Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nesli Ece Sen"'
Autor:
Nesli Ece Sen, Jessica Drost, Suzana Gispert, Sylvia Torres-Odio, Ewa Damrath, Michael Klinkenberg, Hamid Hamzeiy, Gülden Akdal, Halil Güllüoğlu, A. Nazlı Başak, Georg Auburger
Publikováno v:
Neurobiology of Disease, Vol 96, Iss , Pp 115-126 (2016)
Ataxin-2 (ATXN2) polyglutamine domain expansions of large size result in an autosomal dominantly inherited multi-system-atrophy of the nervous system named spinocerebellar ataxia type 2 (SCA2), while expansions of intermediate size act as polygenic r
Externí odkaz:
https://doaj.org/article/cb8f42da3ff6407ba98ba51f0467cbed
Autor:
Jana Key, Nesli Ece Sen, Aleksandar Arsović, Stella Krämer, Robert Hülse, Natasha Nadeem Khan, David Meierhofer, Suzana Gispert, Gabriele Koepf, Georg Auburger
Publikováno v:
Cells, Vol 9, Iss 10, p 2229 (2020)
Iron deprivation activates mitophagy and extends lifespan in nematodes. In patients suffering from Parkinson’s disease (PD), PINK1-PRKN mutations via deficient mitophagy trigger iron accumulation and reduce lifespan. To evaluate molecular effects o
Externí odkaz:
https://doaj.org/article/5f4713fee07c42098b765cf4789fad52
Autor:
Jessica Bux, Nesli Ece Sen, Isa-Maria Klink, Stefan Hauser, Matthis Synofzik, Ludger Schöls, Georg Auburger, Olaf Riess, Jeannette Hübener-Schmid
Publikováno v:
Molecular neurobiology 60(6), 3553-3567 (2023). doi:10.1007/s12035-023-03294-y
Spinocerebellar ataxia type 2 (SCA2) is an autosomal dominantly inherited neurodegenerative disease, which belongs to the trinucleotide repeat disease group with a CAG repeat expansion in exon 1 of the ATXN2 gene resulting in an ataxin-2 protein with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e7dfce9b54a549f09226c1b5e3b09c
Autor:
Maha R.A. Abdollah, Mir Hilal Ahmad, Berta Alcover-Sanchez, Alfonso Alfaro Rodríguez, Marwa A. Ali, Karim A. Alkadhi, Georg Auburger, Meheli Banerjee, Christoph G. Baums, Daria V. Belan, Tom Bleeser, Larisa Bobrovskaya, Hayrunnisa Bolay, Joline E. Brandenburg, Josiane Budni, Jennifer Burnsed, Antonio Cadiz, Katherine Carlin, Raul Chavez-Valdez, Win Ning Chen, Jacques-Olivier Coq, Stephen J. Crocker, Beatriz Cubelos, I.S. Darshini, Nicole de Buhr, Justine Debatisse, Isaac Deng, Jan Deprest, Sarah Devroe, Maria Laura Cecconi dos Santos, Olga Doszyn, Tomasz Dulski, Omer Faruk Eker, Irina V. Ekimova, Barbara Falquetto, Ana Fernández, Matthew J. Fogarty, Abdelrahman Y. Fouda, Luis Gandía, Antonio G. García, Angélica González Maciel, Denis Grandgirard, Bernadette E. Grayson, David A. Greenberg, Natalia Gulyaeva, Sangeetha Gupta, Bora Gürer, Omar Guzmán-Quevedo, Daniel Gyamfi, Sarah Hamimi, Junqiu He, Sung-Ha Hong, Hiroyuki Ida, Salinee Jantrapirom, Lauren L. Jantzie, Mykola Kadzhaya, Jyotshna Kanungo, Ginpreet Kaur, Gabriela Serafim Keller, Sally Kelliny, Olga N. Kokiko-Cochran, Ilia Komoltsev, P. Pramod Kumar, Diego Cabral Lacerda, Geoffrey A. Lambert, Ksenia V. Lapshina, Tally M. Largent-Milnes, Ngoc Dung Le, Stephen L. Leib, Aidan A. Levine, Lulin Li, Erika Liktor-Busa, Fang Liu, Sufang Liu, Jian Luo, Raul Manhães-de-Castro, Devin W. McBride, Eduarda Behenck Medeiros, Marita Meurer, Brandon A. Miller, Amal Chandra Mondal, Thiago S. Moreira, S. Priya Narayanan, Andy Nguyen, Andrii Panteleichuk, Nuria Paricio, Yuri F. Pastukhov, Vinood B. Patel, Eugene Pedachenko, Misha Perouansky, Taras Petriv, Luca Lo Piccolo, K.V. Harish Prashanth, Victor R. Preedy, Cristina Puig, Rajkumar Rajendram, Ramalakshmi Ramasamy, Santhamani Ramasamy, Manuel Alejandro Ramirez-Lee, Trenton J. Ray, Lisienny Campoli Tono Rempel, Miriam Renz, Steffen Rex, Rafael Reynoso Robles, Susanna Ricci, Sandra Rieger, Shenandoah Robinson, Rosa María Romero Velázquez, Robert Rümmler, Francisco José Sanz, Serhii Savosko, Nada K. Sedky, Nesli-Ece Sen, Mohd. Farooq Shaikh, Shengshuai Shan, Uma Sharma, Anna Shmeleva, Gary C. Sieck, Pascal Siegert, Allie M. Smith, Phillip P. Smith, Cristina Solana-Manrique, Emmanuelle Canet Soulas, Rhea Subba, Selvakumar Subbian, Ana C. Takakura, John C. Talpos, Kin Yip Tam, Feng Tao, Zoe Tapp, Baban S Thawkar, Mai F. Tolba, Ana Elisa Toscano, Masahiro Tsuji, Ignacio Valenzuela, Marc Van de Velde, Lennart Van der Veeken, Libor Velíšek, Jana Velíšková, Diego Bulcão Visco, Sydney M. Vita, Maren von Köckritz-Blickwede, Doga Vuralli, Jennifer L. Walters, David A. Wassarman, Océane Wateau, Masamitsu Yamaguchi, Hideki Yoshida, Xin-Fu Zhou, Justyna Zmorzynska
