Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Neslihan Pinar OZATES"'
Autor:
Cigir Biray Avci, Tuba Gokdogan Edgunlu, Tugba Suzek, Neslihan Pinar Ozates, Bakiye Goker Bagca, Aysegul Demirtas Bilgic, Cilem Ozdemir, Bakiye Ugur
Publikováno v:
European Journal of Medicinal Chemistry Reports, Vol 12, Iss , Pp 100186- (2024)
Long non-coding RNAs (lncRNAs) play a dynamic role in gene expression regulation and serve as potential therapeutic targets in breast cancer. The anticancer effect of propofol, an anesthetic agent, has been proven, but its interaction with lncRNAs ha
Externí odkaz:
https://doaj.org/article/fc3949b4c3f04d98a3418ebf0c210ae8
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 13, Iss 3, Pp 611-620 (2023)
Purpose: The phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin (PI3K/AKT/ mTOR) pathway is a complex intracellular metabolic pathway that leads to cell growth and tumor proliferation and plays a key role in drug resistance in breast can
Externí odkaz:
https://doaj.org/article/df79b0320d7445379b5bdeb36f9d6307
Autor:
Burcin Tezcanli Kaymaz, Nur Selvi Gunel, Fatma Sogutlu, Neslihan Pinar Ozates Ay, Yusuf Baran, Cumhur Gunduz, Cigir Biray Avci
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 25, Iss 7, Pp 904-912 (2022)
Objective(s): STATs are one of the initial targets of emerging anti-cancer agents due to their regulatory roles in survival, apoptosis, drug response, and cellular metabolism in CML. Aberrant STAT3 activity promotes malignancy, and acts as a metaboli
Externí odkaz:
https://doaj.org/article/ad167cc2cfda4ac980a8a157e2f2d7d8
Autor:
Cigir BIRAY AVCI, Tuba GOKDOGAN EDGUNLU, Tugba SUZEK, Neslihan Pinar OZATES, Bakiye GOKER BAGCA, Aysegul DEMIRTAS BILGIC, Cilem OZDEMIR, Bakiye UGUR
Propofol (2,6-diisopropyl phenol) is an anesthetic agent frequently used in clinical practice. Besides its anesthetic properties, it exhibits many non-anesthetic effects, including antitumor activity. Propofol has an important effect on the spread of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2667c02b7c6716c8bb640a7cdf924eb5
https://doi.org/10.21203/rs.3.rs-2784773/v1
https://doi.org/10.21203/rs.3.rs-2784773/v1
Autor:
Cigir Biray Avci, Sevim Karakaş Çelik, Bakiye Uğur, Bakiye Goker Bagca, Neslihan Pinar Ozates, Aydin Boluk, Tuba Gökdoğan Edgünlü
Publikováno v:
Anti-Cancer Agents in Medicinal Chemistry. 22:356-361
Aim: The study aimed to determine the cytotoxic and apoptotic effect of propofol on glioma cells. Background: Propofol [2,6-diisopropylphenol] is a commonly used intravenous anesthetic. Propofol is known to have a mechanism of action on the PI3K-AKT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f0ed78f7a5130245fe94f8dfd9281e
https://doi.org/10.2174/1871520621666210708094328
https://doi.org/10.2174/1871520621666210708094328
Publikováno v:
Medical Oncology. 40
Although temozolomide is the primary chemotherapeutic agent in glioblastoma, current studies have focused on its combinational applications to overcome resistance by targeting multiple pathways. JAK/STAT and WNT are among the essential cancer-related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd64c0e46f52f1498cd19f1d5d99dcea
https://doi.org/10.1007/s12032-022-01897-4
https://doi.org/10.1007/s12032-022-01897-4
Autor:
Cigir Biray Avci, Cansu Caliskan Kurt, Nur Selvi Günel, Bakiye Goker Bagca, Neslihan Pinar Ozates, Fatma Sogutlu, Behrouz Shademan, Nihal Birden
Publikováno v:
Molecular Biology Reports. 48:6085-6091
Background Thyroid cancer is the most common malignant tumor of the endocrine system seen in the thyroid gland. More than 90% of thyroid cancers comprise papillary thyroid cancer (PTC) and follicular thyroid cancer (FTC). Although anaplastic thyroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d5754121b04f7d8e090882f6e72a35
https://doi.org/10.1007/s11033-021-06616-2
https://doi.org/10.1007/s11033-021-06616-2
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nur Selvi Gunel, Nuri Yildirim, Neslihan Pinar Ozates, Latife Merve Okyay, Bakiye Goker Bagca, Fatma Sogutlu, Aydin Ozsaran, Cigir Biray Avci
After revealing the anti-cancer properties of boron, which is included in the category of essential elements for human health by the World Health Organization, the therapeutic potential of boron compounds has been begun to be evaluated, and its molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb1b26df4e4b51dd005f778821c8cc7f
https://doi.org/10.21203/rs.3.rs-1645349/v1
https://doi.org/10.21203/rs.3.rs-1645349/v1
Autor:
Vahideh Tarhriz, Hojjatollah Nozad Charoudeh, Soheila Montazersaheb, Peter E. Nielsen, Neslihan Pinar Ozates Ay, Mohammad Saeid Hejazi, Cigir Biray Avci, Bakiye Goker Bagca
Publikováno v:
International Journal of Biological Macromolecules. 164:4583-4590
Peptide nucleic acid (PNA) is an amide based structural nucleic acid mimic with potential applications in gene therapeutic drug discovery. in the present study, we evaluated and compared the effects on gene expression, cell viability and apoptosis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c0856b05b801b996b22ba4f34ecf9c
https://doi.org/10.1016/j.ijbiomac.2020.09.081
https://doi.org/10.1016/j.ijbiomac.2020.09.081