Zobrazeno 1 - 10
of 486
pro vyhledávání: '"Nesprin"'
Autor:
Riccardo Sirtori, Michelle J. Gregoire, Emily M. Potts, Alicia Collins, Liviana Donatelli, Claudia Fallini
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that primarily affects motor neurons, leading to progressive muscle weakness and loss of voluntary muscle control. While the exact cause of ALS is not fully understood, emer
Externí odkaz:
https://doaj.org/article/8b88ef704fdc41188bda66bde4715d39
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract This review presents a comprehensive exploration of the pivotal role played by the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex, with a particular focus on Nesprin proteins, in cellular mechanics and the pathogenesis of muscular
Externí odkaz:
https://doaj.org/article/ab69fc3ba7584311a9a0556a20f6eac9
Autor:
Theresa Paulus, Natalie Young, Emily Jessop, Carolin Berwanger, Christoph Stephan Clemen, Rolf Schröder, Rafal Ploski, Christian Hagel, Yorck Hellenbroich, Andreas Moser, Iakowos Karakesisoglou
Publikováno v:
Muscles, Vol 3, Iss 1, Pp 100-109 (2024)
SYNE2 mutations have been associated with skeletal and cardiac muscle diseases, including Emery-Dreifuss muscular dystrophy (EDMD). Here, we present a 70-year-old male patient with muscle pain and elevated serum creatine kinase levels in whom whole-e
Externí odkaz:
https://doaj.org/article/e71a6d2e4cbc420a8756d1031e1da6dd
Akademický článek
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Autor:
Shahar Taiber, Oren Gozlan, Roie Cohen, Leonardo R. Andrade, Ellen F. Gregory, Daniel A. Starr, Yehu Moran, Rebecca Hipp, Matthew W. Kelley, Uri Manor, David Sprinzak, Karen B. Avraham
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Nuclear positioning is important for the functionality of many cell types and is mediated by interactions of cytoskeletal elements and nucleoskeleton proteins. Nesprin proteins, part of the linker of nucleoskeleton and cytoskeleton (LINC) complex, ha
Externí odkaz:
https://doaj.org/article/c4bbcbe3a3a34baaae5077c63b081c52
Autor:
Tasneem Bouzid, Eunju Kim, Brandon D. Riehl, Amir Monemian Esfahani, Jordan Rosenbohm, Ruiguo Yang, Bin Duan, Jung Yul Lim
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-12 (2019)
Abstract Mesenchymal stem cells (MSCs) show tremendous promise as a cell source for tissue engineering and regenerative medicine, and are understood to be mechanosensitive to external mechanical environments. In recent years, increasing evidence poin
Externí odkaz:
https://doaj.org/article/900c5b04d20c4afaa8dac45b51e1ea8b
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Syne2b/nesprin-2 is a giant protein implicated in tethering the nucleus to the cytoskeleton and plays an important role in maintaining cellular architecture. Epiboly is a conserved morphogenetic movement that involves extensive spreading and thinning
Externí odkaz:
https://doaj.org/article/379aababe9dc4432bdff8f1ad29e369a
Autor:
Patricia Ulm, Verena Jantsch
Publikováno v:
eLife, Vol 10 (2021)
Experiments in C. elegans reveal new insights into how the ANC-1 protein helps to anchor the nucleus and other organelles in place.
Externí odkaz:
https://doaj.org/article/295e3c51fc2746629df33f020fa4a7e2
Autor:
Hongyan Hao, Shilpi Kalra, Laura E Jameson, Leslie A Guerrero, Natalie E Cain, Jessica Bolivar, Daniel A Starr
Publikováno v:
eLife, Vol 10 (2021)
KASH proteins in the outer nuclear membrane comprise the cytoplasmic half of linker of nucleoskeleton and cytoskeleton (LINC) complexes that connect nuclei to the cytoskeleton. Caenorhabditis elegans ANC-1, an ortholog of Nesprin-1/2, contains actin-
Externí odkaz:
https://doaj.org/article/8e31d2d8cabe45c2a28ac915e4c1a995
Akademický článek
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