Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Nestor Rosales"'
Expression of the Carboxy-Terminal Portion of MUC16/CA125 Induces Transformation and Tumor Invasion.
Autor:
Thapi D Rao, Huasong Tian, Xun Ma, Xiujun Yan, Sahityasri Thapi, Nikolaus Schultz, Nestor Rosales, Sebastien Monette, Amy Wang, David M Hyman, Douglas A Levine, David Solit, David R Spriggs
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126633 (2015)
The CA125 antigen is found in the serum of many patients with serous ovarian cancer and has been widely used as a disease marker. CA125 has been shown to be an independent factor for clinical outcome in this disease. In The Cancer Genome Atlas ovaria
Externí odkaz:
https://doaj.org/article/6627675a7f23444b9ca77c59e7a3631d
Supplementary Figure 1 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 1 depicts copy number alterations in the described cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8092c0a779e8af5f72ce9dfe30cdf632
https://doi.org/10.1158/1541-7786.22525995.v1
https://doi.org/10.1158/1541-7786.22525995.v1
Most of the currently used cancer chemotherapies are based on compounds that inhibit general cellular mechanisms, such as DNA replication or tubulin function, and lack specificity in relation to features of the cancer cell. Recent advances in genomic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86dcb0823353fa44faef233db2ee87b5
https://doi.org/10.1158/1535-7163.c.6535449
https://doi.org/10.1158/1535-7163.c.6535449
Autor:
Oladapo O. Yeku, David R. Spriggs, Hakim Djaballah, Ouathek Ouerfelli, Alexia Iasonos, Qin Zhou, Irva E. Veillard, Raj Kumar, Nestor Rosales, Robin Manson, Guangli Yang, Stephanie Eng, Mengyao Xu, Thapi D. Rao
Significant strides have been made in the development of precision therapeutics for cancer. Aberrantly expressed glycoproteins represent a potential avenue for therapeutic development. The MUC16/CA125 glycoprotein serves as a biomarker of disease and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d365d2b6f36ad9a7bab12b06f6b843
https://doi.org/10.1158/1535-7163.c.6543348
https://doi.org/10.1158/1535-7163.c.6543348
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Table 1 shows point mutations found in DSRCT samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18101e727b13883957a6aa77461d9c6b
https://doi.org/10.1158/1541-7786.22525983
https://doi.org/10.1158/1541-7786.22525983
Supplementary Figure 3 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 3 provides a breakdown of the structural variant types found via whole genome sequencing in DSRCT samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418c34cb259455575b8d45bb37c7fa9d
https://doi.org/10.1158/1541-7786.22525989
https://doi.org/10.1158/1541-7786.22525989
Supplementary Figure 2 from Comprehensive Molecular Profiling of Desmoplastic Small Round Cell Tumor
Autor:
Neerav Shukla, Marc Ladanyi, Ahmet Zehir, Elli Papaemmanuil, Andrew L. Kung, Paul A. Meyers, Leonard H. Wexler, Michael P. LaQuaglia, Todd E. Heaton, Justin T. Gerstle, Gunes Gundem, Daoqi You, Nancy Bouvier, Katherine A. Thornton, Mrinal M. Gounder, William D. Tap, Shakeel Modak, Nestor Rosales, Glorymar I. Sanchez, Diego F. Coutinho, Filemon Dela Cruz, Max F. Levine, Anita S. Bowman, Emily K. Slotkin
Supplementary Figure 2 depicts whole genome sequencing findings
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1235fa2aa5fe711e16466965bf6c8325
https://doi.org/10.1158/1541-7786.22525992.v1
https://doi.org/10.1158/1541-7786.22525992.v1