Gut microbiota-derived Metabolite, Shikimic Acid, inhibits vascular smooth muscle cell proliferation and migration.

Autor: Kumariya S; Department of Physiology and Pharmacology, Center for Hypertension and Personalized Medicine, University of Toledo, College of Medicine and Life Sciences, Toledo, OH, USA., Grano de Oro A; Department of Physiology and Pharmacology, Center for Hypertension and Personalized Medicine, University of Toledo, College of Medicine and Life Sciences, Toledo, OH, USA., Nestor-Kalinoski AL; Department of Surgery, University of Toledo, College of Medicine and Life Sciences, Toledo, OH, USA., Joe B; Department of Physiology and Pharmacology, Center for Hypertension and Personalized Medicine, University of Toledo, College of Medicine and Life Sciences, Toledo, OH, USA., Osman I; Department of Physiology and Pharmacology, Center for Hypertension and Personalized Medicine, University of Toledo, College of Medicine and Life Sciences, Toledo, OH, USA. Electronic address: islam.osman@utoledo.edu.

Publikováno v: Biochemical pharmacology [Biochem Pharmacol] 2024 Nov; Vol. 229, pp. 116524. Date of Electronic Publication: 2024 Sep 07.

Novel 3D Flipwell system that models gut mucosal microenvironment for studying interactions between gut microbiota, epithelia and immunity.

Autor: Beamer MA; Department of Cell & Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH, 43614, USA.; Division of Pediatric Rheumatology, Department of Pediatrics, University of Michigan, Ann Arbor, MI, 48109, USA., Zamora C; College of Natural Sciences and Mathematics Instrumentation Center, University of Toledo, 3100 West Towerview Blvd, Bowman-Oddy 1073, Toledo, OH, 43606, USA., Nestor-Kalinoski AL; Department of Surgery, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH, 43614, USA., Fernando V; Department of Cell & Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH, 43614, USA., Sharma V; Department of Cell & Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH, 43614, USA., Furuta S; Department of Cell & Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH, 43614, USA. sxf494@case.edu.; MetroHealth Medical Center, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, 2500 MetroHealth Drive, Cleveland, OH, 44109, USA. sxf494@case.edu.

Publikováno v: Scientific reports [Sci Rep] 2023 Jan 17; Vol. 13 (1), pp. 870. Date of Electronic Publication: 2023 Jan 17.

Positional Context of Myonuclear Transcription During Injury-Induced Muscle Regeneration.

Autor: Buckley KH; School of Exercise and Rehabilitation Sciences, University of Toledo, Toledo, OH, United States., Nestor-Kalinoski AL; Advanced Microscopy and Imaging Center, University of Toledo, Toledo, OH, United States., Pizza FX; School of Exercise and Rehabilitation Sciences, University of Toledo, Toledo, OH, United States.

Publikováno v: Frontiers in physiology [Front Physiol] 2022 Mar 23; Vol. 13, pp. 845504. Date of Electronic Publication: 2022 Mar 23 (Print Publication: 2022).

Loss of Nitric Oxide Induces Fibrogenic Response in Organotypic 3D Co-Culture of Mammary Epithelia and Fibroblasts-An Indicator for Breast Carcinogenesis.

Autor: Ren G; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH 43614, USA., Zheng X; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH 43614, USA., Sharma V; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH 43614, USA., Letson J; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH 43614, USA., Nestor-Kalinoski AL; Department of Surgery, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH 43614, USA., Furuta S; Department of Cancer Biology, College of Medicine and Life Sciences, University of Toledo Health Science Campus, 3000 Arlington Ave., Toledo, OH 43614, USA.

Publikováno v: Cancers [Cancers (Basel)] 2021 Jun 05; Vol. 13 (11). Date of Electronic Publication: 2021 Jun 05.

Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator-activated receptor α.

Autor: Gordon DM; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA.; Center for Diabetes and Endocrine Research (CeDER), University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Neifer KL; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Hamoud AA; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Hawk CF; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Nestor-Kalinoski AL; Advanced Microscopy and Imaging Center, Department of Surgery, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Miruzzi SA; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Morran MP; Advanced Microscopy and Imaging Center, Department of Surgery, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA., Adeosun SO; Department of Physiology and Biophysics, Cardiorenal and Metabolic Diseases Research Center, University of Mississippi Medical Center, Jackson, Mississippi, USA., Sarver JG; Center for Drug Design and Development (CD3), Department of Pharmacology and Experimental Therapeutics, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, Ohio, USA., Erhardt PW; Center for Drug Design and Development (CD3), Department of Medicinal and Biological Chemistry, University of Toledo College of Pharmacy and Pharmaceutical Sciences, Toledo, Ohio, USA., McCullumsmith RE; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA.; ProMedica, Toledo, Ohio, USA., Stec DE; Department of Physiology and Biophysics, Cardiorenal and Metabolic Diseases Research Center, University of Mississippi Medical Center, Jackson, Mississippi, USA., Hinds TD Jr; Department of Neurosciences, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA Terry.Hinds@utoledo.edu.; Center for Diabetes and Endocrine Research (CeDER), University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, USA.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2020 Jul 17; Vol. 295 (29), pp. 9804-9822. Date of Electronic Publication: 2020 May 13.