Translating single-neuron axonal reconstructions into meso-scale connectivity statistics in the mouse somatosensory thalamus

Autor: Nestor Timonidis, Rembrandt Bakker, Mario Rubio-Teves, Carmen Alonso-Martínez, Maria Garcia-Amado, Francisco Clascá, Paul H. E. Tiesinga

Publikováno v: Frontiers in Neuroinformatics, Vol 17 (2023)

Characterizing the connectomic and morphological diversity of thalamic neurons is key for better understanding how the thalamus relays sensory inputs to the cortex. The recent public release of complete single-neuron morphological reconstructions ena

Externí odkaz: https://doaj.org/article/3d49a4ae94d14baca474d3064f924d41

Progress towards a cellularly resolved mouse mesoconnectome is empowered by data fusion and new neuroanatomy techniques

Autor: Paul H. E. Tiesinga, Nestor Timonidis

Publikováno v: Neuroscience and Biobehavioral Reviews, 128, pp. 569-591
Neuroscience & Biobehavioral Reviews, Vol. 128
Neuroscience and Biobehavioral Reviews, 128, 569-591

Over the past decade there has been a rapid improvement in techniques for obtaining large-scale cellular level data related to the mouse brain connectome. However, a detailed mapping of cell-type-specific projection patterns is lacking, which would,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c748bd2ea009cca0ce4b3c4fc65c5f8f

Prediction of a Cell-Class-Specific Mouse Mesoconnectome Using Gene Expression Data

Autor: Paul H. E. Tiesinga, Nestor Timonidis, Rembrandt Bakker

Publikováno v: Neuroinformatics, 18, pp. 611-626
Neuroinformatics, 18, 611-626
Neuroinformatics, Vol. 18, No. 4
Neuroinformatics

Reconstructing brain connectivity at sufficient resolution for computational models designed to study the biophysical mechanisms underlying cognitive processes is extremely challenging. For such a purpose, a mesoconnectome that includes laminar and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f89edcf1c593acf6956d7b828c4b879