Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nessa Hawkins"'
Autor:
Nessa Hawkins, Mei-Mei Tsai, Charles Henley, Ching Chen, William G. Richards, Xuechen Xia, Edward Shatzen, Michael Eschenberg, Vivian Bi, Wei Wang, Jennitte Stevens, S. C. Ward, Russell C. Cattley, Xiaodong Li, Thomas J. Wronski, James W. Davis, Victoria Shalhoub, Lisa Renshaw
Publikováno v:
Journal of Clinical Investigation. 122:2543-2553
Chronic kidney disease-mineral and bone disorder (CKD-MBD) is associated with secondary hyperparathyroidism (HPT) and serum elevations in the phosphaturic hormone FGF23, which may be maladaptive and lead to increased morbidity and mortality. To deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc48acdb0029f63226cb4b898ef9be9
https://doi.org/10.1172/jci61405
https://doi.org/10.1172/jci61405
Autor:
Yang Li, Minghan Wang, Helene Baribault, Jackie Sheng, Nessa Hawkins, Jamila Gupte, Jonitha Gardner, Xinle Wu, Steven Vonderfecht, Jennifer Weiszmann, Jennitte Stevens, Hongfei Ge
Publikováno v:
Journal of Molecular Biology. 418:82-89
Three fibroblast growth factor (FGF) molecules, FGF19, FGF21, and FGF23, form a unique subfamily that functions as endocrine hormones. FGF19 and FGF21 can regulate glucose, lipid, and energy metabolism, while FGF23 regulates phosphate homeostasis. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc75b7cd637f518e8c0e28287159148
https://doi.org/10.1016/j.jmb.2012.02.027
https://doi.org/10.1016/j.jmb.2012.02.027
Autor:
Jennifer Weiszmann, Bryan Lemon, Xiaofan Li, Nessa Hawkins, Jamila Gupte, Jie Tang, Xinle Wu, Yang Li, Hongfei Ge, Richard A. Lindberg
Publikováno v:
Proceedings of the National Academy of Sciences. 106:14379-14384
FGF19 is a hormone that regulates bile acid and glucose homeostasis. Progress has been made in identifying cofactors for receptor activation. However, several functions of FGF19 have not yet been fully defined, including the actions of FGF19 on targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f737fb1ba6a098d4215362a7448a4a
https://doi.org/10.1073/pnas.0907812106
https://doi.org/10.1073/pnas.0907812106
Autor:
S. Scully, Paul J. Kostenuik, James McCabe, Xiaodong Li, Denise Dwyer, Robin Elliott, William C. Dougall, Hung Q. Nguyen, Michael S. Ominsky, Luke Li, John K. Sullivan, William J. Boyle, William S. Simonet, Marina Stolina, Sean Morony, Gwyneth Van, Frank Asuncion, Russ Cattley, Mario Grisanti, Hong Lin Tan, Carol Kurahara, Kelly S Warmington, Ching Chen, Nessa Hawkins, Ning Sun
Publikováno v:
Journal of Bone and Mineral Research. 24:182-195
RANKL is a TNF family member that mediates osteoclast formation, activation, and survival by activating RANK. The proresorptive effects of RANKL are prevented by binding to its soluble inhibitor osteoprotegerin (OPG). Recombinant human OPG-Fc recogni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe68a4e1ff762f5c5e05b59a158cd1d3
https://doi.org/10.1359/jbmr.081112
https://doi.org/10.1359/jbmr.081112
Autor:
Linda O. Narhi, Grant Shimamoto, John S. Philo, Nessa Hawkins, Tsutomu Arakawa, Jie Wen, Robert Rosenfeld, Richard Lee, Tiansheng Li
Publikováno v:
The Journal of Peptide Research. 50:300-309
The solution structure and stability of rat and human ciliary neurotrophic factor (CNTF) were examined by circular dichroism (CD), Fourier transform infrared (FTIR) and fluorescence spectroscopy and sedimentation equilibrium analyses. The secondary s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ae91483fd129a68e56255f6e820049
