Amelioration of Diabetic Nephropathy by Targeting Autophagy via Rapamycin or Fasting: Relation to Cell Apoptosis/Survival

Autor: Nesreen Moustafa Omar, Sherihan G. AbdelHamid, Ahmed M. Mansour, Hala O. El-Mesallamy, Khaled Gouda

Publikováno v: Current Issues in Molecular Biology, Vol 43, Iss 120, Pp 1698-1714 (2021)
Current Issues in Molecular Biology
Volume 43
Issue 3
Pages 120-1714

Autophagy has been demonstrated to have a beneficial effect on diabetic nephropathy (DN). Rapamycin, an inhibitor of mTOR, was shown to stimulate β-cell autophagy. However, its effects on preventing or ameliorating DN is unclear, and its effects are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38ed675fbc9e397770e2a7abae92796a
https://pubmed.ncbi.nlm.nih.gov/34698133

N-Acetylcysteine Mitigates Histopathological and Ultrastructural Alterations Induced by Chronic Usage of Acetaminophen in the Rat Renal Cortex

Autor: Nesreen Moustafa Omar, Samar A. Asker, Amany AbdEl Fattah Abd El Fattah, Awny Hasan Yaseen

Publikováno v: Egyptian Journal of Histology. 42:162-177

Background: Acetaminophen or N-acetyl-p-aminophenol (APAP) is a potent analgesic and antipyretic drug that is widely used. N-Acetylcysteine (NAC) is a synthetic antioxidant, acting as a free radical scavenger.Aim of the work: This work was designed t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d18f1330d97fd1c4e51985c61d02df89
https://doi.org/10.21608/ejh.2018.5336.1028

An immunohistochemical and ultrastructural analysis of the retina in tadalafil (Cialis) treated rats

Autor: Nahla Reda Sarhan, Nesreen Moustafa Omar

Publikováno v: Acta Histochemica. 120:312-322

Tadalafil (Cialis) is one of the most commonly used phosphodiesterase type5 (PDE5) inhibitors. This work aimed to analyze the histological and ultrastructural changes provoked by chronic tadalafil administration in the rat retina, correlate between s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727ef3e43d88987a1d5e7ba776f2118b
https://doi.org/10.1016/j.acthis.2018.03.002

The influence of ginger administration on cisplatin-induced cardiotoxicity in rat: Light and electron microscopic study

Autor: Amany A. El-Hawwary, Nesreen Moustafa Omar

Publikováno v: Acta histochemica. 121(5)

Cisplatin is a powerful chemotherapeutic agent. Cardiotoxicity is one of its major adverse effects. Ginger is a commonly used element in herbal medicine due to its anti-oxidant potentials. This study was planned to assess the histological changes ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6679be24d1e1fc3e9438a1e12800b35a
https://pubmed.ncbi.nlm.nih.gov/31068261

Nigella sativa oil alleviates ultrastructural alterations induced by tramadol in rat motor cerebral cortex

Autor: Nesreen Moustafa Omar

Publikováno v: Journal of Microscopy and Ultrastructure

Tramadol is an opioid analgesic used to alleviate acute and chronic pain. Nigella sativa oil is one of the traditional remedies with antioxidant activity. This study was designed in order to investigate the ultrastructural alterations induced by tram

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2697527880983a8a1ddab9e064c5196