Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Neta Pessah"'
Autor:
Naama Hen, Richard H. Finnell, Neta Pessah, Bogdan J. Wlodarczyk, Boris Yagen, Meir Bialer, Dan Kaufmann
Publikováno v:
Epilepsia. 51:1944-1953
Summary Purpose: α-Fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide (α-F-TMCD) and α-Cl-TMCD, are α-halo derivatives of TMCD, the corresponding amide of a cyclopropane analog of valproic acid (VPA). This study aimed to comparatively evaluate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4bb4f9395538ce13db0dbc39f80a51
https://doi.org/10.1111/j.1528-1167.2010.02684.x
https://doi.org/10.1111/j.1528-1167.2010.02684.x
Publikováno v:
Angewandte Chemie. 115:4632-4637
An appropriate dendrimer could be structur-allydesignedtoreleaseallofitstailmoleculeswithasinglecleavageeventatthedendrimer'score.Hereweproposethedesign and synthesis of a novel dendritic structure with atriggerthatcaninitiatethefragmentationoftheden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af93a06873cde245039999c77e57eb4
https://doi.org/10.1002/ange.200351962
https://doi.org/10.1002/ange.200351962
Autor:
Maya Zigler, Anna Sagalov, Nufar Edinger, Alexei Shir, Neta Pessah, Yair Razvag, Shoshana Klein, Alexander Levitzki, Meital Reches, Salim Joubran
Publikováno v:
Bioconjugate Chemistry
The delivery of nucleic acids into cells is an attractive approach for cancer therapy. Polyethylenimine (PEI) is among the most efficient nonviral carriers. Recent studies have demonstrated that PEI can be conjugated to targeting ligands, such as epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9448d365f5c4515ef9af33d656b7a2a1
Autor:
Meir Bialer, Boris Yagen, Naama Hen, Jakob A. Shimshoni, Richard H. Finnell, Neta Pessah, Bogdan J. Wlodarczyk
Publikováno v:
Epilepsybehavior : EB. 22(3)
A series of glycinamide conjugates and N-methoxy amide derivatives of valproic acid (VPA) analogs and constitutional isomers were synthesized and evaluated for anticonvulsant activity. Of all compounds synthesized and tested, only N-methoxy-valnoctam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97497af3c3fdfdc08f459269c71b994
https://pubmed.ncbi.nlm.nih.gov/21959082
https://pubmed.ncbi.nlm.nih.gov/21959082
Autor:
Neta, Pessah, Dan, Kaufmann, Boris, Yagen, Naama, Hen, Bogdan, Wlodarczyk, Richard H, Finnell, Meir, Bialer
Publikováno v:
Epilepsia. 51(10)
α-Fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide (α-F-TMCD) and α-Cl-TMCD, are α-halo derivatives of TMCD, the corresponding amide of a cyclopropane analog of valproic acid (VPA). This study aimed to comparatively evaluate the pharmacodynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24744365f14ecd9c25e22313a45cd029
https://pubmed.ncbi.nlm.nih.gov/20738383
https://pubmed.ncbi.nlm.nih.gov/20738383
Publikováno v:
Journal of medicinal chemistry. 52(8)
2,2,3,3-Tetramethylcyclopropanecarboxylic acid (TMCA, 4) is a cyclic analogue of the antiepileptic drug (AED) valproic acid (VPA) (1). alpha-F, alpha-Cl, alpha-Br, and alpha-methyl derivatives of 4 and their amides were synthesized and tested in rode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff2868ed6d98ec73d73760f54695d909
https://pubmed.ncbi.nlm.nih.gov/19296679
https://pubmed.ncbi.nlm.nih.gov/19296679
Autor:
Boris Yagen, Neta Pessah, Richard H. Finnell, Bogdan J. Wlodarczyk, Meir Bialer, Jakob A. Shimshoni
Publikováno v:
Epilepsia. 49(7)
Summary Purpose: The purpose of this study was to evaluate the anticonvulsant activity and teratogenic potential of branched aliphatic acylureas represented by isovaleroylurea (IVU), pivaloylurea (PVU) and 3,3-dimethylbutanoylurea (DBU), as potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a95b492d64834ef574d64ff36e10975
https://pubmed.ncbi.nlm.nih.gov/18435754
https://pubmed.ncbi.nlm.nih.gov/18435754
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 10(11)
"Chemical adaptor systems" are molecules used to link different functionalities, based on unique reactivity that allows controlled fragmentation. Two different mechanistic reactivities were used to prepare chemical adaptor systems. The first is based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9d6584b39f5293ce6e3b0d33fa44960
https://pubmed.ncbi.nlm.nih.gov/15195294
https://pubmed.ncbi.nlm.nih.gov/15195294
Autor:
Noam Shomron, Neta Pessah, Hong Xin, Gil Ast, Katherine S. Bowdish, Doron Shabat, Mika Reznik, Ferda Yantiri, Marina Shamis
Publikováno v:
Bioorganicmedicinal chemistry. 12(8)
Two new prodrugs of CPT were synthesized, based on carbamate linkages between the 20-hydroxy group of CPT and a linker designed to be enzymatically removed by either Penicillin-G-Amidase or catalytic antibody 38C2. Cell growth inhibition assays showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a838eac20879fe84d6584f00114d1b25
https://pubmed.ncbi.nlm.nih.gov/15051055
https://pubmed.ncbi.nlm.nih.gov/15051055
Publikováno v:
Angewandte Chemie (International ed. in English). 42(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c34d9d9dd6f14248f6f7a965625a0d1
https://pubmed.ncbi.nlm.nih.gov/12548691
https://pubmed.ncbi.nlm.nih.gov/12548691