https://doi.org/10.1111/j.1399-3011.1997.tb01471.x
https://doi.org/10.1111/j.1399-3011.1997.tb01471.x
Autor:
Xiaofan Li, Jennitte Stevens, Hui Tian, Jennifer Weiszmann, Richard A. Lindberg, Jin-Long Chen, Xinle Wu, Yang Li, Wenyan Shen, Bryan Lemon, Nessa Hawkins, Jamila Gupte
Publikováno v:
Journal of Biological Chemistry. 283:33304-33309
FGF19 subfamily proteins (FGF19, FGF21, and FGF23) are unique members of fibroblast growth factors (FGFs) that regulate energy, bile acid, glucose, lipid, phosphate, and vitamin D homeostasis in an endocrine fashion. Their activities require the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc6f9661811ee48e286168493ced2688
https://doi.org/10.1074/jbc.m803319200
https://doi.org/10.1074/jbc.m803319200
Autor:
S. Scully, Steve Kaufman, Grant Shimamoto, E. Davy, Colin R. Dunstan, Mario Grisanti, Nessa Hawkins, L. Chiu, Gwyneth Van, William J. Boyle, Gary Elliott, J. Beck, Victoria Shalhoub, David L. Lacey, Michael J. Kelley, R. Manoukian, Meiying Qi
Publikováno v:
British Journal of Haematology. 111:501-512
Osteoclast precursors (OCPs) circulate in the mononuclear fraction of peripheral blood (PB), but their abundance and surface characteristics are unknown. Previous studies suggest that the receptor activator for NF-kappaB (RANK) on cytokine-treated OC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ed69115df64ecc646ee57cfe83b08f0
https://doi.org/10.1046/j.1365-2141.2000.02379.x
https://doi.org/10.1046/j.1365-2141.2000.02379.x
Autor:
Victoria Shalhoub, J. Beck, Colin R. Dunstan, S. Scully, Grant Shimamoto, William J. Boyle, E. Davy, R. Manoukian, L. Chiu, Gwyneth Van, Mario Grisanti, Nessa Hawkins, Steve Kaufman, David L. Lacey, Michael J. Kelley, Meiying Qi, Gary Elliott
Publikováno v:
British Journal of Haematology. 111:501-512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d90bb4aec435808137b35a43606621
https://doi.org/10.1111/j.1365-2141.2000.02379.x
https://doi.org/10.1111/j.1365-2141.2000.02379.x
Autor:
John M. Delaney, Xing-Zhong Xia, Nessa Hawkins, Meena Ramakrishnan, Gang Yu, Masayo Kornuc, Susan McCabe, Tom Boone, Lars Eyde Theill, Wan-rong Qiu, Giorgio Senaldi, Ildiko Sarosi, Jane Guo, Marina Stolina, Hailing Hsu, Michael J. Kelley, William J. Boyle
Publikováno v:
Nature Immunology. 1:252-256
We report that the tumor neurosis factor homolog APRIL (a proliferation-inducing ligand) stimulates in vitro proliferation of primary B and T cells and increases spleen weight due to accumulation of B cells in vivo. APRIL functions via binding to BCM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a63127a99d03ff6ce1caf68871d06630
https://doi.org/10.1038/79802
https://doi.org/10.1038/79802
Autor:
Kent Miner, Irina Solovyev, Gwyneth Van, Ling Wang, Xing-Zhong Xia, Nessa Hawkins, Hailing Hsu, David L. Lacey, Ildiko Sarosi, David K. Chang, John K. Delaney, Larry Ross, Michael J. Kelley, Sanjay D. Khare, William J. Boyle, Susan McCabe
Publikováno v:
Proceedings of the National Academy of Sciences. 97:3370-3375
TALL-1/Blys/BAFF is a member of the tumor necrosis factor (TNF) ligand superfamily that is functionally involved in B cell proliferation. Here, we describe B cell hyperplasia and autoimmune lupus-like changes in transgenic mice expressing TALL-1 unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34d6c422b76f4dade41d3a4496acc0c
https://doi.org/10.1073/pnas.97.7.3370
https://doi.org/10.1073/pnas.97.7.3370