Publikováno v:
Handbook of Animal Models in Neurological Disorders ISBN: 9780323898331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6229622e8dddc128548ffb0f2a9f3ec5
https://doi.org/10.1016/b978-0-323-89833-1.09993-6
https://doi.org/10.1016/b978-0-323-89833-1.09993-6
Autor:
Nesli-Ece Sen, Georg Auburger
Publikováno v:
Handbook of Animal Models in Neurological Disorders ISBN: 9780323898331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcde1c2943271403428df724240c8054
https://doi.org/10.1016/b978-0-323-89833-1.00013-6
https://doi.org/10.1016/b978-0-323-89833-1.00013-6
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5124 (2020)
Depletion of yeast/fly Ataxin-2 rescues TDP-43 overexpression toxicity. In mouse models of Amyotrophic Lateral Sclerosis via TDP-43 overexpression, depletion of its ortholog ATXN2 mitigated motor neuron degeneration and extended lifespan from 25 days
Externí odkaz:
https://doaj.org/article/3af3f5ff5f6347caad89083b4266dd2f
Autor:
Jessica Bux, Nesli Ece Sen, Isa-Maria Klink, Stefan Hauser, Ludger Schöls, Georg Auburger, Olaf Horst Riess, Jeannette Hübener-Schmid
Background Spinocerebellar Ataxia Type 2 (SCA2) belongs to a group of neurodegenerative diseases, inherited as an autosomal dominant trait. SCA2 is a trinucleotide repeat disease with a CAG repeat expansion in exon 1 of the ATXN2gene resulting in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfccd7039abaaa55e72b58d18bb4c835
https://doi.org/10.21203/rs.3.rs-2144417/v1
https://doi.org/10.21203/rs.3.rs-2144417/v1
Autor:
Georg Auburger, Suzana Gispert, Sylvia Torres-Odio, Marina Jendrach, Nadine Brehm, Júlia Canet-Pons, Jana Key, Nesli-Ece Sen
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3284 (2019)
Hereditary Parkinson’s disease (PD) can be triggered by an autosomal dominant overdose of alpha-Synuclein (SNCA) as stressor or the autosomal recessive deficiency of PINK1 Serine/Threonine-phosphorylation activity as stress-response. We demonstrate
Externí odkaz:
https://doaj.org/article/9119fa4bd6994a669ee5c099133dbd57
Autor:
Keren Lasker, Edor Kabashi, Victoria Shabardina, Guozhong Huang, Roberto Docampo, Anushka Sanyal, Georg Auburger, Yanniv Dorone, Iñaki Ruiz-Trillo, Anca Marian, Steven Boeynaems, Aaron D. Gitler, Garam Kim, Nesli-Ece Sen
SUMMARYBiomolecular condensation underlies the biogenesis of an expanding array of membraneless assemblies, including stress granules (SGs) which form under a variety of cellular stresses. Advances have been made in understanding the molecular gramma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8d467916b5645584562eebca0ab2bff
https://doi.org/10.1101/2021.08.23.457426
https://doi.org/10.1101/2021.08.23.457426
Autor:
Nesli-Ece Sen, Claudia Doering, Stéphane Dieterlé, R. Koenig, Suzana Gispert-Sanchez, Júlia Canet-Pons, Frédérique René, N. Hein-Fuchs, Anja Kerksiek, Melanie Vanessa Halbach, Aleksandar Arsovic, Gina Picchiarelli, D. Luetjohann, Jana Key, L.-E. Almaguer-Mederos, Raphaelle Cassel, Luc Dupuis, Georg Auburger
Publikováno v:
Neurobiology of Disease
Neurobiology of Disease, Elsevier, 2021, 152, pp.105289. ⟨10.1016/j.nbd.2021.105289⟩
Neurobiology of Disease, Vol 152, Iss, Pp 105289-(2021)
Neurobiology of Disease, 2021, 152, pp.105289. ⟨10.1016/j.nbd.2021.105289⟩
Neurobiology of disease, 152(2021):105289
Neurobiology of Disease, Elsevier, 2021, 152, pp.105289. ⟨10.1016/j.nbd.2021.105289⟩
Neurobiology of Disease, Vol 152, Iss, Pp 105289-(2021)
Neurobiology of Disease, 2021, 152, pp.105289. ⟨10.1016/j.nbd.2021.105289⟩
Neurobiology of disease, 152(2021):105289
Large polyglutamine expansions in Ataxin-2 (ATXN2) cause multi-system nervous atrophy in Spinocerebellar Ataxia type 2 (SCA2). Intermediate size expansions carry a risk for selective motor neuron degeneration, known as Amyotrophic Lateral Sclerosis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab6de08db688b0e454f8807b9b1eac19
https://www.hal.inserm.fr/inserm-03376340/file/1-s2.0-S0969996121000383-main.pdf
https://www.hal.inserm.fr/inserm-03376340/file/1-s2.0-S0969996121000383-main.pdf