Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Nettleship JE"'
Autor:
Palazzo L, Daniels CM, Nettleship JE, Rahman N, McPherson RL, Ong SE, Kato K, Nureki O, Leung AK, Ahel I.
ADP-ribosylation is a conserved post-translational protein modification that plays a role in all major cellular processes, particularly DNA repair, transcription, translation, stress response and cell death. Hence, dysregulation of ADP-ribosylation i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::c45ec53214303d8a5c7d58e390eb9567
https://hdl.handle.net/11588/901036
https://hdl.handle.net/11588/901036
Autor:
Tiede, C, Tang, AA, Deacon, SE, Mandal, U, Nettleship, JE, Owen, RL, George, SE, Harrison, DJ, Owens, RJ, Tomlinson, DC, McPherson, MJ
We have designed a novel non-antibody scaffold protein, termed Adhiron, based on a phytocystatin consensus sequence. The Adhiron scaffold shows high thermal stability (Tm ca. 101°C), and is expressed well in Escherichia coli. We have determined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::412d8f1ab871124cce996f6ae64987bf
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Autor:
Soloviev Z; Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6AR, UK. Electronic address: z.nagurnaja.12@alumni.ucl.ac.uk., Bullock JMA; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK., James JMB; Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6AR, UK., Sauerwein AC; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK., Nettleship JE; PPUK, Research Complex at Harwell, Rutherford Appleton Laboratory, Oxford OX11 0FA, UK; Division of Structural Biology, University of Oxford, The Wellcome Centre for Human Genetics, Headington, Oxford, UK., Owens RJ; PPUK, Research Complex at Harwell, Rutherford Appleton Laboratory, Oxford OX11 0FA, UK; Division of Structural Biology, University of Oxford, The Wellcome Centre for Human Genetics, Headington, Oxford, UK., Hansen DF; Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6AR, UK., Topf M; Institute of Structural and Molecular Biology, Birkbeck College, University of London, London WC1E 7HX, UK; Centre for Structural Systems Biology, Heinrich-Pette-Institut, Leibniz-Institut für Experimentelle Virologie, Hamburg, Germany., Thalassinos K; Institute of Structural and Molecular Biology, Division of Biosciences, University College London, London WC1E 6AR, UK. Electronic address: k.thalassinos@ucl.ac.uk.
Publikováno v:
Biochimica et biophysica acta. Proteins and proteomics [Biochim Biophys Acta Proteins Proteom] 2022 Mar 01; Vol. 1870 (3), pp. 140759. Date of Electronic Publication: 2022 Jan 18.
Autor:
Lukacik P; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire, United Kingdom.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom., Owen CD; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire, United Kingdom.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom., Harris G; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom., Bolla JR; Department of Chemistry, University of Oxford, Oxford, United Kingdom., Picaud S; Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom., Alibay I; Department of Biochemistry, University of Oxford, Oxford, United Kingdom., Nettleship JE; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Bird LE; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Owens RJ; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Biggin PC; Department of Biochemistry, University of Oxford, Oxford, United Kingdom., Filippakopoulos P; Structural Genomics Consortium, University of Oxford, Oxford, United Kingdom., Robinson CV; Department of Chemistry, University of Oxford, Oxford, United Kingdom., Walsh MA; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxfordshire, United Kingdom.; Research Complex at Harwell, Harwell Science and Innovation Campus, Didcot, Oxfordshire, United Kingdom.
Publikováno v:
PloS one [PLoS One] 2021 Oct 15; Vol. 16 (10), pp. e0256070. Date of Electronic Publication: 2021 Oct 15 (Print Publication: 2021).