, Guillaume Fiches
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 17, Iss 3, Pp 319-331 (2019)
Genomics, Proteomics & Bioinformatics
Genomics, Proteomics & Bioinformatics
Proteins usually associate with other molecules physically to execute their functions. Identifying these interactions is important for the functional analysis of proteins. Previously, we reported the parallel analysis of translated ORFs (PLATO) to co
Autor:
Dawei Zhou, Maxime Jean, Netty Santoso, Jian Zhu, Huachao Huang, Katerina Gurova, Weili Kong, Guillaume Fiches, Andrei Purmal
Publikováno v:
J Med Virol
A cure for human immunodeficiency virus type-1 (HIV-1) has been hampered by the limitation of current combination antiretroviral therapy (cART) to address the latent reservoirs in HIV-1 patients. One strategy proposed to eradicate these reservoirs is